148
G. Compagnini et al.
Fig. 4.9 SERS spectra of hIAPP (250 nM) in presence of Ag and Au NPs PLAL after an incubation
time of 4 h
Figure 4.9 reports the same experiment conducted using silver nanoparticles
obtained by chemical synthesis. The latter are obtained upon reaction of sodium
borohydride with silver nitrate AgNO 3 .
Unlike PLAL nanoparticles, no β-sheets are detected after the interaction with Ag
NPs CHEM . This different behavior could be attributed to a weak interaction between
Ag NPs CHEM and hIAPP responsible for a feeble Raman enhancement.
Specifically, in chemical synthesized silver colloids, borohydride anions are
adsorbed onto nanoparticles surface. The presence of the resulting repelling forces
plays a key role in the hIAPP-colloid interaction.
In summary, we have shown that uncapped and pure NPs produced by ablation in water exhibit highest sensitivity if compared with chemically produced ones
and inhibit the structural arrangements of monomers and oligomers into a β-sheet
structures, characteristic of fibrils [65].
4.3.2 Environmental Applications: Dye Removal,
Antibacterial Activity, and Photocatalytic H 2
Production
Environmental pollution, energy production, and storage are current global challenges faced by human beings. Since the past two decades, the evolution of nanotechnology represents an ever-improving process in the design, discovery, creation, and
G. Compagnini et al.
Fig. 4.9 SERS spectra of hIAPP (250 nM) in presence of Ag and Au NPs PLAL after an incubation
time of 4 h
Figure 4.9 reports the same experiment conducted using silver nanoparticles
obtained by chemical synthesis. The latter are obtained upon reaction of sodium
borohydride with silver nitrate AgNO 3 .
Unlike PLAL nanoparticles, no β-sheets are detected after the interaction with Ag
NPs CHEM . This different behavior could be attributed to a weak interaction between
Ag NPs CHEM and hIAPP responsible for a feeble Raman enhancement.
Specifically, in chemical synthesized silver colloids, borohydride anions are
adsorbed onto nanoparticles surface. The presence of the resulting repelling forces
plays a key role in the hIAPP-colloid interaction.
In summary, we have shown that uncapped and pure NPs produced by ablation in water exhibit highest sensitivity if compared with chemically produced ones
and inhibit the structural arrangements of monomers and oligomers into a β-sheet
structures, characteristic of fibrils [65].
4.3.2 Environmental Applications: Dye Removal,
Antibacterial Activity, and Photocatalytic H 2
Production
Environmental pollution, energy production, and storage are current global challenges faced by human beings. Since the past two decades, the evolution of nanotechnology represents an ever-improving process in the design, discovery, creation, and