116
6 Risk Assessment and Management of Chemical Products
Fig. 6.4 Illustration of safety, health, and environmental exposures of humans and the modeling
approaches used for each case
Fig. 6.5 Number of people exposed compared to their knowledge about safe handling of a product
over its life cycle
drinking water, or air), and j indicates the exposure route (such as oral, inhalation, or
dermal). By taking into account the actual amount of a chemical that can be taken up
after an exposure (known as uptake efficiency, r ij ), the dose of the chemical can then
be defined as shown in Eq. 6.3. Defining the dose through the oral, inhalation, and
dermal exposure routes is illustrated in Fig. 6.6 as defined by the US EPA (1997):
PDI j =
1
m bw
i
(c ij × CR ij )
(6.2)
D j =
1
m bw
i
(c ij × CR ij × r ij )
(6.3)
6 Risk Assessment and Management of Chemical Products
Fig. 6.4 Illustration of safety, health, and environmental exposures of humans and the modeling
approaches used for each case
Fig. 6.5 Number of people exposed compared to their knowledge about safe handling of a product
over its life cycle
drinking water, or air), and j indicates the exposure route (such as oral, inhalation, or
dermal). By taking into account the actual amount of a chemical that can be taken up
after an exposure (known as uptake efficiency, r ij ), the dose of the chemical can then
be defined as shown in Eq. 6.3. Defining the dose through the oral, inhalation, and
dermal exposure routes is illustrated in Fig. 6.6 as defined by the US EPA (1997):
PDI j =
1
m bw
i
(c ij × CR ij )
(6.2)
D j =
1
m bw
i
(c ij × CR ij × r ij )
(6.3)