460
Y. Kageyama
Thus, while strategies for creating such dynamics at the molecular level have not
been successful to date, recent efforts to construct a multi-molecular motor system
appear to be a promising approach for attaining a working molecular system in the
near feature.
Acknowledgements The author deeply appreciates to Professor Sadamu Takeda, Dr. Tomonori
Ikegami, and Dr. Hiroyasu Sato for their collaboration. The work was supported by JSPS KAKENHI
Grant Number JP17H05247 in Scientific Research on Innovative Areas “Photosynergetics”, JSPS
KAKENHI Grant Number JP18H05423, and JST PRESTO Grant Number JPMJPR13K6.
References
1. Kay ER, Leigh DA, Zerbetto F (2007) Synthetic molecular motors and mechanical machines.
Angew Chem Int Ed 46:72–191
2. von Delius M, Leigh DA (2011) Walking molecules. Chem Soc Rev 40:3656–3676
3. Kassem S, van Leeuwen T, Lubbe AS, Wilson MR, Feringa BL, Leigh DA (2017) Artificial
molecular motors. Chem Soc Rev 46:2592–2621
4. Koumura N, Zijlstra RWJ, van Delden RA, Harada N, Feringa BL (1999) Light-driven
monodirectional molecular rotor. Nature 401:152–155
5. Feringa BL (2001) In control of motion: from molecular switches to molecular motors. Acc
Chem Res 34:504–513
6. ter Wiel MKJ, van Delden RA, Meetsma A, Feringa BL (2003) Increased speed of rotation for
the smallest light-driven molecular motor. J Am Chem Soc 125:15076–15086
7. van Delden RA, Koumura N, Schoevaars A, Meetsma A, Feringa BL (2003) A donor–acceptor
substituted molecular motor: unidirectional rotation driven by visible light. Org Biomol Chem
1:33–35
8. Vicario J, Walko M, Meetsma A, Feringa BL (2006) Fine tuning of the rotary motion by
structural modification in light-driven unidirectional molecular motors. J Am Chem Soc
128:5127–5135
9. Wezenberg SJ, Feringa BL (2018) Supramolecularly directed rotary motion in a photoresponsive receptor. Nat Commun 9:1984
10. Ragazzon G, Baroncini M, Silvi S, Venturi M, Credi A (2014) Light-powered autonomous
and directional molecular motion of a dissipative self-assembling system. Nat Nanotechnol
10:70–75
11. Yu J-J, Zhao L-Y, Shi Z-T, Zhang Q, London G, Liang W-J, Gao C, Li M-M, Cao X-M, Tian
H, Feringa BL, Qu D-H (2019) Pumping a ring-sliding molecular motion by a light-powered
molecular motor. J Org Chem 84:5790–5802
12. Pezzato C, Nguyen MT, Kim DJ, Anamimoghadam O, Mosca L, Stoddart JF (2018) Controlling
dual molecular pumps electrochemically. Angew Chem Int Ed 57:9325–9329
13. Cheng C, McGonigal PR, Schneebeli ST, Li H, Vermeulen NA, Ke C, Stoddart JF (2015) An
artificial molecular pump. Nat Nanotechnol 10:547–553
14. Kudernac T, Ruangsupapichat N, Parschau M, Maciá B, Katsonis N, Harutyunyan SR, Ernst
K-H, Feringa BL (2011) Electrically driven directional motion of a four-wheeled molecule on
a metal surface. Nature 479:208–211
15. Collins BSL, Kistemaker JCM, Otten E, Feringa BL (2016) A chemically powered unidirectional rotary molecular motor based on a palladium redox cycle. Nat Chem 8:860–866
16. Wilson MR, Solà J, Carlone A, Goldup SM, Lebrasseur N, Leigh DA (2016) An autonomous
chemically fuelled small-molecule motor. Nature 534:235–240
17. Fletcher SP, Dumur F, Pollard MM, Feringa BL (2005) A reversible, unidirectional molecular
rotary motor driven by chemical energy. Science 310:80–82
Y. Kageyama
Thus, while strategies for creating such dynamics at the molecular level have not
been successful to date, recent efforts to construct a multi-molecular motor system
appear to be a promising approach for attaining a working molecular system in the
near feature.
Acknowledgements The author deeply appreciates to Professor Sadamu Takeda, Dr. Tomonori
Ikegami, and Dr. Hiroyasu Sato for their collaboration. The work was supported by JSPS KAKENHI
Grant Number JP17H05247 in Scientific Research on Innovative Areas “Photosynergetics”, JSPS
KAKENHI Grant Number JP18H05423, and JST PRESTO Grant Number JPMJPR13K6.
References
1. Kay ER, Leigh DA, Zerbetto F (2007) Synthetic molecular motors and mechanical machines.
Angew Chem Int Ed 46:72–191
2. von Delius M, Leigh DA (2011) Walking molecules. Chem Soc Rev 40:3656–3676
3. Kassem S, van Leeuwen T, Lubbe AS, Wilson MR, Feringa BL, Leigh DA (2017) Artificial
molecular motors. Chem Soc Rev 46:2592–2621
4. Koumura N, Zijlstra RWJ, van Delden RA, Harada N, Feringa BL (1999) Light-driven
monodirectional molecular rotor. Nature 401:152–155
5. Feringa BL (2001) In control of motion: from molecular switches to molecular motors. Acc
Chem Res 34:504–513
6. ter Wiel MKJ, van Delden RA, Meetsma A, Feringa BL (2003) Increased speed of rotation for
the smallest light-driven molecular motor. J Am Chem Soc 125:15076–15086
7. van Delden RA, Koumura N, Schoevaars A, Meetsma A, Feringa BL (2003) A donor–acceptor
substituted molecular motor: unidirectional rotation driven by visible light. Org Biomol Chem
1:33–35
8. Vicario J, Walko M, Meetsma A, Feringa BL (2006) Fine tuning of the rotary motion by
structural modification in light-driven unidirectional molecular motors. J Am Chem Soc
128:5127–5135
9. Wezenberg SJ, Feringa BL (2018) Supramolecularly directed rotary motion in a photoresponsive receptor. Nat Commun 9:1984
10. Ragazzon G, Baroncini M, Silvi S, Venturi M, Credi A (2014) Light-powered autonomous
and directional molecular motion of a dissipative self-assembling system. Nat Nanotechnol
10:70–75
11. Yu J-J, Zhao L-Y, Shi Z-T, Zhang Q, London G, Liang W-J, Gao C, Li M-M, Cao X-M, Tian
H, Feringa BL, Qu D-H (2019) Pumping a ring-sliding molecular motion by a light-powered
molecular motor. J Org Chem 84:5790–5802
12. Pezzato C, Nguyen MT, Kim DJ, Anamimoghadam O, Mosca L, Stoddart JF (2018) Controlling
dual molecular pumps electrochemically. Angew Chem Int Ed 57:9325–9329
13. Cheng C, McGonigal PR, Schneebeli ST, Li H, Vermeulen NA, Ke C, Stoddart JF (2015) An
artificial molecular pump. Nat Nanotechnol 10:547–553
14. Kudernac T, Ruangsupapichat N, Parschau M, Maciá B, Katsonis N, Harutyunyan SR, Ernst
K-H, Feringa BL (2011) Electrically driven directional motion of a four-wheeled molecule on
a metal surface. Nature 479:208–211
15. Collins BSL, Kistemaker JCM, Otten E, Feringa BL (2016) A chemically powered unidirectional rotary molecular motor based on a palladium redox cycle. Nat Chem 8:860–866
16. Wilson MR, Solà J, Carlone A, Goldup SM, Lebrasseur N, Leigh DA (2016) An autonomous
chemically fuelled small-molecule motor. Nature 534:235–240
17. Fletcher SP, Dumur F, Pollard MM, Feringa BL (2005) A reversible, unidirectional molecular
rotary motor driven by chemical energy. Science 310:80–82