16. Ding M, Chen Y, Guan WJ, Zhong CH, Jiang M, Luo WZ, Chen XB, Tang CL, Tang Y, Jian
QM et al (2016) Measuring airway remodeling in patients with different COPD staging using
endobronchial optical coherence tomography. Chest 150(6):1281–1290
17. Gora MJ, Simmons LH, Queneherve L, Grant CN, Carruth RW, Lu W, Tiernan A, Dong J,
Walker-Corkery B, Soomro A et al (2016) Tethered capsule endomicroscopy: from bench to
bedside at a primary care practice. J Biomed Opt 21(10):104001
18. Rotondano G, Bianco MA, Sansone S, Prisco A, Meucci C, Garofano ML, Cipolletta L (2012)
Trimodal endoscopic imaging for the detection and differentiation of colorectal adenomas: a
prospective single-centre clinical evaluation. Int J Color Dis 27(3):331–336
19. Bergholt MS, Lin K, Wang J, Zheng W, Xu H, Huang Q, Ren JL, Ho KY, Teh M, Srivastava S
et al (2016) Simultaneous fingerprint and high-wavenumber fiber-optic Raman spectroscopy
enhances real-time in vivo diagnosis of adenomatous polyps during colonoscopy.
J Biophotonics 9(4):333–342
20. Wang J, Lin K, Zheng W, Ho KY, Teh M, Yeoh KG, Huang Z (2015) Comparative study of the
endoscope-based bevelled and volume fiber-optic Raman probes for optical diagnosis of gastric
dysplasia in vivo at endoscopy. Anal Bioanal Chem 407(27):8303–8310
21. Ming LC, Gangodu NR, Loh T, Zheng W, Wang J, Lin K, Zhiwei H (2017) Real time nearinfrared Raman spectroscopy for the diagnosis of nasopharyngeal cancer. Oncotarget 8
(30):49443–49450
22. Kothapalli SR, Liu H, Liao JC, Cheng Z, Gambhir SS (2012) Endoscopic imaging of Cerenkov
luminescence. Biomed Opt Express 3(6):1215–1225
23. Friedland S, Benaron D, Parachikov I, Soetikno R (2003) Measurement of mucosal capillary
hemoglobin oxygen saturation in the colon by reflectance spectrophotometry. Gastrointest
Endosc 57(4):492–497
24. Friedland S, Benaron D, Coogan S, Sze DY, Soetikno R (2007) Diagnosis of chronic mesenteric
ischemia by visible light spectroscopy during endoscopy. Gastrointest Endosc 65(2):294–300
25. Meng G, Liang Y, Sarsfield S, Jiang WC, Lu R, Dudman JT, Aponte Y, Ji N (2019)
High-throughput synapse-resolving two-photon fluorescence microendoscopy for deep-brain
volumetric imaging in vivo. elife 8
26. Bocarsly ME, Jiang WC, Wang C, Dudman JT, Ji N, Aponte Y (2015) Minimally invasive
microendoscopy system for in vivo functional imaging of deep nuclei in the mouse brain.
Biomed Opt Express 6(11):4546–4556
27. Weissleder R, Pittet MJ (2008) Imaging in the era of molecular oncology. Nature 452
(7187):580–589
28. Keereweer S, Kerrebijn JD, van Driel PB, Xie B, Kaijzel EL, Snoeks TJ, Que I, Hutteman M,
van der Vorst JR, Mieog JS et al (2011) Optical image-guided surgery – where do we stand?
Mol Imaging Biol 13(2):199–207
29. Rosenthal EL, Warram JM, de Boer E, Basilion JP, Biel MA, Bogyo M, Bouvet M,
Brigman BE, Colson YL, DeMeester SR et al (2016) Successful translation of fluorescence
navigation during oncologic surgery: a consensus report. J Nucl Med 57(1):144–150
30. Mondal SB, Gao S, Zhu N, Liang R, Gruev V, Achilefu S (2014) Real-time fluorescence imageguided oncologic surgery. Adv Cancer Res 124:171–211
31. Haque R, Contreras R, McNicoll MP, Eckberg EC, Petitti DB (2006) Surgical margins and
survival after head and neck cancer surgery. BMC Ear Nose Throat Disord 6:2
32. Eldeeb H, Macmillan C, Elwell C, Hammod A (2012) The effect of the surgical margins on the
outcome of patients with head and neck squamous cell carcinoma: single institution experience.
Cancer Biol Med 9(1):29–33
33. Pirro V, Alfaro CM, Jarmusch AK, Hattab EM, Cohen-Gadol AA, Cooks RG (2017)
Intraoperative assessment of tumor margins during glioma resection by desorption electrospray
ionization-mass spectrometry. Proc Natl Acad Sci U S A 114(26):6700–6705
34. Sawabata N, Ohta M, Matsumura A, Nakagawa K, Hirano H, Maeda H, Matsuda H, Thoracic
Surgery Study Group of Osaka U (2004) Optimal distance of malignant negative margin in
excision of nonsmall cell lung cancer: a multicenter prospective study. Ann Thorac Surg 77
(2):415–420
220
E. P. Stater et al.
QM et al (2016) Measuring airway remodeling in patients with different COPD staging using
endobronchial optical coherence tomography. Chest 150(6):1281–1290
17. Gora MJ, Simmons LH, Queneherve L, Grant CN, Carruth RW, Lu W, Tiernan A, Dong J,
Walker-Corkery B, Soomro A et al (2016) Tethered capsule endomicroscopy: from bench to
bedside at a primary care practice. J Biomed Opt 21(10):104001
18. Rotondano G, Bianco MA, Sansone S, Prisco A, Meucci C, Garofano ML, Cipolletta L (2012)
Trimodal endoscopic imaging for the detection and differentiation of colorectal adenomas: a
prospective single-centre clinical evaluation. Int J Color Dis 27(3):331–336
19. Bergholt MS, Lin K, Wang J, Zheng W, Xu H, Huang Q, Ren JL, Ho KY, Teh M, Srivastava S
et al (2016) Simultaneous fingerprint and high-wavenumber fiber-optic Raman spectroscopy
enhances real-time in vivo diagnosis of adenomatous polyps during colonoscopy.
J Biophotonics 9(4):333–342
20. Wang J, Lin K, Zheng W, Ho KY, Teh M, Yeoh KG, Huang Z (2015) Comparative study of the
endoscope-based bevelled and volume fiber-optic Raman probes for optical diagnosis of gastric
dysplasia in vivo at endoscopy. Anal Bioanal Chem 407(27):8303–8310
21. Ming LC, Gangodu NR, Loh T, Zheng W, Wang J, Lin K, Zhiwei H (2017) Real time nearinfrared Raman spectroscopy for the diagnosis of nasopharyngeal cancer. Oncotarget 8
(30):49443–49450
22. Kothapalli SR, Liu H, Liao JC, Cheng Z, Gambhir SS (2012) Endoscopic imaging of Cerenkov
luminescence. Biomed Opt Express 3(6):1215–1225
23. Friedland S, Benaron D, Parachikov I, Soetikno R (2003) Measurement of mucosal capillary
hemoglobin oxygen saturation in the colon by reflectance spectrophotometry. Gastrointest
Endosc 57(4):492–497
24. Friedland S, Benaron D, Coogan S, Sze DY, Soetikno R (2007) Diagnosis of chronic mesenteric
ischemia by visible light spectroscopy during endoscopy. Gastrointest Endosc 65(2):294–300
25. Meng G, Liang Y, Sarsfield S, Jiang WC, Lu R, Dudman JT, Aponte Y, Ji N (2019)
High-throughput synapse-resolving two-photon fluorescence microendoscopy for deep-brain
volumetric imaging in vivo. elife 8
26. Bocarsly ME, Jiang WC, Wang C, Dudman JT, Ji N, Aponte Y (2015) Minimally invasive
microendoscopy system for in vivo functional imaging of deep nuclei in the mouse brain.
Biomed Opt Express 6(11):4546–4556
27. Weissleder R, Pittet MJ (2008) Imaging in the era of molecular oncology. Nature 452
(7187):580–589
28. Keereweer S, Kerrebijn JD, van Driel PB, Xie B, Kaijzel EL, Snoeks TJ, Que I, Hutteman M,
van der Vorst JR, Mieog JS et al (2011) Optical image-guided surgery – where do we stand?
Mol Imaging Biol 13(2):199–207
29. Rosenthal EL, Warram JM, de Boer E, Basilion JP, Biel MA, Bogyo M, Bouvet M,
Brigman BE, Colson YL, DeMeester SR et al (2016) Successful translation of fluorescence
navigation during oncologic surgery: a consensus report. J Nucl Med 57(1):144–150
30. Mondal SB, Gao S, Zhu N, Liang R, Gruev V, Achilefu S (2014) Real-time fluorescence imageguided oncologic surgery. Adv Cancer Res 124:171–211
31. Haque R, Contreras R, McNicoll MP, Eckberg EC, Petitti DB (2006) Surgical margins and
survival after head and neck cancer surgery. BMC Ear Nose Throat Disord 6:2
32. Eldeeb H, Macmillan C, Elwell C, Hammod A (2012) The effect of the surgical margins on the
outcome of patients with head and neck squamous cell carcinoma: single institution experience.
Cancer Biol Med 9(1):29–33
33. Pirro V, Alfaro CM, Jarmusch AK, Hattab EM, Cohen-Gadol AA, Cooks RG (2017)
Intraoperative assessment of tumor margins during glioma resection by desorption electrospray
ionization-mass spectrometry. Proc Natl Acad Sci U S A 114(26):6700–6705
34. Sawabata N, Ohta M, Matsumura A, Nakagawa K, Hirano H, Maeda H, Matsuda H, Thoracic
Surgery Study Group of Osaka U (2004) Optimal distance of malignant negative margin in
excision of nonsmall cell lung cancer: a multicenter prospective study. Ann Thorac Surg 77
(2):415–420
220
E. P. Stater et al.