147
Nanoparticle
Size and shape of
nanoparticle
Biological synthesis
process
Resistant bacteria
Observations
Reference(s)
Silver
Triangular,
18 ± 3 nm (SEM);
16 ± 2 nm (TEM)
Synthesized from leaf
extract of Ocimum
gratissimum
Multidrug-resistant E. coli
(MC-2)
Inhibition of biofilm
formation
Das et al.
(2017a)
Damage to cell surface and
production of reactive oxygen
species
Dose-dependent antimicrobial
activity
Silver
Spherical, 13.15 nm Synthesized using bark
extract of the medicinal
plant Holarrhena
pubescens
Wall ex G. Don
(HP)
Imipenem-resistant P.
aeruginosa
Antibiofilm properties of
HP-silver nanoparticles
Ali et al. (2018)
Nanoparticle-induced cell
damage and cell death
Silver nanoparticles inhibit or
restrict colonization and halt
biofilm formation
Silver
Spherical, 41–68 nm Synthesized from the
Bacillus brevis
(NCIM
2533)
Multidrug-resistant S. typhi
and S. aureus
Potential antibacterial
property
Saravanan et al.
(2018)
Zinc oxide
phytonanocomposite
10–20 nm
Synthesized using
Strychnos nux-vomica L.
(Loganiaceae)
leaf extract
Methicillin-resistant S. aureus,
multidrug-resistant E. coli, P.
aeruginosa, A. baumannii
(isolated from diabetic foot
ulcers)
Significant antimicrobial
activity
Steffy et al.
(2018)
(continued)
6 Exploring Microbial Nanotoxicity Against Drug Resistance in Bacteria