N
N
N
N
N
Ru
O
O
K
PPh 3
PPh 3
N
N
N
N
N
Ru
O
O
H
PPh 3
PPh 3
KN(SiMe 3 ) 2
18-crown-6
Benzene
84
86
CN
R
86 (5 mol%)
HBPin, 45
o C
C 6 H 6
HCl
R
NH 2
NH 2
94%
NH 2
91%
MeO
NH 2
44%
CF 3
R
N(BPin) 2
Scheme 37 Catalytic nitrile hydroboration using 86 as a catalyst
Scheme 38 Plausible mechanism for the nitrile hydroboration
118
A. Singh et al.
N
N
N
N
Ru
O
O
K
PPh 3
PPh 3
N
N
N
N
N
Ru
O
O
H
PPh 3
PPh 3
KN(SiMe 3 ) 2
18-crown-6
Benzene
84
86
CN
R
86 (5 mol%)
HBPin, 45
o C
C 6 H 6
HCl
R
NH 2
NH 2
94%
NH 2
91%
MeO
NH 2
44%
CF 3
R
N(BPin) 2
Scheme 37 Catalytic nitrile hydroboration using 86 as a catalyst
Scheme 38 Plausible mechanism for the nitrile hydroboration
118
A. Singh et al.