18. Qian X, Xu Z (2015) Fluorescence imaging of metal ions implicated in diseases. Chem Soc
Rev 44(14):4487–4493
19. Fernández A, Vendrell M (2016) Smart fluorescent probes for imaging macrophageactivity.
Chem Soc Rev 45(5):1182–1196
20. Li X, Gao X, Shi W, Ma H (2014) Design strategies for water-soluble small molecular
chromogenic and fluorogenic probes. Chem Rev 114(1):590–659
21. Yang Z, Sharma A, Qi J, Peng X, Lee DY, Hu R, Lin D, Qu J, Kim JS (2016) Super-resolution
fluorescent materials: an insight into design and bioimaging applications. Chem Soc Rev 45
(17):4651–4667
22. Yang Z, Cao J, He Y, Yang JH, Kim T, Peng X, Kim JS (2014) MacroÀ/micro-environmentsensitive chemosensing and biological imaging. Chem Soc Rev 43(13):4563–4601
23. Liu K, Kong X, Ma Y, Lin W (2017) Rational design of a robust fluorescent probe for the
detection of endogenous carbon monoxide in living zebrafish embryos and mouse tissue.
Angew Chem Int Ed Engl 56(43):13489–13492
24. Ling X, Zhang S, Shao P, Li W, Yang L, Ding Y, Xu C, Stella N, Bai M (2015) A novel nearinfrared fluorescence imaging probe that preferentially binds to cannabinoid receptors CB2R
over CB1R. Biomaterials 57:169–178
25. Deutscher SL (2010) Phage display in molecular imaging and diagnosis of cancer. Chem Rev
110(5):3196–3211
26. Kobayashi H, Ogawa M, Alford R, Choyke PL, Urano Y (2010) New strategies for fluorescent
probe design in medical diagnostic imaging. Chem Rev 110(5):2620–2640
27. Smith AM, Mancini MC, Nie S (2009) Bioimaging: second window for in vivo imaging.
Nat Nanotechnol 4(11):710–7111
28. Hong G, Diao S, Antaris AL, Dai H (2015) Carbon nanomaterials for biological imaging and
nanomedicinal therapy. Chem Rev 115(19):10816–10906
29. Welsher K, Liu Z, Sherlock SP, Robinson JT, Chen Z, Daranciang D, Dai H (2009) A route to
brightly fluorescent carbon nanotubes for near-infrared imaging in mice. Nat Nanotechnol 4
(11):773–780
30. Diao S, Blackburn JL, Hong G, Antaris AL, Chang J, Wu JZ, Zhang B, Cheng K, Kuo CJ, Dai
H (2015) Fluorescence imaging in vivo at wavelengths beyond 1500 nm. Angew Chem Int Ed
Engl 54(49):14758–14762
31. Antaris AL, Chen H, Cheng K, Sun Y, Hong G, Qu C, Diao S, Deng Z, Hu X, Zhang B,
Zhang X, Yaghi OK, Alamparambil ZR, Hong X, Cheng Z, Dai HJ (2016) A small-molecule
dye for NIR-II imaging. Nat Mater 15(2):235–242
32. Jiang YX, Ding BB, Xiao YL, Xing L, Hong XC, Cheng Z (2016) Novel benzo-bis(1,2,5thiadiazole) fluorophores for in vivo NIR-II imaging of cancer. Chem Sci 7(9):6203–6207
33. Yang Q, Hu Z, Zhu S, Ma R, Ma H, Ma Z, Wan H, Zhu T, Jiang Z, Liu W, Jiao L, Sun H,
Liang Y, Dai H (2018) Donor engineering for NIR-II molecular fluorophores with enhanced
fluorescent performance. J Am Chem Soc 140(5):1715–1724
34. Céspedes-Guirao FJ, Ropero AB, Font-Sanchis E, Nadal Á, Fernández-Lázaro F, SastreSanto Á (2011) A water-soluble perylene dye functionalised with a 17β-estradiol: a new
fluorescent tool for steroid hormones. Chem Commun 47(29):8307–8309
35. Rickert EL, Oriana S, Hartman-Frey C, Long X, Webb TT, Nephew KP, Weatherman RV
(2010) Synthesis and characterization of fluorescent 4-hydroxytamoxifen conjugates with
unique antiestrogenic properties. Bioconjug Chem 21(5):903–910
36. Yang L, Hu ZY, Luo JJ, Tang C, Zhang SL, Ning WT, Dong C, Huang J, Liu XJ, Zhou HB
(2017) Dual functional small molecule fluorescent probes for image-guided estrogen receptorspecific targeting coupled potent antiproliferative potency for breast cancer therapy. Bioorg
Med Chem 25(13):3531–3539
37. Levi J, Cheng Z, Gheysens O, Patel M, Chan CT, Wang Y, Namavari M, Gambhir SS (2007)
Fluorescent fructose derivatives for imaging breast cancer cells. Bioconjug Chem 18
(3):628–634
26
J. Tian et al.
Rev 44(14):4487–4493
19. Fernández A, Vendrell M (2016) Smart fluorescent probes for imaging macrophageactivity.
Chem Soc Rev 45(5):1182–1196
20. Li X, Gao X, Shi W, Ma H (2014) Design strategies for water-soluble small molecular
chromogenic and fluorogenic probes. Chem Rev 114(1):590–659
21. Yang Z, Sharma A, Qi J, Peng X, Lee DY, Hu R, Lin D, Qu J, Kim JS (2016) Super-resolution
fluorescent materials: an insight into design and bioimaging applications. Chem Soc Rev 45
(17):4651–4667
22. Yang Z, Cao J, He Y, Yang JH, Kim T, Peng X, Kim JS (2014) MacroÀ/micro-environmentsensitive chemosensing and biological imaging. Chem Soc Rev 43(13):4563–4601
23. Liu K, Kong X, Ma Y, Lin W (2017) Rational design of a robust fluorescent probe for the
detection of endogenous carbon monoxide in living zebrafish embryos and mouse tissue.
Angew Chem Int Ed Engl 56(43):13489–13492
24. Ling X, Zhang S, Shao P, Li W, Yang L, Ding Y, Xu C, Stella N, Bai M (2015) A novel nearinfrared fluorescence imaging probe that preferentially binds to cannabinoid receptors CB2R
over CB1R. Biomaterials 57:169–178
25. Deutscher SL (2010) Phage display in molecular imaging and diagnosis of cancer. Chem Rev
110(5):3196–3211
26. Kobayashi H, Ogawa M, Alford R, Choyke PL, Urano Y (2010) New strategies for fluorescent
probe design in medical diagnostic imaging. Chem Rev 110(5):2620–2640
27. Smith AM, Mancini MC, Nie S (2009) Bioimaging: second window for in vivo imaging.
Nat Nanotechnol 4(11):710–7111
28. Hong G, Diao S, Antaris AL, Dai H (2015) Carbon nanomaterials for biological imaging and
nanomedicinal therapy. Chem Rev 115(19):10816–10906
29. Welsher K, Liu Z, Sherlock SP, Robinson JT, Chen Z, Daranciang D, Dai H (2009) A route to
brightly fluorescent carbon nanotubes for near-infrared imaging in mice. Nat Nanotechnol 4
(11):773–780
30. Diao S, Blackburn JL, Hong G, Antaris AL, Chang J, Wu JZ, Zhang B, Cheng K, Kuo CJ, Dai
H (2015) Fluorescence imaging in vivo at wavelengths beyond 1500 nm. Angew Chem Int Ed
Engl 54(49):14758–14762
31. Antaris AL, Chen H, Cheng K, Sun Y, Hong G, Qu C, Diao S, Deng Z, Hu X, Zhang B,
Zhang X, Yaghi OK, Alamparambil ZR, Hong X, Cheng Z, Dai HJ (2016) A small-molecule
dye for NIR-II imaging. Nat Mater 15(2):235–242
32. Jiang YX, Ding BB, Xiao YL, Xing L, Hong XC, Cheng Z (2016) Novel benzo-bis(1,2,5thiadiazole) fluorophores for in vivo NIR-II imaging of cancer. Chem Sci 7(9):6203–6207
33. Yang Q, Hu Z, Zhu S, Ma R, Ma H, Ma Z, Wan H, Zhu T, Jiang Z, Liu W, Jiao L, Sun H,
Liang Y, Dai H (2018) Donor engineering for NIR-II molecular fluorophores with enhanced
fluorescent performance. J Am Chem Soc 140(5):1715–1724
34. Céspedes-Guirao FJ, Ropero AB, Font-Sanchis E, Nadal Á, Fernández-Lázaro F, SastreSanto Á (2011) A water-soluble perylene dye functionalised with a 17β-estradiol: a new
fluorescent tool for steroid hormones. Chem Commun 47(29):8307–8309
35. Rickert EL, Oriana S, Hartman-Frey C, Long X, Webb TT, Nephew KP, Weatherman RV
(2010) Synthesis and characterization of fluorescent 4-hydroxytamoxifen conjugates with
unique antiestrogenic properties. Bioconjug Chem 21(5):903–910
36. Yang L, Hu ZY, Luo JJ, Tang C, Zhang SL, Ning WT, Dong C, Huang J, Liu XJ, Zhou HB
(2017) Dual functional small molecule fluorescent probes for image-guided estrogen receptorspecific targeting coupled potent antiproliferative potency for breast cancer therapy. Bioorg
Med Chem 25(13):3531–3539
37. Levi J, Cheng Z, Gheysens O, Patel M, Chan CT, Wang Y, Namavari M, Gambhir SS (2007)
Fluorescent fructose derivatives for imaging breast cancer cells. Bioconjug Chem 18
(3):628–634
26
J. Tian et al.
