Calderon CB, Sabundayo BP (2007) Antimicrobial classifications: drugs for bugs. In: Schwalbe R,
Steele-Moore L, Goodwin AC (eds) Antimicrobial susceptibility testing protocols. CRC Press/
Taylor and Frances Group. ISBN 978-0-8247-4100-6
Carballa M, Omil F, Lema JM et al (2004) Behavior of pharmaceuticals, cosmetics and hormones in
a sewage treatment plant. Water Res 38:2918–2926
Carvalho IT, Santos L (2016) Antibiotics in the aquatic environments: a review of the European
scenario. Environ Int 94:736–757
Cermak L, Kopecky J, Novotna J et al (2008) Bacterial communities of two contrasting soils reacted
differently to lincomycin treatment. Appl Soil Ecol 40:348–358
Cha JM, Yang S, Carlson KH (2006) Trace determination of B-lactam antibiotics in surface water
and urban wastewater using liquid chromatography combined with electrospray tandem mass
spectrometry. J Chromatogr A 1115:46–57. https://doi.org/10.1016/j.chroma.2006.02.086
Chen H, Zhang M (2013) Occurrence and removal of antibiotic resistance genes in municipal
wastewater and rural domestic sewage treatment systems in eastern China. Environ Int 55:9–14
Choquet-Kastylevsky G, Vial T, Descotes J (2002) Allergic adverse reactions to sulfonamides. Curr
Allergy Asthma Rep 2:16–25
Christian T, Schneider RJ, Färber HA et al (2003) Determination of antibiotic residues in manure,
soil, and surface waters. Acta Hydrochim Hydrobiol 31:36–44. https://doi.org/10.1002/aheh.
200390014
Cordova-Kreylos AL, Scow KM (2007) Effects of ciprofloxacin on salt marsh sediment microbial
communities. ISME J 1:585–595
Cui H, Wang SP, Fu J et al (2014) Influence of ciprofloxacin onmicrobial community structure and
function in soils. Biol Fertil Soils 50:939–947
DeJongh CM, Kooij PJF, de Voogt P et al (2012) Screening and human health risk assessment of
pharmaceuticals and their transformation products in Dutch surface waters and drinking water.
Sci Total Environ 427:70–77
Demoling LA, Baath E (2008) No long-term persistence of bacterial pollution-induced community
tolerance in tylosin-polluted soil. Environ Sci Technol 42:6917–6921
Demoling LA, Baath E, Greve G et al (2009) Effects of sulfamethoxazole on soil microbial
communities after adding substrate. Soil Biol Biochem 41:840–848
Diaz-Cruz M, Lopez de Alda M, Barcelo D (2003) Environmental behaviour and analysis of
veterinary and human drugs in soils, sedimnets and sludge. TrAC Trends Anal Chem 22:340
Díaz-Cruz MS, García-Galán MJ, Barceló D (2008) Highly sensitive simultaneous determination of
sulfonamide antibiotics and one metabolite in environmental waters by liquid chromatography–
quadrupole linear ion trap–mass spectrometry. J Chromatogr A 1193:50–59. https://doi.org/10.
1016/j.chroma.2008.03.029
Diehl DL, Lapara TME (2010) Effect of temperature on the fate of genes encoding tetracycline
resistance and the integrase of class 1 integrons within anaerobic and aerobic digesters treating
municipal wastewater solids. Environ Sci Technol 44:9128–9133
Dolliver H, Gupta S (2008) Antibiotic losses in leaching and surface runoff from manure-amended
agricultural land. J Environ Qual 37:1227–1237
Dong L, Gao J, Xie X et al (2012) DNA damage and biochemical toxicity of antibiotics in soil on
the earthworm Eiseniafetida. Chemosphere 89:44–51
ECDC (2015) (European Centre for Disease Prevention and Control), EFSA (European Food Safety
Authority) and EMA (European Medicines Agency). ECDC/EFSA/EMA first joint report on the
integrated analysis of the consumption of antimicrobial agents and occurrence of antimicrobial
resistance in bacteria from humans and food producing animals. EFSA J 13:4006. P114 http://
www.efsa.europa.eu/sites/default/files/scientific_output/files/main_documents/4006.pdf.
Accessed January 2017
Eggen T, Asp TN, Grave K et al (2011) Uptake and translocation of metformin, ciprofloxacin and
narsin in forage and crop plants. Chemosphere 85:26–33
Eguchi K, Nagase H, Ozawa M et al (2004) Evaluation of antimicrobial agents for veterinary use in
the ecotoxicity test using microalgae. Chemosphere 57:1733–1738
3 Existence of Antibiotics in Wastewater as a Pollution Indicator
61
Steele-Moore L, Goodwin AC (eds) Antimicrobial susceptibility testing protocols. CRC Press/
Taylor and Frances Group. ISBN 978-0-8247-4100-6
Carballa M, Omil F, Lema JM et al (2004) Behavior of pharmaceuticals, cosmetics and hormones in
a sewage treatment plant. Water Res 38:2918–2926
Carvalho IT, Santos L (2016) Antibiotics in the aquatic environments: a review of the European
scenario. Environ Int 94:736–757
Cermak L, Kopecky J, Novotna J et al (2008) Bacterial communities of two contrasting soils reacted
differently to lincomycin treatment. Appl Soil Ecol 40:348–358
Cha JM, Yang S, Carlson KH (2006) Trace determination of B-lactam antibiotics in surface water
and urban wastewater using liquid chromatography combined with electrospray tandem mass
spectrometry. J Chromatogr A 1115:46–57. https://doi.org/10.1016/j.chroma.2006.02.086
Chen H, Zhang M (2013) Occurrence and removal of antibiotic resistance genes in municipal
wastewater and rural domestic sewage treatment systems in eastern China. Environ Int 55:9–14
Choquet-Kastylevsky G, Vial T, Descotes J (2002) Allergic adverse reactions to sulfonamides. Curr
Allergy Asthma Rep 2:16–25
Christian T, Schneider RJ, Färber HA et al (2003) Determination of antibiotic residues in manure,
soil, and surface waters. Acta Hydrochim Hydrobiol 31:36–44. https://doi.org/10.1002/aheh.
200390014
Cordova-Kreylos AL, Scow KM (2007) Effects of ciprofloxacin on salt marsh sediment microbial
communities. ISME J 1:585–595
Cui H, Wang SP, Fu J et al (2014) Influence of ciprofloxacin onmicrobial community structure and
function in soils. Biol Fertil Soils 50:939–947
DeJongh CM, Kooij PJF, de Voogt P et al (2012) Screening and human health risk assessment of
pharmaceuticals and their transformation products in Dutch surface waters and drinking water.
Sci Total Environ 427:70–77
Demoling LA, Baath E (2008) No long-term persistence of bacterial pollution-induced community
tolerance in tylosin-polluted soil. Environ Sci Technol 42:6917–6921
Demoling LA, Baath E, Greve G et al (2009) Effects of sulfamethoxazole on soil microbial
communities after adding substrate. Soil Biol Biochem 41:840–848
Diaz-Cruz M, Lopez de Alda M, Barcelo D (2003) Environmental behaviour and analysis of
veterinary and human drugs in soils, sedimnets and sludge. TrAC Trends Anal Chem 22:340
Díaz-Cruz MS, García-Galán MJ, Barceló D (2008) Highly sensitive simultaneous determination of
sulfonamide antibiotics and one metabolite in environmental waters by liquid chromatography–
quadrupole linear ion trap–mass spectrometry. J Chromatogr A 1193:50–59. https://doi.org/10.
1016/j.chroma.2008.03.029
Diehl DL, Lapara TME (2010) Effect of temperature on the fate of genes encoding tetracycline
resistance and the integrase of class 1 integrons within anaerobic and aerobic digesters treating
municipal wastewater solids. Environ Sci Technol 44:9128–9133
Dolliver H, Gupta S (2008) Antibiotic losses in leaching and surface runoff from manure-amended
agricultural land. J Environ Qual 37:1227–1237
Dong L, Gao J, Xie X et al (2012) DNA damage and biochemical toxicity of antibiotics in soil on
the earthworm Eiseniafetida. Chemosphere 89:44–51
ECDC (2015) (European Centre for Disease Prevention and Control), EFSA (European Food Safety
Authority) and EMA (European Medicines Agency). ECDC/EFSA/EMA first joint report on the
integrated analysis of the consumption of antimicrobial agents and occurrence of antimicrobial
resistance in bacteria from humans and food producing animals. EFSA J 13:4006. P114 http://
www.efsa.europa.eu/sites/default/files/scientific_output/files/main_documents/4006.pdf.
Accessed January 2017
Eggen T, Asp TN, Grave K et al (2011) Uptake and translocation of metformin, ciprofloxacin and
narsin in forage and crop plants. Chemosphere 85:26–33
Eguchi K, Nagase H, Ozawa M et al (2004) Evaluation of antimicrobial agents for veterinary use in
the ecotoxicity test using microalgae. Chemosphere 57:1733–1738
3 Existence of Antibiotics in Wastewater as a Pollution Indicator
61