Topics in Current Chemistry (2019) 377:1
1 3
4.2 Derivatives of Levulinic Acid
Alkyl levulinates have attacted great interest as biobased fuel additives. They also
have potential applications in the perfume and flavor industries [106]. Kong et al.
evaluated cerium salt of phosphotungstic acid supported on silica gel pellets as a
heterogeneous catalyst for the continuous flow esterification of ethanol with lev‑
ulinic acid (8). Compound 8 was injected as an ethanol solution, and quantitative
selectivity as well as 99% conversion were maintained for 50 h upon operation
Fig. 35 Two‑step sequential continuous flow process for the synthesis of solketal tert‑butyl ether (60)
136
Reprinted from the journal
1 3
4.2 Derivatives of Levulinic Acid
Alkyl levulinates have attacted great interest as biobased fuel additives. They also
have potential applications in the perfume and flavor industries [106]. Kong et al.
evaluated cerium salt of phosphotungstic acid supported on silica gel pellets as a
heterogeneous catalyst for the continuous flow esterification of ethanol with lev‑
ulinic acid (8). Compound 8 was injected as an ethanol solution, and quantitative
selectivity as well as 99% conversion were maintained for 50 h upon operation
Fig. 35 Two‑step sequential continuous flow process for the synthesis of solketal tert‑butyl ether (60)
136
Reprinted from the journal