29. Nowak M, Selmar D (2016) Cellular distribution of alkaloids and their translocation via phloem
and xylem: the importance of compartment pH. Plant Biol 18:879–882
30. Yahyazadeh M, Nowak M, Kima H, Selmar D (2017) Horizontal natural product transfer:
a potential source of alkaloidal contaminants in phytopharmaceuticals. Phytomedicine 34:21–25
31. Hurtado C, Domínguez C, Pérez-Babace L, Cãnameras N, Comas J, Bayona JM (2016)
Estimate of uptake and translocation of emerging organic contaminants from irrigation water
concentration in lettuce grow under controlled conditions. J Hazard Mater 305:139–148
32. Werner C, Matile P (1985) Accumulation of coumarylglucosides in vacuoles of barley mesophyll protoplasts. J Plant Physiol 118:237–249
33. Lewerenz L (2016) Horizontaler Naturstoff-Transfer: Aufnahme von Farbstoffen in etiolierte
Keimlinge. Bachelor thesis, Faculty for Life Sciences, TU Braunschweig
34. Attia GY, Moussa MEM, Sheashea ER (2013) Characterization of red pigments extracted from
red beet (Beta vulgaris, L.) and its potential uses as antioxidant and natural food colorants.
Egypt J Agric Res 91:1095–1110
35. Herbach KM, Stintzing FC, Carle R (2006) Betalain stability and degradation – structural and
chromatic aspects. J Food Sci 71(4):R41–R50
36. Hijazin T, Radwan A, Abouzeid S, Dräger G, Selmar D (2019) Uptake and modification of
umbelliferone by various seedlings. Phytochem 157: 194-199
37. Nakano H, Nakajima E, Fujii Y, Yamada K, Shigemori H, Hasegawa K (2003) Leaching of the
allelopathic substance, L-tryptophan from the foliage of mesquite (Prosopis juliflora DC.) plants
by water spraying. Plant Growth Regul 40:49–52
38. Tukey HB (1970) The leaching of substances from plants. Annu Rev Plant Biol 21:305–324
39. Selmar D, Wittke C, Beck-von Wolffersdorff I, Klier B, Lewerenz L, Kleinwächter M, Nowak M
(2019) Horizontal Natural Product Transfer - a so far disregarded source of soil contaminations:
Interspecies transfer of pyrrolizidine alkaloids between living plants. subm. to Environ Pollut
40. Sandermann H (1994) Higher plant metabolism of xenobiotics: the ‘green liver’ concept.
Pharmacogenetics 4:225–241
41. Schaffner A, Messener B, Langebartels C, Sandermann H (2002) Genes and enzymes for inplanta phytoremediation of air, water and soil. Acta Biotechnol 22:141–151
42. Burken JG (2003) Uptake and metabolism of organic compounds: green-liver model.
In: McCutcheon SC, Schnoor JL (eds) Phytoremediation: transformation and control of contaminants. Wiley, New York
43. Ronczka S, These A, Bodi D, Preiß-Weigert A (2015) International collaborative study for the
determination of pyrrolizidine alkaloids in honey and herbal tea by SPE-LC-MS/MS. BfR
Wissenschat, Berlin
44. Cramer L, Schiebel H-M, Ernst L, Beuerle T (2013) Pyrrolizidine alkaloids in the food chain.
Development, validation, and application of a new HPLC-ESI-MS/MS sum parameter method.
J Agric Food Chem 61:11382–11391
45. Nowak M (2017) Horizontaler Naturstofftransfer: Nachweis und Grundlagen eines bislang
unbekannten Phänomens. Dissertation, Faculty of Life Sciences, TU Braunschweig
46. Furge LL, Guengerich FP (2006) Cytochrome P450 enzymes in drug metabolism and chemical
toxicology. Biochem Mol Biol Educ 34:66–74
47. Miners JO, Coulter S, Tukey RH, Veronese ME, Birkett DJ (1996) Cytochromes P450, 1A2,
and 2C9 are responsible for the human hepatic O-demethylation of R- and S-naproxen.
Biochem Pharmacol 51:1003–1008
48. Iovdijová A, Bencko V (2010) Potential risk of exposure to selected xenobiotic residues and
their fate in the food chain – part 1: classification of xenobiotics. Ann Agric Environ Med
17:183–192
49. Godheja J, Shekhar SK, Siddiqui SA, Dr M (2016) Xenobiotic compounds present in soil and
water: a review on remediation strategies. J Environ Anal Toxicol 6:5
50. Nowak M, Yahazadeh M, Lewerenz L, Selmar D (2017) Horizontal natural product transfer: a so
far unconsidered source of contamination of medicinal. In: Ghorbanpour M, Varma A (eds)
Environmental challenges and medicinal plants. Springer International Publishing AG, Switzerland
18 Horizontal Natural Product Transfer: A Novel Attribution in Allelopathy
439
and xylem: the importance of compartment pH. Plant Biol 18:879–882
30. Yahyazadeh M, Nowak M, Kima H, Selmar D (2017) Horizontal natural product transfer:
a potential source of alkaloidal contaminants in phytopharmaceuticals. Phytomedicine 34:21–25
31. Hurtado C, Domínguez C, Pérez-Babace L, Cãnameras N, Comas J, Bayona JM (2016)
Estimate of uptake and translocation of emerging organic contaminants from irrigation water
concentration in lettuce grow under controlled conditions. J Hazard Mater 305:139–148
32. Werner C, Matile P (1985) Accumulation of coumarylglucosides in vacuoles of barley mesophyll protoplasts. J Plant Physiol 118:237–249
33. Lewerenz L (2016) Horizontaler Naturstoff-Transfer: Aufnahme von Farbstoffen in etiolierte
Keimlinge. Bachelor thesis, Faculty for Life Sciences, TU Braunschweig
34. Attia GY, Moussa MEM, Sheashea ER (2013) Characterization of red pigments extracted from
red beet (Beta vulgaris, L.) and its potential uses as antioxidant and natural food colorants.
Egypt J Agric Res 91:1095–1110
35. Herbach KM, Stintzing FC, Carle R (2006) Betalain stability and degradation – structural and
chromatic aspects. J Food Sci 71(4):R41–R50
36. Hijazin T, Radwan A, Abouzeid S, Dräger G, Selmar D (2019) Uptake and modification of
umbelliferone by various seedlings. Phytochem 157: 194-199
37. Nakano H, Nakajima E, Fujii Y, Yamada K, Shigemori H, Hasegawa K (2003) Leaching of the
allelopathic substance, L-tryptophan from the foliage of mesquite (Prosopis juliflora DC.) plants
by water spraying. Plant Growth Regul 40:49–52
38. Tukey HB (1970) The leaching of substances from plants. Annu Rev Plant Biol 21:305–324
39. Selmar D, Wittke C, Beck-von Wolffersdorff I, Klier B, Lewerenz L, Kleinwächter M, Nowak M
(2019) Horizontal Natural Product Transfer - a so far disregarded source of soil contaminations:
Interspecies transfer of pyrrolizidine alkaloids between living plants. subm. to Environ Pollut
40. Sandermann H (1994) Higher plant metabolism of xenobiotics: the ‘green liver’ concept.
Pharmacogenetics 4:225–241
41. Schaffner A, Messener B, Langebartels C, Sandermann H (2002) Genes and enzymes for inplanta phytoremediation of air, water and soil. Acta Biotechnol 22:141–151
42. Burken JG (2003) Uptake and metabolism of organic compounds: green-liver model.
In: McCutcheon SC, Schnoor JL (eds) Phytoremediation: transformation and control of contaminants. Wiley, New York
43. Ronczka S, These A, Bodi D, Preiß-Weigert A (2015) International collaborative study for the
determination of pyrrolizidine alkaloids in honey and herbal tea by SPE-LC-MS/MS. BfR
Wissenschat, Berlin
44. Cramer L, Schiebel H-M, Ernst L, Beuerle T (2013) Pyrrolizidine alkaloids in the food chain.
Development, validation, and application of a new HPLC-ESI-MS/MS sum parameter method.
J Agric Food Chem 61:11382–11391
45. Nowak M (2017) Horizontaler Naturstofftransfer: Nachweis und Grundlagen eines bislang
unbekannten Phänomens. Dissertation, Faculty of Life Sciences, TU Braunschweig
46. Furge LL, Guengerich FP (2006) Cytochrome P450 enzymes in drug metabolism and chemical
toxicology. Biochem Mol Biol Educ 34:66–74
47. Miners JO, Coulter S, Tukey RH, Veronese ME, Birkett DJ (1996) Cytochromes P450, 1A2,
and 2C9 are responsible for the human hepatic O-demethylation of R- and S-naproxen.
Biochem Pharmacol 51:1003–1008
48. Iovdijová A, Bencko V (2010) Potential risk of exposure to selected xenobiotic residues and
their fate in the food chain – part 1: classification of xenobiotics. Ann Agric Environ Med
17:183–192
49. Godheja J, Shekhar SK, Siddiqui SA, Dr M (2016) Xenobiotic compounds present in soil and
water: a review on remediation strategies. J Environ Anal Toxicol 6:5
50. Nowak M, Yahazadeh M, Lewerenz L, Selmar D (2017) Horizontal natural product transfer: a so
far unconsidered source of contamination of medicinal. In: Ghorbanpour M, Varma A (eds)
Environmental challenges and medicinal plants. Springer International Publishing AG, Switzerland
18 Horizontal Natural Product Transfer: A Novel Attribution in Allelopathy
439