Table 6
(continued)
Matrix and target
molecules
Weight/
volume of
sample
Extraction solvent
Salts
Buffer
Clean-up
Analytical
method
Reference
Chickpea
– metformin
0,1 g dry
weight
2 mL
dichloromethane
None (sonication method)
1,9 mL (ammonium acetate
450 mmol L
À1
formic acid
50 mmol L
À1
)
SPE (Bond ElutLMS cartridges
1 mL, capacity
25 mg)
LC-ToF-MS
[42]
Celery, lettuce, cabbage,
spinach, carrot, cucumber,
bell pepper, tomato
–
16 PhACs and 3 PCP
0,2 g dry
weight
20 mL tert-butyl
ether
None (USE
method)
None
SPE clean-up (HLB
cartridge 150 mg)
UPLC-MS/
MS
[137]
Lettuce, tomato, cauliflower, and broad bean
seeds
– sulfathiazole,
sulfamethizole, sulfadiazine, sulfamethazine,
sulfadimethoxine, sulfamethoxazole, ofloxacin,
enrofloxacin, clindamycin,
and trimethoprim
1 g wet
weight
10 mL MeOH
None (USE
method)
None
SPE clean-up
(Strata-X cartridge,
100 mg/6 mL)
LC-MS/MS
(Waters TQ
detector)
[134]
Lettuce, spinach, arugula,
and radish
– carbamazepine, atenolol,
sulfamethoxazole
0,1 g dry
weight
4 mL ACN:H
2 O
(1:1, v/v, acidified
0,1% formic acid)
None (USE
method)
None
None
LC-MS/MS
QqQ
[41]
Alfalfa
– diclofenac, sulfamethoxazole, trimethoprim
5 g wet
weight
10 mL MeOH:H
2 O
(1:1, v/v)
None (USE
method)
None
SPE clean-up (Oasis
HLB)
UPLC-MS/
MS TQD
[161]
Cucumber
– 17 PPCs
0,2 g dry
weight
20 mL tert-butyl
ether
None (USE
method)
None
SPE clean-up (Oasis
HLB 150 mg)
UPLC-MS/
MS QqQ
[37]
Lettuce
– 19 PPCs
0,2 g dry
weight
20 mL tert-butyl
ether +20 mL ACN
None (USE
method)
None
SPE clean-up (Oasis
HLB
UPLC-MS/
MS
[120]
458
R. Manasfi et al.