494
K. Tanaka
Fig. 23.6 (continued)
1-phenyl-1-propanol, benzoin, ketoprofen, and naproxen), and it showed excellent performance in enantioseparation. Cui et al. [23] reported two homochiral
1,10-biphenol-based MOFs with chiral dihydroxyl and dimethoxy groups, respectively. A MOF containing chiral dihydroxyl auxiliaries was used as the chiral
stationary phase of HPLC for enantioseparation of 1-phenylethylamine, 1-(4fluorophenyl)ethylamine, 1-phenylpropylamine, and 1-naphthalen-1-yl-ethylamine.
In 2019, Tanaka et al. [24] reported a new homochiral MOF (R)-MOF-13 with
an expanded open cage (10.7 Å × 10.7 Å) (Fig. 23.7) based on the (R)-3,3’-bis(6carboxy-2-naphthyl)-2,2’-dihydroxy-1,1’-binaphthyl ligand and used it as a novel
chiral stationary phase for HPLC. (R)-MOF-13 showed excellent performance for
enantiomeric separation of several racemates, including sec-alcohols, sulfoxides,
epoxides, lactone, 1,3-dioxolan-2-one, and oxazolidinone, in HPLC (Fig. 23.8).
K. Tanaka
Fig. 23.6 (continued)
1-phenyl-1-propanol, benzoin, ketoprofen, and naproxen), and it showed excellent performance in enantioseparation. Cui et al. [23] reported two homochiral
1,10-biphenol-based MOFs with chiral dihydroxyl and dimethoxy groups, respectively. A MOF containing chiral dihydroxyl auxiliaries was used as the chiral
stationary phase of HPLC for enantioseparation of 1-phenylethylamine, 1-(4fluorophenyl)ethylamine, 1-phenylpropylamine, and 1-naphthalen-1-yl-ethylamine.
In 2019, Tanaka et al. [24] reported a new homochiral MOF (R)-MOF-13 with
an expanded open cage (10.7 Å × 10.7 Å) (Fig. 23.7) based on the (R)-3,3’-bis(6carboxy-2-naphthyl)-2,2’-dihydroxy-1,1’-binaphthyl ligand and used it as a novel
chiral stationary phase for HPLC. (R)-MOF-13 showed excellent performance for
enantiomeric separation of several racemates, including sec-alcohols, sulfoxides,
epoxides, lactone, 1,3-dioxolan-2-one, and oxazolidinone, in HPLC (Fig. 23.8).