60. Pacia MZ, Mateuszuk L, Chlopicki S, Baranska M, Kaczor A (2015) Biochemical changes
of the endothelium in the murine model of NO-deficient hypertension. Analyst 140:2178–
2184
61. Schulz H, Baranska M (2007) Identification and quantification of valuable plant substances
by IR and Raman spectroscopy. Vib Spectrosc 43:13–25
62. Czamara K, Majzner K, Pacia MZ, Kochan K, Kaczor A, Baranska M (2015) Raman
spectroscopy of lipids: a review. J Raman Spectrosc 46:4–20
63. Byrne HJ, Baranska M, Puppels GJ, Stone N, Wood B, Gough KM, Lasch P, Heraud P,
Sulé-Susoj J, Sockalingum GD (2015) Spectropathology for the next generation: quo vadis?
Analyst 140:2066–2073
64. Aird WC (2007) Phenotypic heterogeneity of the endothelium: I. Structure, function, and
mechanisms. Circ Res 100:158–173
65. Bouis D, Hospers GAP, Meijer C, Molema G, Mulder NH (2001) Endothelium in vitro: a
review of human vascular endothelial cell lines for blood vessel-related research.
Angiogenesis 4:91–102
66. Aird WC (2003) Endothelial cell heterogeneity. Crit Care Med 31:S221–S230
67. Wilson SE, Lloyd SA, He YG, McCash CS (1993) Extended life of human corneal
endothelial cells transfected with the SV40 large T antigen. Invest Ophthalmol Vis Sci
34:2112–2123
68. Edgell CJ, McDonald CC, Graham JB (1983) Permanent cell line expressing human factor
VIII-related antigen established by hybridization. Proc Natl Acad Sci 80:3734–3737
69. Ades E, Candal F, Swerlick R, George VG, Summers S, Bosse DC, Lawley TJ (1992)
HMEC-1: establishment of an immortalized human microvascular endothelial cell line.
J Invest Dermatol 99:683–690
70. Lidington EA, Moyes DL, McCormack AM, Rose ML (1999) A comparison of primary
endothelial cells and endothelial cell lines for studies of immune interactions. Transpl
Immunol 7:239–246
71. Baranska M, Kaczor A, Malek K, Jaworska A, Majzner K, Staniszewska-Slezak E,
Pacia MZ, Zajac G, Dybas J, Wiercigroch E (2015) Raman microscopy as a novel tool to
detect endothelial dysfunction. Pharmacol Reports 67:736–743
72. Pacia MZ, Buczek E, Blazejczyk A, Gregorius A, Wietrzyk J, Chlopicki Baranska M,
Kaczoret A (2016) 3D Raman imaging of systemic endothelial dysfunction in the murine
model of metastatic breast cancer. Anal Bioanal Chem 408:3381–3387
73. Pacia MZ, Mateuszuk L, Buczek E, Chlopicki S, Blazejczyk A, Wietrzyk A, Baranska M,
Kaczor A (2016) Rapid biochemical profiling of endothelial dysfunction in diabetes,
hypertension and cancer metastasis by hierarchical cluster analysis of Raman spectra.
J Raman Spectrosc 47:1310–1317
74. Pilarczyk M, Mateuszuk L, Rygula A, Kepczynski M, Chlopicki S, Baranska M, Kaczor A
(2014) Endothelium in spots—high-content imaging of lipid rafts clusters in db/db mice.
PLoS ONE 9:e106065
75. Pilarczyk M, Rygula A, Mateuszuk L, Chlopicki S, Baranska M, Kaczor A (2013)
Multi-methodological insight into the vessel wall cross-section: Raman and AFM imaging
combined with immunohistochemical staining. Biomed Spectrosc Imaging 2:191–197
76. Rygula A, Pacia MZ, Mateuszuk L, Kaczor A, Kostogrys RB, Chlopicki S, Baranska M
(2015) Identification of a biochemical marker for endothelial dysfunction using Raman
spectroscopy. Analyst 140:2185–2189
77. Buschman HP, Marple ET, Wach ML, Bennett B, Bakker Schut TC, Bruining HA,
Bruschke AV, van der Laarse A, Puppels GJ (2000) In vivo determination of the molecular
composition of artery wall by intravascular Raman spectroscopy. Anal Chem 72:3771–3775
78. Wang HW, Le TT, Cheng JX (2008) Label-free imaging of arterial cells and extracellular
matrix using a multimodal CARS microscope. Opt Commun 281:1813–1822
79. Majzner K, Kaczor A, Kachamakova-Trojanowska N, Fedorowicz A, Chlopicki S,
Baranska M (2013) 3D confocal Raman imaging of endothelial cells and vascular wall:
perspectives in analytical spectroscopy of biomedical research. Analyst 138:603–610
6 Small and Large Molecules Investigated by Raman Spectroscopy
191
of the endothelium in the murine model of NO-deficient hypertension. Analyst 140:2178–
2184
61. Schulz H, Baranska M (2007) Identification and quantification of valuable plant substances
by IR and Raman spectroscopy. Vib Spectrosc 43:13–25
62. Czamara K, Majzner K, Pacia MZ, Kochan K, Kaczor A, Baranska M (2015) Raman
spectroscopy of lipids: a review. J Raman Spectrosc 46:4–20
63. Byrne HJ, Baranska M, Puppels GJ, Stone N, Wood B, Gough KM, Lasch P, Heraud P,
Sulé-Susoj J, Sockalingum GD (2015) Spectropathology for the next generation: quo vadis?
Analyst 140:2066–2073
64. Aird WC (2007) Phenotypic heterogeneity of the endothelium: I. Structure, function, and
mechanisms. Circ Res 100:158–173
65. Bouis D, Hospers GAP, Meijer C, Molema G, Mulder NH (2001) Endothelium in vitro: a
review of human vascular endothelial cell lines for blood vessel-related research.
Angiogenesis 4:91–102
66. Aird WC (2003) Endothelial cell heterogeneity. Crit Care Med 31:S221–S230
67. Wilson SE, Lloyd SA, He YG, McCash CS (1993) Extended life of human corneal
endothelial cells transfected with the SV40 large T antigen. Invest Ophthalmol Vis Sci
34:2112–2123
68. Edgell CJ, McDonald CC, Graham JB (1983) Permanent cell line expressing human factor
VIII-related antigen established by hybridization. Proc Natl Acad Sci 80:3734–3737
69. Ades E, Candal F, Swerlick R, George VG, Summers S, Bosse DC, Lawley TJ (1992)
HMEC-1: establishment of an immortalized human microvascular endothelial cell line.
J Invest Dermatol 99:683–690
70. Lidington EA, Moyes DL, McCormack AM, Rose ML (1999) A comparison of primary
endothelial cells and endothelial cell lines for studies of immune interactions. Transpl
Immunol 7:239–246
71. Baranska M, Kaczor A, Malek K, Jaworska A, Majzner K, Staniszewska-Slezak E,
Pacia MZ, Zajac G, Dybas J, Wiercigroch E (2015) Raman microscopy as a novel tool to
detect endothelial dysfunction. Pharmacol Reports 67:736–743
72. Pacia MZ, Buczek E, Blazejczyk A, Gregorius A, Wietrzyk J, Chlopicki Baranska M,
Kaczoret A (2016) 3D Raman imaging of systemic endothelial dysfunction in the murine
model of metastatic breast cancer. Anal Bioanal Chem 408:3381–3387
73. Pacia MZ, Mateuszuk L, Buczek E, Chlopicki S, Blazejczyk A, Wietrzyk A, Baranska M,
Kaczor A (2016) Rapid biochemical profiling of endothelial dysfunction in diabetes,
hypertension and cancer metastasis by hierarchical cluster analysis of Raman spectra.
J Raman Spectrosc 47:1310–1317
74. Pilarczyk M, Mateuszuk L, Rygula A, Kepczynski M, Chlopicki S, Baranska M, Kaczor A
(2014) Endothelium in spots—high-content imaging of lipid rafts clusters in db/db mice.
PLoS ONE 9:e106065
75. Pilarczyk M, Rygula A, Mateuszuk L, Chlopicki S, Baranska M, Kaczor A (2013)
Multi-methodological insight into the vessel wall cross-section: Raman and AFM imaging
combined with immunohistochemical staining. Biomed Spectrosc Imaging 2:191–197
76. Rygula A, Pacia MZ, Mateuszuk L, Kaczor A, Kostogrys RB, Chlopicki S, Baranska M
(2015) Identification of a biochemical marker for endothelial dysfunction using Raman
spectroscopy. Analyst 140:2185–2189
77. Buschman HP, Marple ET, Wach ML, Bennett B, Bakker Schut TC, Bruining HA,
Bruschke AV, van der Laarse A, Puppels GJ (2000) In vivo determination of the molecular
composition of artery wall by intravascular Raman spectroscopy. Anal Chem 72:3771–3775
78. Wang HW, Le TT, Cheng JX (2008) Label-free imaging of arterial cells and extracellular
matrix using a multimodal CARS microscope. Opt Commun 281:1813–1822
79. Majzner K, Kaczor A, Kachamakova-Trojanowska N, Fedorowicz A, Chlopicki S,
Baranska M (2013) 3D confocal Raman imaging of endothelial cells and vascular wall:
perspectives in analytical spectroscopy of biomedical research. Analyst 138:603–610
6 Small and Large Molecules Investigated by Raman Spectroscopy
191