174
61. Caprioli RM, Farmer TB, Gile J (1997) Molecular imaging of biological samples: localization
of peptides and proteins using MALDI-TOF MS. Anal Chem 69(23):4751–4760
62. Solon EG, Schweitzer A, Stoeckli M, Prideaux B (2010) Autoradiography, MALDI-MS, and
SIMS-MS imaging in pharmaceutical discovery and development. AAPS J 12(1):11–26
63. Prideaux B, Stoeckli M (2012) Mass spectrometry imaging for drug distribution studies. J
Proteome 75(16):4999–5013
64. Cobice DF, Goodwin RJ, Andren PE, Nilsson A, Mackay CL, Andrew R (2015) Future technology insight: mass spectrometry imaging as a tool in drug research and development. Br J
Pharmacol 172(13):3266–3283
65. Arzuaga X, Smith MT, Gibbons CF, Skakkebaek NE, Yost EE, Beverly BEJ, Hotchkiss AK,
Hauser R, Pagani RL, Schrader SM, Zeise L, Prins GS (2019) Proposed key characteristics
of male reproductive toxicants as an approach for organizing and evaluating mechanistic evidence in human health Hazard assessments. Environ Health Perspect 127(6):65001
66. Lagarrigue M, Lavigne R, Tabet E, Genet V, Thome JP, Rondel K, Guevel B, Multigner L,
Samson M, Pineau C (2014) Localization and in situ absolute quantification of chlordecone in
the mouse liver by MALDI imaging. Anal Chem 86(12):5775–5783
67. Porta T, Lesur A, Varesio E, Hopfgartner G (2015) Quantification in MALDI-MS imaging:
what can we learn from MALDI-selected reaction monitoring and what can we expect for
imaging? Anal Bioanal Chem 407(8):2177–2187
68. Hauser R, Sokol R (2008) Science linking environmental contaminant exposures with fertility
and reproductive health impacts in the adult male. Fertil Steril 89(2 Suppl):e59–e65
69. Moline JM, Golden AL, Bar-Chama N, Smith E, Rauch ME, Chapin RE, Perreault SD,
Schrader SM, Suk WA, Landrigan PJ (2000) Exposure to hazardous substances and male
reproductive health: a research framework. Environ Health Perspect 108(9):803–813
70. Wong EW, Cheng CY (2011) Impacts of environmental toxicants on male reproductive dysfunction. Trends Pharmacol Sci 32(5):290–299
C. Pineau
61. Caprioli RM, Farmer TB, Gile J (1997) Molecular imaging of biological samples: localization
of peptides and proteins using MALDI-TOF MS. Anal Chem 69(23):4751–4760
62. Solon EG, Schweitzer A, Stoeckli M, Prideaux B (2010) Autoradiography, MALDI-MS, and
SIMS-MS imaging in pharmaceutical discovery and development. AAPS J 12(1):11–26
63. Prideaux B, Stoeckli M (2012) Mass spectrometry imaging for drug distribution studies. J
Proteome 75(16):4999–5013
64. Cobice DF, Goodwin RJ, Andren PE, Nilsson A, Mackay CL, Andrew R (2015) Future technology insight: mass spectrometry imaging as a tool in drug research and development. Br J
Pharmacol 172(13):3266–3283
65. Arzuaga X, Smith MT, Gibbons CF, Skakkebaek NE, Yost EE, Beverly BEJ, Hotchkiss AK,
Hauser R, Pagani RL, Schrader SM, Zeise L, Prins GS (2019) Proposed key characteristics
of male reproductive toxicants as an approach for organizing and evaluating mechanistic evidence in human health Hazard assessments. Environ Health Perspect 127(6):65001
66. Lagarrigue M, Lavigne R, Tabet E, Genet V, Thome JP, Rondel K, Guevel B, Multigner L,
Samson M, Pineau C (2014) Localization and in situ absolute quantification of chlordecone in
the mouse liver by MALDI imaging. Anal Chem 86(12):5775–5783
67. Porta T, Lesur A, Varesio E, Hopfgartner G (2015) Quantification in MALDI-MS imaging:
what can we learn from MALDI-selected reaction monitoring and what can we expect for
imaging? Anal Bioanal Chem 407(8):2177–2187
68. Hauser R, Sokol R (2008) Science linking environmental contaminant exposures with fertility
and reproductive health impacts in the adult male. Fertil Steril 89(2 Suppl):e59–e65
69. Moline JM, Golden AL, Bar-Chama N, Smith E, Rauch ME, Chapin RE, Perreault SD,
Schrader SM, Suk WA, Landrigan PJ (2000) Exposure to hazardous substances and male
reproductive health: a research framework. Environ Health Perspect 108(9):803–813
70. Wong EW, Cheng CY (2011) Impacts of environmental toxicants on male reproductive dysfunction. Trends Pharmacol Sci 32(5):290–299
C. Pineau