136
Alshatwi AA, Vaiyapuri Subbarayan P, Ramesh E, AL-Hazzani AA, Alsaif MA, Alwarthan AA
(2012) Al2O3 nanoparticles induce mitochondria-mediated cell death and upregulate the
expression of signaling genes in human mesenchymal stem cells. J Biochem Mol Toxicol
26:469–476
Balasubramanyam A, Sailaja N, Mahboob M, Rahman MF, Hussain SM, Grover P (2009) In vivo
genotoxicity assessment of aluminium oxide nanomaterials in rat peripheral blood cells using
the comet assay and micronucleus test. Mutagenesis 2009(24):245–251
Berntsen P, Park CY, Rothen-Rutishauser B, Tsuda A, Sager TM, Molina RM, Donaghey TC,
Alencar AM, Kasahara DI, Ericsson T, Millet EJ, Swenson J, Tschumperlin DJ, Butler JP,
Brain JD, Fredberg JJ, Gehr P, Zhou EH (2010) Biomechanical effects of environmental and
engineered particles on human airway smooth muscle cells. J R Soc Interface 7:331–340
Boyles MS, Ranninger C, Reischl R, Rurik M, Tessadri R, Kohlbacher O, Duschl A, Huber CG
(2016) Copper oxide nanoparticle toxicity profiling using untargeted metabolomics. Part Fibre
Toxicol 13:49
Bryce SM, Bemis JC, Avlasevich SL, Dertinger SD (2007) In vitro micronucleus assay scored by
flow cytometry provides a comprehensive evaluation of cytogenetic damage and cytotoxicity.
Mutat Res 630:78–91
CCOHS (Canadian Centre for Occupational Health and Safety) (2018, October 29) Course on
nanomaterials aims to protect workers. Hamilton.http://www.ccohs.ca/newsroom/news_
releases/Nanotechnology_29October2018.html
Chang X, Zhang Y, Tang M, Wang B (2013) Health effects of exposure to nano-TiO2: a metaanalysis of experimental studies. Nanoscale Res Lett 8:51
Chawla J, Kumar A (2013) Ranking carbon-based nanomaterials using cytotoxicity to minimize
public health risks. Int J Environ Eng Manag 4:301–308
Chen L, Yokel RA, Hennig B, Toborek M (2008) Manufactured aluminum oxide nanoparticles
decrease expression of tight junction proteins in brain vasculature. J Neuroimmuno Pharmacol
3(4):286–295
Cheng J, Flahaut E, Cheng SH (2007) Effect of carbon nanotubes on developing zebrafish (Danio
rerio) embryos. Environ Toxicol Chem 26:708–716
Contado C (2015) Nanomaterials in consumer products: a challenging analytical problem. Front
Chem 3:48–124
Dhawan A, Sharma V (2010) Toxicity assessment of nanomaterials: methods and challenges. Anal
Bioanal Chem 398:589–605
Ema M, Hougaard KS, Kishimoto A, Honda K (2016) Reproductive and developmental toxicity of
carbon-based nanomaterials: a literature review. Nanotoxicology 10:391–412
Grissa I, Elghoul J, Ezzi L, Chakroun S, Kerkeni E, Hassine M, El Mir L, Mehdi M, Ben Cheikh
H, Haouas Z (2015) Anemia and genotoxicity induced by sub-chronic intragastric treatment of
rats with titanium dioxide nanoparticles. Mutat Res Genet Toxicol Environ Mutagen 794:25–31
Huang CC, Hwu JR, Su WC, Shieh DB, Tzeng Y, Yeh CS (2006) Surfactant assisted hollowing of cu nanoparticles involving halide-induced corrossion–oxidation processes. Chem Eur
J 12:3805–3810
Iavicoli I, Leso V, Fontana L, Bergamaschi A (2011) Toxicological effects of titanium dioxide
nanoparticles: a review of in vitro mammalian studies. Eur Rev Med Pharmacol Sci 15:481–508
Indira TK, Lakshmi PK (2010) Magnetic nanoparticles-a review. Int J Pharm 3:1035–1042
Jennifer M, Maciej W (2013) Nanoparticle technology as a double-edged sword: cytotoxic, genotoxic and epigenetic effects on living cells. J Biomat Nanobiotechnol 24:53–63
Jia G, Wang HF, Yan L, Wang X, Pei RJ, Yan T, Zhao YL, Guo XB (2005) Cytotoxicity of carbon
nanomaterials; single-wall nanotube, multi-wall nanotube, and fullerene. Environ Sci Technol
39(5):1378–1383
Junyi L (2015) Assessing toxicity of Carbon based nanoparticles in cells and zebrafish by using
biospectrospy, Lancaster University, An alternative format thesis submitted for the degree of
Doctor of Philosophy in the Faculty of Science and Technology Lancaster University
Kahru A, Dubourguier HC (2010) From ecotoxicology to nanoecotoxicology. Toxicology
269:105–119
B. Karahalil
Alshatwi AA, Vaiyapuri Subbarayan P, Ramesh E, AL-Hazzani AA, Alsaif MA, Alwarthan AA
(2012) Al2O3 nanoparticles induce mitochondria-mediated cell death and upregulate the
expression of signaling genes in human mesenchymal stem cells. J Biochem Mol Toxicol
26:469–476
Balasubramanyam A, Sailaja N, Mahboob M, Rahman MF, Hussain SM, Grover P (2009) In vivo
genotoxicity assessment of aluminium oxide nanomaterials in rat peripheral blood cells using
the comet assay and micronucleus test. Mutagenesis 2009(24):245–251
Berntsen P, Park CY, Rothen-Rutishauser B, Tsuda A, Sager TM, Molina RM, Donaghey TC,
Alencar AM, Kasahara DI, Ericsson T, Millet EJ, Swenson J, Tschumperlin DJ, Butler JP,
Brain JD, Fredberg JJ, Gehr P, Zhou EH (2010) Biomechanical effects of environmental and
engineered particles on human airway smooth muscle cells. J R Soc Interface 7:331–340
Boyles MS, Ranninger C, Reischl R, Rurik M, Tessadri R, Kohlbacher O, Duschl A, Huber CG
(2016) Copper oxide nanoparticle toxicity profiling using untargeted metabolomics. Part Fibre
Toxicol 13:49
Bryce SM, Bemis JC, Avlasevich SL, Dertinger SD (2007) In vitro micronucleus assay scored by
flow cytometry provides a comprehensive evaluation of cytogenetic damage and cytotoxicity.
Mutat Res 630:78–91
CCOHS (Canadian Centre for Occupational Health and Safety) (2018, October 29) Course on
nanomaterials aims to protect workers. Hamilton.http://www.ccohs.ca/newsroom/news_
releases/Nanotechnology_29October2018.html
Chang X, Zhang Y, Tang M, Wang B (2013) Health effects of exposure to nano-TiO2: a metaanalysis of experimental studies. Nanoscale Res Lett 8:51
Chawla J, Kumar A (2013) Ranking carbon-based nanomaterials using cytotoxicity to minimize
public health risks. Int J Environ Eng Manag 4:301–308
Chen L, Yokel RA, Hennig B, Toborek M (2008) Manufactured aluminum oxide nanoparticles
decrease expression of tight junction proteins in brain vasculature. J Neuroimmuno Pharmacol
3(4):286–295
Cheng J, Flahaut E, Cheng SH (2007) Effect of carbon nanotubes on developing zebrafish (Danio
rerio) embryos. Environ Toxicol Chem 26:708–716
Contado C (2015) Nanomaterials in consumer products: a challenging analytical problem. Front
Chem 3:48–124
Dhawan A, Sharma V (2010) Toxicity assessment of nanomaterials: methods and challenges. Anal
Bioanal Chem 398:589–605
Ema M, Hougaard KS, Kishimoto A, Honda K (2016) Reproductive and developmental toxicity of
carbon-based nanomaterials: a literature review. Nanotoxicology 10:391–412
Grissa I, Elghoul J, Ezzi L, Chakroun S, Kerkeni E, Hassine M, El Mir L, Mehdi M, Ben Cheikh
H, Haouas Z (2015) Anemia and genotoxicity induced by sub-chronic intragastric treatment of
rats with titanium dioxide nanoparticles. Mutat Res Genet Toxicol Environ Mutagen 794:25–31
Huang CC, Hwu JR, Su WC, Shieh DB, Tzeng Y, Yeh CS (2006) Surfactant assisted hollowing of cu nanoparticles involving halide-induced corrossion–oxidation processes. Chem Eur
J 12:3805–3810
Iavicoli I, Leso V, Fontana L, Bergamaschi A (2011) Toxicological effects of titanium dioxide
nanoparticles: a review of in vitro mammalian studies. Eur Rev Med Pharmacol Sci 15:481–508
Indira TK, Lakshmi PK (2010) Magnetic nanoparticles-a review. Int J Pharm 3:1035–1042
Jennifer M, Maciej W (2013) Nanoparticle technology as a double-edged sword: cytotoxic, genotoxic and epigenetic effects on living cells. J Biomat Nanobiotechnol 24:53–63
Jia G, Wang HF, Yan L, Wang X, Pei RJ, Yan T, Zhao YL, Guo XB (2005) Cytotoxicity of carbon
nanomaterials; single-wall nanotube, multi-wall nanotube, and fullerene. Environ Sci Technol
39(5):1378–1383
Junyi L (2015) Assessing toxicity of Carbon based nanoparticles in cells and zebrafish by using
biospectrospy, Lancaster University, An alternative format thesis submitted for the degree of
Doctor of Philosophy in the Faculty of Science and Technology Lancaster University
Kahru A, Dubourguier HC (2010) From ecotoxicology to nanoecotoxicology. Toxicology
269:105–119
B. Karahalil