Topics in Current Chemistry (2020) 378:8
1 3
49. Wang W, Gaus K, Tilley RD, Gooding JJ (2019) The impact of nanoparticle shape on cellular internalisation and transport: what do the different analysis methods tell us? Mater Horizons
6:1538–1547. https ://doi.org/10.1039/C9MH0 0664H
50. Fernandes R, Smyth NR, Muskens OL et al (2015) Interactions of skin with gold nanoparticles
of different surface charge, shape, and functionality. Small 11:713–721. https ://doi.org/10.1002/
smll.20140 1913
51. Tak YK, Pal S, Naoghare PK et al (2015) Shape-dependent skin penetration of silver nanoparticles: does it really matter? Sci Rep 5:16908. https ://doi.org/10.1038/srep1 6908
52. Turkevich J, Kim G (1970) Palladium: preparation and catalytic properties of particles of uniform size. Science 169:873–879. https ://doi.org/10.1126/scien ce.169.3948.873
53. Kimling J, Maier M, Okenve B et al (2006) Turkevich method for gold nanoparticle synthesis
revisited. J Phys Chem B 110:15700–15707. https ://doi.org/10.1021/jp061 667w
54. Labouta HI, Liu DC, Lin LL et al (2011) Gold nanoparticle penetration and reduced metabolism
in human skin by toluene. Pharm Res 28:2931–2944. https ://doi.org/10.1007/s1109 5-011-0561-z
55. Labouta HI, El-Khordagui LK, Kraus T, Schneider M (2011) Mechanism and determinants of
nanoparticle penetration through human skin. Nanoscale 3:4989. https ://doi.org/10.1039/c1nr1
1109d
56. Huang Y, Yu F, Park Y-S et al (2010) Co-administration of protein drugs with gold nanoparticles
to enable percutaneous delivery. Biomaterials 31:9086–9091. https ://doi.org/10.1016/j.bioma
teria ls.2010.08.046
57. Hong S, Bielinska AU, Mecke A et al (2004) Interaction of poly(amidoamine) dendrimers with
supported lipid bilayers and cells: hole formation and the relation to transport. Bioconjug Chem
15:774–782. https ://doi.org/10.1021/bc049 962b
58. Kirjavainen M, Urtti A, Jääskeläinen I et al (1996) Interaction of liposomes with human skin
in vitro—the influence of lipid composition and structure. Biochim Biophys Acta Lipids Lipid
Metab 1304:179–189. https ://doi.org/10.1016/S0005 -2760(96)00126 -9
59. Shanmugam S, Song C-K, Nagayya-Sriraman S et al (2009) Physicochemical characterization
and skin permeation of liposome formulations containing clindamycin phosphate. Arch Pharm
Res 32:1067–1075. https ://doi.org/10.1007/s1227 2-009-1713-0
60. Lee O, Jeong SH, Shin WU et al (2013) Influence of surface charge of gold nanorods on skin
penetration. Ski Res Technol 19:e390–e396. https ://doi.org/10.1111/j.1600-0846.2012.00656 .x
61. Mahmoud NN, Al-Qaoud KM, Al-Bakri AG et al (2016) Colloidal stability of gold nanorod
solution upon exposure to excised human skin: effect of surface chemistry and protein adsorption. Int J Biochem Cell Biol 75:223–231. https ://doi.org/10.1016/j.bioce l.2016.02.020
62. Hao F, Jin X, Liu QS et al (2017) Epidermal penetration of gold nanoparticles and its underlying mechanism based on human reconstructed 3D episkin model. ACS Appl Mater Interfaces
9:42577–42588. https ://doi.org/10.1021/acsam i.7b137 00
63. Suk JS, Xu Q, Kim N et al (2016) PEGylation as a strategy for improving nanoparticlebased drug and gene delivery. Adv Drug Deliv Rev 99:28–51. https ://doi.org/10.1016/j.
addr.2015.09.012
64. Tsai H-C, Hsiao PF, Peng S et al (2016) Enhancing the in vivo transdermal delivery of gold nanoparticles using poly(ethylene glycol) and its oleylamine conjugate. Int J Nanomed 11:1867–1878.
https ://doi.org/10.2147/IJN.S1025 99
65. Mahmoud NN, Alkilany AM, Dietrich D et al (2017) Preferential accumulation of gold nanorods
into human skin hair follicles: effect of nanoparticle surface chemistry. J Colloid Interface Sci
503:95–102. https ://doi.org/10.1016/j.jcis.2017.05.011
66. Labala S, Mandapalli PK, Kurumaddali A, Venuganti VVK (2015) Layer-by-layer polymer coated
gold nanoparticles for topical delivery of imatinib mesylate to treat melanoma. Mol Pharm 12:878–
888. https ://doi.org/10.1021/mp500 7163
67. Bessar H, Venditti I, Benassi L et al (2016) Functionalized gold nanoparticles for topical delivery
of methotrexate for the possible treatment of psoriasis. Colloids Surf B Biointerfaces 141:141–147.
https ://doi.org/10.1016/j.colsu rfb.2016.01.021
68. Pan A, Zhong M, Wu H et al (2018) Topical application of keratinocyte growth factor conjugated
gold nanoparticles accelerate wound healing. Nanomed Nanotechnol Biol Med 14:1619–1628. https
://doi.org/10.1016/j.nano.2018.04.007
69. Niu J, Chu Y, Huang Y-F et al (2017) Transdermal gene delivery by functional peptide-conjugated
cationic gold nanoparticle reverses the progression and metastasis of cutaneous melanoma. ACS
Appl Mater Interfaces 9:9388–9401. https ://doi.org/10.1021/acsam i.6b163 78
234
Reprinted from the journal
1 3
49. Wang W, Gaus K, Tilley RD, Gooding JJ (2019) The impact of nanoparticle shape on cellular internalisation and transport: what do the different analysis methods tell us? Mater Horizons
6:1538–1547. https ://doi.org/10.1039/C9MH0 0664H
50. Fernandes R, Smyth NR, Muskens OL et al (2015) Interactions of skin with gold nanoparticles
of different surface charge, shape, and functionality. Small 11:713–721. https ://doi.org/10.1002/
smll.20140 1913
51. Tak YK, Pal S, Naoghare PK et al (2015) Shape-dependent skin penetration of silver nanoparticles: does it really matter? Sci Rep 5:16908. https ://doi.org/10.1038/srep1 6908
52. Turkevich J, Kim G (1970) Palladium: preparation and catalytic properties of particles of uniform size. Science 169:873–879. https ://doi.org/10.1126/scien ce.169.3948.873
53. Kimling J, Maier M, Okenve B et al (2006) Turkevich method for gold nanoparticle synthesis
revisited. J Phys Chem B 110:15700–15707. https ://doi.org/10.1021/jp061 667w
54. Labouta HI, Liu DC, Lin LL et al (2011) Gold nanoparticle penetration and reduced metabolism
in human skin by toluene. Pharm Res 28:2931–2944. https ://doi.org/10.1007/s1109 5-011-0561-z
55. Labouta HI, El-Khordagui LK, Kraus T, Schneider M (2011) Mechanism and determinants of
nanoparticle penetration through human skin. Nanoscale 3:4989. https ://doi.org/10.1039/c1nr1
1109d
56. Huang Y, Yu F, Park Y-S et al (2010) Co-administration of protein drugs with gold nanoparticles
to enable percutaneous delivery. Biomaterials 31:9086–9091. https ://doi.org/10.1016/j.bioma
teria ls.2010.08.046
57. Hong S, Bielinska AU, Mecke A et al (2004) Interaction of poly(amidoamine) dendrimers with
supported lipid bilayers and cells: hole formation and the relation to transport. Bioconjug Chem
15:774–782. https ://doi.org/10.1021/bc049 962b
58. Kirjavainen M, Urtti A, Jääskeläinen I et al (1996) Interaction of liposomes with human skin
in vitro—the influence of lipid composition and structure. Biochim Biophys Acta Lipids Lipid
Metab 1304:179–189. https ://doi.org/10.1016/S0005 -2760(96)00126 -9
59. Shanmugam S, Song C-K, Nagayya-Sriraman S et al (2009) Physicochemical characterization
and skin permeation of liposome formulations containing clindamycin phosphate. Arch Pharm
Res 32:1067–1075. https ://doi.org/10.1007/s1227 2-009-1713-0
60. Lee O, Jeong SH, Shin WU et al (2013) Influence of surface charge of gold nanorods on skin
penetration. Ski Res Technol 19:e390–e396. https ://doi.org/10.1111/j.1600-0846.2012.00656 .x
61. Mahmoud NN, Al-Qaoud KM, Al-Bakri AG et al (2016) Colloidal stability of gold nanorod
solution upon exposure to excised human skin: effect of surface chemistry and protein adsorption. Int J Biochem Cell Biol 75:223–231. https ://doi.org/10.1016/j.bioce l.2016.02.020
62. Hao F, Jin X, Liu QS et al (2017) Epidermal penetration of gold nanoparticles and its underlying mechanism based on human reconstructed 3D episkin model. ACS Appl Mater Interfaces
9:42577–42588. https ://doi.org/10.1021/acsam i.7b137 00
63. Suk JS, Xu Q, Kim N et al (2016) PEGylation as a strategy for improving nanoparticlebased drug and gene delivery. Adv Drug Deliv Rev 99:28–51. https ://doi.org/10.1016/j.
addr.2015.09.012
64. Tsai H-C, Hsiao PF, Peng S et al (2016) Enhancing the in vivo transdermal delivery of gold nanoparticles using poly(ethylene glycol) and its oleylamine conjugate. Int J Nanomed 11:1867–1878.
https ://doi.org/10.2147/IJN.S1025 99
65. Mahmoud NN, Alkilany AM, Dietrich D et al (2017) Preferential accumulation of gold nanorods
into human skin hair follicles: effect of nanoparticle surface chemistry. J Colloid Interface Sci
503:95–102. https ://doi.org/10.1016/j.jcis.2017.05.011
66. Labala S, Mandapalli PK, Kurumaddali A, Venuganti VVK (2015) Layer-by-layer polymer coated
gold nanoparticles for topical delivery of imatinib mesylate to treat melanoma. Mol Pharm 12:878–
888. https ://doi.org/10.1021/mp500 7163
67. Bessar H, Venditti I, Benassi L et al (2016) Functionalized gold nanoparticles for topical delivery
of methotrexate for the possible treatment of psoriasis. Colloids Surf B Biointerfaces 141:141–147.
https ://doi.org/10.1016/j.colsu rfb.2016.01.021
68. Pan A, Zhong M, Wu H et al (2018) Topical application of keratinocyte growth factor conjugated
gold nanoparticles accelerate wound healing. Nanomed Nanotechnol Biol Med 14:1619–1628. https
://doi.org/10.1016/j.nano.2018.04.007
69. Niu J, Chu Y, Huang Y-F et al (2017) Transdermal gene delivery by functional peptide-conjugated
cationic gold nanoparticle reverses the progression and metastasis of cutaneous melanoma. ACS
Appl Mater Interfaces 9:9388–9401. https ://doi.org/10.1021/acsam i.6b163 78
234
Reprinted from the journal