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Italian aquatic environment. J Hazard Mater 179:1042–1048
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biological degradation of the pharmaceutical compounds clofibric acid, ibuprofen, and
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3 Existence of Antibiotics in Wastewater as a Pollution Indicator
69
(ed) Chemistry in water reuse, 1st edn. Ann Arbour Science, Ann Arbor, pp 55–99
Walsh C (2003) Antibiotics: actions, origins, resistance, 1st edn. ASM Press, Washington, DC, p
345
Watkinson A, Murby E, Costanzo S (2007) Removal of antibiotics in conventional and advanced
wastewater treatment: implications for environmental discharge and wastewater recycling.
Water Res 41:4164–4176
Weber KP, Petersen EJ, Bissegger S et al (2014) Effect of gold nanoparticles and ciprofloxacin on
microbial catabolism: a community-based approach. Environ Toxicol Chem 33:44–51
White D, Cox E (2013) Fighting the impact of antibiotic-resistance. FDA Consumer Health
Information. www.fda.gov/downloads/. . ./UCM350090.pdf. Accessed 4 Sept 2016
WHO (2019) Essential medicine and Health products. https://www.who.int/medicines/news/2019/
WHO_releases2019AWaRe_classification_antibiotics/en/
Wu G, Liu Z, Chen T et al (2015) Elevation-dependent variations of tree growth and intrinsic wateruse efficiency in Schrenk spruce (Picea schrenkiana) in the western Tianshan Mountains. China
Front Plant Sci 6:309. https://doi.org/10.3389/fpls.2015.00309
Xie X, Zhou Q, Bao Q et al (2011) Genotoxicity of tetracycline as an emerging pollutant on root
meristem cells of wheat (Triticum Aestivum L.). Environ Toxicol 26:417–423. https://doi.org/
10.1002/tox.20567
Xu WH, Zhang G, Zou SC et al (2007) Determination of selected antibiotics in the Victoria Harbour
and the Pearl River, South China using high performance liquid chromatography–electrospray
ionization tandem mass spectrometry. Environ Pollut 145:672–679
Xu J, Xu Y, Wang H et al (2015) Occurrence of antibiotics and antibiotic resistance genes in a
sewage treatment plant and its effluent-receiving river. Chemosphere 119:1379–1385
Yang QX, Zhang J, Zhu KF et al (2009) Influence of oxytetracycline on the structure and activity of
microbial community in wheat rhizosphere soil. J Environ Sci 21:954–959
Yang Y, Li B, Zou S et al (2014) Fate of antibiotic resistance genes in sewage treatment plant
revealed by metagenomic approach. Water Res 62:97–106
Yaronskaya EB, Gritskevich ER, Trukhanovets NL et al (2007) Effects of kinetin on early stages of
chlorophyll biosynthesis in streptomycin-treated barley seedling. Russ J Plant Physiol
54:388–395
Yasojima M, Nakada N, Komori K et al (2006) Occurrence of levofloxacin, clarithromycin and
azithromycin in wastewater treatment plant in Japan. Water Sci Technol 53:227
Yiruhan Y, Wang Q, Mo C et al (2010) Determination of four fluoroquinolone antibiotics in tap
water in Guangzhou and Macao. Environ Pollut 158:2350–2358
Yoneyama H, Katsumata R (2006) Antibiotic resistance in bacteria and its future for novel
antibiotic development. Biosci Biotechnol Biochem 70:1060–1075
Zhang D, Lin L, Luo Z et al (2011) Occurrence of selected antibiotics in Jiulongjiang River in
various seasons, South China. J Environ Monit 13:1953–1960. https://doi.org/10.1039/
c0em00765j
Zhang CH, Tang JW, Wang LL et al (2015) Occurrence of antibiotics in water and sediment from
Zizhuyuan Lake. Pol J Environ Stud 24(4):1831–1836
Zhengqi Y, Weinberg HS, Meyer MT (2004) Occurrence of antibiotics in drinking water. The
University of North Carolina at Chapel Hill U.S. Geological Survey Kansas p 138–142
Zhou L, Ying G, Liu S et al (2013) Occurrence and fate of eleven classes of antibiotics in two
typical wastewater treatment plants in South China. Sci Total Environ 452–453:365–376
Zuccato E, Castiglioni S, Bagnati R et al (2010) Source, occurrence and fate of antibiotics in the
Italian aquatic environment. J Hazard Mater 179:1042–1048
Zwiener C, Frimmel F (2003) Short-term testes with a pilot sewage plant and biofilm reactors for the
biological degradation of the pharmaceutical compounds clofibric acid, ibuprofen, and
diclofenac. Sci Total Environ 309:201–211
3 Existence of Antibiotics in Wastewater as a Pollution Indicator
69