69. He Y, Langenhoff AAM, Sutton NB, Rijnaarts HHM, Blokland MH, Chen F, Huber C,
Schröder P (2017) Metabolism of ibuprofen by Phragmites australis: uptake and
phytodegradation. Environ Sci Technol 51:4576–4584
70. Kruve A, Kaupmees K, Liigand J, Leito I (2014) Negative electrospray ionization via
deprotonation: predicting the ionization efficiency. Anal Chem 86:4822–4830
71. Kruve A, Kaupmees K (2017) Predicting ESI/MS signal change for anions in different solvents.
Anal Chem 89:5079–5086
72. Wang T, Liigand J, Frandsen HL, Smedsgaard J, Kruve A (2020) Standard substances free
quantification makes LC/ESI/MS non-targeted screening of pesticides in cereals comparable
between labs. Food Chem 318:126460
73. Golan-Rozen N, Seiwert B, Riemenschneider C, Reemtsma T, Chefetz B, Hadar Y (2015)
Transformation pathways of the recalcitrant pharmaceutical compound carbamazepine by the
white-rot fungus pleurotus ostreatus: effects of growth conditions. Environ Sci Technol
49:12351–12362
74. Syranidou E, Christofilopoulos S, Gkavrou G, Thijs S, Weyens N, Vangronsveld J, Kalogerakis
N (2016) Exploitation of endophytic bacteria to enhance the phytoremediation potential of the
wetland helophyte Juncus acutus. Front Microbiol 7:1016
75. Bartha B, Huber C, Schröder P (2014) Uptake and metabolism of diclofenac in Typha latifolia –
how plants cope with human pharmaceutical pollution. Plant Sci 227:12–20
76. Kummerová M, Zezulka S, Babula P, Tříska J (2016) Possible ecological risk of two pharmaceuticals diclofenac and paracetamol demonstrated on a model plant Lemna minor. J Hazard
Mater 302:351–361
77. Pietrini F, Di Baccio D, Aceña J, Pérez S, Barceló D, Zacchini M (2015) Ibuprofen exposure in
Lemna gibba L.: evaluation of growth and phytotoxic indicators, detection of ibuprofen and
identification of its metabolites in plant and in the medium. J Hazard Mater 300:189–193
78. Santiago S, Roll DM, Ray C, Williams C, Moravcik P, Knopf A (2016) Effects of soil moisture
depletion on vegetable crop uptake of pharmaceuticals and personal care products (PPCPs).
Environ Sci Pollut Res 23:20257–20268
79. Marsik P, Sisa M, Lacina O, Motkova K, Langhansova L, Rezek J, Vanek T (2017) Metabolism
of ibuprofen in higher plants: a model Arabidopsis thaliana cell suspension culture system.
Environ Pollut 220:383–392
80. Li Y, Zhang J, Zhu G, Liu Y, Wu B, Ng WJ, Appan A, Tan SK (2016) Phytoextraction,
phytotransformation and rhizodegradation of ibuprofen associated with Typha angustifolia in a
horizontal subsurface flow constructed wetland. Water Res 102:294–304
81. Di Baccio D, Pietrini F, Bertolotto P, Pérez S, Barcelò D, Zacchini M, Donati E (2017)
Response of Lemna gibba L. to high and environmentally relevant concentrations of ibuprofen:
removal, metabolism and morpho-physiological traits for biomonitoring of emerging contaminants. Sci Total Environ 584-585:363–373
82. Pierattini EC, Francini A, Huber C, Sebastiani L, Schröder P (2018) Poplar and diclofenac
pollution: a focus on physiology, oxidative stress and uptake in plant organs. Sci Total Environ
636:944–952
83. Tai Y, Fung-Yee Tam N, Ruan W, Yang Y, Yang Y, Tao R, Zhang J (2019) Specific
metabolism related to sulfonamide tolerance and uptake in wetland plants. Chemosphere
227:496–504
84. Cui H, Schröder P (2016) Uptake, translocation and possible biodegradation of the antidiabetic
agent metformin by hydroponically grown Typha latifolia. J Hazard Mater 308:355–361
85. Cui H, de Angelis MH, Schröder P (2017) Iopromide exposure in Typha latifolia L.: evaluation
of uptake, translocation and different transformation mechanisms in planta. Water Res
122:290–298
86. Stuchlíková L, Jirásko R, Skálová L, Pavlík F, Szotáková B, Holčapek M, Vaněk T, Podlipná R
(2016) Metabolic pathways of benzimidazole anthelmintics in harebell (Campanula
rotundifolia). Chemosphere 157:10–17
522
F. Mlynek et al.
Schröder P (2017) Metabolism of ibuprofen by Phragmites australis: uptake and
phytodegradation. Environ Sci Technol 51:4576–4584
70. Kruve A, Kaupmees K, Liigand J, Leito I (2014) Negative electrospray ionization via
deprotonation: predicting the ionization efficiency. Anal Chem 86:4822–4830
71. Kruve A, Kaupmees K (2017) Predicting ESI/MS signal change for anions in different solvents.
Anal Chem 89:5079–5086
72. Wang T, Liigand J, Frandsen HL, Smedsgaard J, Kruve A (2020) Standard substances free
quantification makes LC/ESI/MS non-targeted screening of pesticides in cereals comparable
between labs. Food Chem 318:126460
73. Golan-Rozen N, Seiwert B, Riemenschneider C, Reemtsma T, Chefetz B, Hadar Y (2015)
Transformation pathways of the recalcitrant pharmaceutical compound carbamazepine by the
white-rot fungus pleurotus ostreatus: effects of growth conditions. Environ Sci Technol
49:12351–12362
74. Syranidou E, Christofilopoulos S, Gkavrou G, Thijs S, Weyens N, Vangronsveld J, Kalogerakis
N (2016) Exploitation of endophytic bacteria to enhance the phytoremediation potential of the
wetland helophyte Juncus acutus. Front Microbiol 7:1016
75. Bartha B, Huber C, Schröder P (2014) Uptake and metabolism of diclofenac in Typha latifolia –
how plants cope with human pharmaceutical pollution. Plant Sci 227:12–20
76. Kummerová M, Zezulka S, Babula P, Tříska J (2016) Possible ecological risk of two pharmaceuticals diclofenac and paracetamol demonstrated on a model plant Lemna minor. J Hazard
Mater 302:351–361
77. Pietrini F, Di Baccio D, Aceña J, Pérez S, Barceló D, Zacchini M (2015) Ibuprofen exposure in
Lemna gibba L.: evaluation of growth and phytotoxic indicators, detection of ibuprofen and
identification of its metabolites in plant and in the medium. J Hazard Mater 300:189–193
78. Santiago S, Roll DM, Ray C, Williams C, Moravcik P, Knopf A (2016) Effects of soil moisture
depletion on vegetable crop uptake of pharmaceuticals and personal care products (PPCPs).
Environ Sci Pollut Res 23:20257–20268
79. Marsik P, Sisa M, Lacina O, Motkova K, Langhansova L, Rezek J, Vanek T (2017) Metabolism
of ibuprofen in higher plants: a model Arabidopsis thaliana cell suspension culture system.
Environ Pollut 220:383–392
80. Li Y, Zhang J, Zhu G, Liu Y, Wu B, Ng WJ, Appan A, Tan SK (2016) Phytoextraction,
phytotransformation and rhizodegradation of ibuprofen associated with Typha angustifolia in a
horizontal subsurface flow constructed wetland. Water Res 102:294–304
81. Di Baccio D, Pietrini F, Bertolotto P, Pérez S, Barcelò D, Zacchini M, Donati E (2017)
Response of Lemna gibba L. to high and environmentally relevant concentrations of ibuprofen:
removal, metabolism and morpho-physiological traits for biomonitoring of emerging contaminants. Sci Total Environ 584-585:363–373
82. Pierattini EC, Francini A, Huber C, Sebastiani L, Schröder P (2018) Poplar and diclofenac
pollution: a focus on physiology, oxidative stress and uptake in plant organs. Sci Total Environ
636:944–952
83. Tai Y, Fung-Yee Tam N, Ruan W, Yang Y, Yang Y, Tao R, Zhang J (2019) Specific
metabolism related to sulfonamide tolerance and uptake in wetland plants. Chemosphere
227:496–504
84. Cui H, Schröder P (2016) Uptake, translocation and possible biodegradation of the antidiabetic
agent metformin by hydroponically grown Typha latifolia. J Hazard Mater 308:355–361
85. Cui H, de Angelis MH, Schröder P (2017) Iopromide exposure in Typha latifolia L.: evaluation
of uptake, translocation and different transformation mechanisms in planta. Water Res
122:290–298
86. Stuchlíková L, Jirásko R, Skálová L, Pavlík F, Szotáková B, Holčapek M, Vaněk T, Podlipná R
(2016) Metabolic pathways of benzimidazole anthelmintics in harebell (Campanula
rotundifolia). Chemosphere 157:10–17
522
F. Mlynek et al.