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Topics in Current Chemistry (2020) 378:35
Table 1
Fluorescence quantum dot-based lateral flow assays
HAU
Hemagglutinating units, IU
international units, QDs
quantum dots
a
DNA strand displacement amplification
Analyte(s)
Quantum dot
Assay format
Assay time/limit of detection Real sample
Reference
Heart fatty acid binding protein
CdTe
Sandwich immunoassay 15 min/221 pg mL
−1
Human serum
[120]
C-reactive protein (CRP)
Interleukin-6 (IL-6)
CdTe
Sandwich immunoassay 30 min/0.3 μg mL
−1
(CRP)
0.9 pg mL
−1
(IL-6)
Human serum
[121]
Carcinoembryonic antigen (CEA)
CdSe/ZnS
Sandwich immunoassay 15 min/0.049 ng mL
−1
Human serum
[122]
Glutathione
CdSe@ZnS
Displacement assay
10 min/25 nM
HeLa cells extract samples [123]
Gastric cancer carbohydrate antigen 72-4
CdSe/ZnS
Sandwich immunoassay 10 min/2 IU mL
−1
Human serum
[124]
Human immunodeficiency virus-DNA
CdTe
SDA
a
15 min/0.76 pM
Human serum
[125]
Influenza A nucleoprotein
605-nm QDs
Sandwich immunoassay 1.5 fmol
–
[126]
Simultaneous alpha fetoprotein (AFP) and carcinoembryonic antigen (CEA)
546-nm QDs
620-nm QDs
Sandwich immunoassay 15 min/3 ng mL
−1
(AFP)
2 ng mL
−1
(CEA)
Human serum
[127]
Simultaneous influenza A virus subtypes H5 and H9 CdSe/ZnS QDs Sandwich immunoassay 15 min/0.016 HAU (H5)
0.25 HAU (H9)
Human serum
[128]
155
Reprinted from the journal