lignin, fatty acids, humid materials and amino acids. The drugs and their metabolites
found in both aquatic environments and human fluids are given in Tables 9.6
and 9.7.
The metabolites of cocaine are norecgonidine methyl ester, ecgonidine, mhydroxyl-benzoylecgonine and p-hydroxyl-benzoylecgonine, and methamphetamine conjugates. Degradation studies have been carried out on the degradation of
Table 9.6 Human drug metabolites found in the aquatic environment
Compound
Human metabolites identified
Amphetamine
Amphetamine
3, 4-Methylenedioxyamphetamine
Methylenedioxymethamphetamine
Methylenedioxyethylamphetamine
Methylbenzodioxolylbutanamine
Methamphetamine
p-Hydroxy-methamphetamine
Cannabinoids
Δ
9
-Tetrahydrocannabinol
Hydroxyl-tetrahydrocannabinol – conjugate
Nor-9-carboxy-Δ9-tetrahydrocannabinol – glucuronide
Δ
9
-Tetrahydrocannabinol-9-carboxylic acid
Cocaine
Benzoylecgonine
Cocaethylene
Cocaine
Ecgonidine
Ecgonidine methyl ester
Ecgonine
Ecgonine methyl ester
m-OH-benzoylecgonine
Norecgonine methyl ester
Norcocaine
Norecgonidine
LSD
2-Oxo-3-hydroxy-lysergic diethylamide
Hydroxyl lysergic diethylamide
Iso-lysergic diethylamide
Lysergic diethylamide
Nor-lysergic diethylamide
Opiates
6-Monoacetylmorphine
Heroin
Morphine
Normorphine
Morphine-3-glucuronide
Methadone
2-Ethylene-1,5-dimethyl-1-3,3-diphenylpyrrolidine
Ethyl morphine
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