36
This entire array is about the size of a single spot on a traditional spotted array.
(Adapted from Ref. [72B]).
Finally, it can be surmised that the described fiber optic microsphere-based biosensor is a versatile platform that possesses micro-scale features and an overall
array size that enables rapid analysis and extremely low detection limits. Redundant
detection elements in the array increase the signal-to-noise ratio and avoid the
potential for false-positive and false-negative results. Microsphere-based arrays are
reusable and are easy to fabricate. The fiber optic platform has also been applied to
other applications, including artificial olfaction and cell-based array sensing [66].
Fig. 2.18 Schematic diagram of the fiber optic imaging system. (Adapted from Ref. [72B])
J. H. Banoub and A. Mikhael
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