1.2 C–H Activation
11
intermediate. Next, the oxidation of Pd
II to Pd
IV is facilitated by the
stoichiometric oxidant. The catalyst is regenerated via a C–X bond forming
reductive elimination, releasing the oxidised product. Both an intramolecular
elimination and an intermolecular nucleophilic substitution can facilitate the
C–X bond formation.
[3]