23 Asymmetric Catalysis and Chromatographic …
495
OH
OH
(R)13
Cu(NO 3 ) 2
(R)-MOF-13
CO 2 H
CO 2 H
Fig. 23.7 X-ray structure of (R)-MOF-13
23.4 Conclusions
In this review, we summarize the recent progress in synthesis of novel chiral MOFs
and their applications as heterogeneous catalysts in asymmetric reactions and as
the chiral stationary phase of HPLC. Chiral MOFs have proven to be remarkable
heterogeneous catalysts in asymmetric reactions affording high yields and excellent
enantioselectivities of reactions comparable with those of homogeneous catalysts.
Chromatographic separation with chiral MOFs has rapidly expanded in recent years,
and more suitable chiral MOFs will be designed for separation of various organic
racemates in the near future.
495
OH
OH
(R)13
Cu(NO 3 ) 2
(R)-MOF-13
CO 2 H
CO 2 H
Fig. 23.7 X-ray structure of (R)-MOF-13
23.4 Conclusions
In this review, we summarize the recent progress in synthesis of novel chiral MOFs
and their applications as heterogeneous catalysts in asymmetric reactions and as
the chiral stationary phase of HPLC. Chiral MOFs have proven to be remarkable
heterogeneous catalysts in asymmetric reactions affording high yields and excellent
enantioselectivities of reactions comparable with those of homogeneous catalysts.
Chromatographic separation with chiral MOFs has rapidly expanded in recent years,
and more suitable chiral MOFs will be designed for separation of various organic
racemates in the near future.