74
X. Feng et al.
Table 2.34 Catalytic asymmetric transfer hydrogenation of imines
Ar
Me
N
Ar
Me
HN
HB(C 6 F 5 ) 2 10 (10 mol %)
O
S t Bu
H 2 N
pyridine (10 mol %)
NH 3 ·BH 3 73 (1.0 equiv.)
76 (10 mol %)
CN
CN
3
5
Entry product
yield (%) ee (%)
1
5s’
Ph
Me
HN
CN
99
89
2
5t’
Me
HN
CN
EtO
96
95
3
5u’
Me
HN
CN
92
92
4
5v’
Me
HN
CN
O
O
90
90
5
5w’
Me
HN
CN
Br
98
94
6
5x’
Me
HN
CN
O
Me
99
86
X. Feng et al.
Table 2.34 Catalytic asymmetric transfer hydrogenation of imines
Ar
Me
N
Ar
Me
HN
HB(C 6 F 5 ) 2 10 (10 mol %)
O
S t Bu
H 2 N
pyridine (10 mol %)
NH 3 ·BH 3 73 (1.0 equiv.)
76 (10 mol %)
CN
CN
3
5
Entry product
yield (%) ee (%)
1
5s’
Ph
Me
HN
CN
99
89
2
5t’
Me
HN
CN
EtO
96
95
3
5u’
Me
HN
CN
92
92
4
5v’
Me
HN
CN
O
O
90
90
5
5w’
Me
HN
CN
Br
98
94
6
5x’
Me
HN
CN
O
Me
99
86