82. Verlicchi P, Al Aukidy M, Zambello E (2012) Occurrence of pharmaceutical compounds in
urban wastewater: removal, mass load and environmental risk after a secondary treatment—a
review. Sci Total Environ 429:123–155
83. Matamoros V, García J, Bayona JM (2005) Behavior of selected pharmaceuticals in subsurface flow constructed wetlands: a pilot-scale study. Environ Sci Technol 39(14):5449–5454
84. Dordio AV, Carvalho AJP (2013) Organic xenobiotics removal in constructed wetlands, with
emphasis on the importance of the support matrix. J Hazard Mater 252–253:272–292
85. Hijosa-Valsero M et al (2016) Behaviour of pharmaceuticals and personal care products in
constructed wetland compartments: influent, effluent, pore water, substrate and plant roots.
Chemosphere 145:508–517
86. Dan A et al (2013) Removal and factors influencing removal of sulfonamides and trimethoprim from domestic sewage in constructed wetlands. Bioresour Technol 146:363–370
87. Zhang L et al (2018) New insights into the effects of support matrix on the removal of organic
micro-pollutants and the microbial community in constructed wetlands. Environ Pollut
240:699–708
88. Chaudhry Q et al (2005) Utilising the synergy between plants and rhizosphere microorganisms
to enhance breakdown of organic pollutants in the environment (15 pp). Environ Sci Pollut
Res 12(1):34–48
89. Zhang Y et al (2016) Removal of the pharmaceuticals ibuprofen and iohexol by four wetland
plant species in hydroponic culture: plant uptake and microbial degradation. Environ Sci
Pollut Res 23(3):2890–2898
90. González García M et al (2019) Predicting the uptake of emerging organic contaminants in
vegetables irrigated with treated wastewater – implications for food safety assessment. Environ Res 172:175–181
91. Zhang L et al (2017) Effects of constructed wetland design on ibuprofen removal – a
mesocosm scale study. Sci Total Environ 609:38–45
92. Petrie B et al (2018) Biotic phase micropollutant distribution in horizontal sub-surface flow
constructed wetlands. Sci Total Environ 630:648–657
93. He Y et al (2017) Metabolism of ibuprofen by Phragmites australis: uptake and
phytodegradation. Environ Sci Technol 51(8):4576–4584
94. Sauvêtre A et al (2018) Metabolism of carbamazepine in plant roots and endophytic
rhizobacteria isolated from Phragmites australis. J Hazard Mater 342:85–95
95. Villette C et al (2019) Xenobiotics metabolization in Salix alba leaves uncovered by mass
spectrometry imaging. Metabolomics 15(9):122
96. Hijosa-Valsero M et al (2011) Removal of antibiotics from urban wastewater by constructed
wetland optimization. Chemosphere 83(5):713–719
97. Hijosa-Valsero M et al (2011) Evaluation of primary treatment and loading regimes in the
removal of pharmaceuticals and personal care products from urban wastewaters by subsurfaceflow constructed wetlands. Int J Environ Anal Chem 91(7-8):632–653
98. Tai Y et al (2017) Assessment of rhizosphere processes for removing water-borne macrolide
antibiotics in constructed wetlands. Plant Soil 419(1):489–502
99. Weber KP et al (2011) Effect of ciprofloxacin on microbiological development in wetland
mesocosms. Water Res 45(10):3185–3196
100. Fernandes JP et al (2015) Microbial community dynamics associated with veterinary antibiotics removal in constructed wetlands microcosms. Bioresour Technol 182:26–33
101. Zhang Y et al (2019) Microbial community metabolic profiles in saturated constructed
wetlands treating iohexol and ibuprofen. Sci Total Environ 651:1926–1934
102. Falås P et al (2018) Transformation, CO2 formation and uptake of four organic
micropollutants by carrier-attached microorganisms. Water Res 141:405–416
103. Balcom IN et al (2016) Metagenomic analysis of an ecological wastewater treatment plant’s
microbial communities and their potential to metabolize pharmaceuticals [version 1; peer
review: 1 approved, 1 approved with reservations]. F1000Res 5:1881
412
P. N. Carvalho
urban wastewater: removal, mass load and environmental risk after a secondary treatment—a
review. Sci Total Environ 429:123–155
83. Matamoros V, García J, Bayona JM (2005) Behavior of selected pharmaceuticals in subsurface flow constructed wetlands: a pilot-scale study. Environ Sci Technol 39(14):5449–5454
84. Dordio AV, Carvalho AJP (2013) Organic xenobiotics removal in constructed wetlands, with
emphasis on the importance of the support matrix. J Hazard Mater 252–253:272–292
85. Hijosa-Valsero M et al (2016) Behaviour of pharmaceuticals and personal care products in
constructed wetland compartments: influent, effluent, pore water, substrate and plant roots.
Chemosphere 145:508–517
86. Dan A et al (2013) Removal and factors influencing removal of sulfonamides and trimethoprim from domestic sewage in constructed wetlands. Bioresour Technol 146:363–370
87. Zhang L et al (2018) New insights into the effects of support matrix on the removal of organic
micro-pollutants and the microbial community in constructed wetlands. Environ Pollut
240:699–708
88. Chaudhry Q et al (2005) Utilising the synergy between plants and rhizosphere microorganisms
to enhance breakdown of organic pollutants in the environment (15 pp). Environ Sci Pollut
Res 12(1):34–48
89. Zhang Y et al (2016) Removal of the pharmaceuticals ibuprofen and iohexol by four wetland
plant species in hydroponic culture: plant uptake and microbial degradation. Environ Sci
Pollut Res 23(3):2890–2898
90. González García M et al (2019) Predicting the uptake of emerging organic contaminants in
vegetables irrigated with treated wastewater – implications for food safety assessment. Environ Res 172:175–181
91. Zhang L et al (2017) Effects of constructed wetland design on ibuprofen removal – a
mesocosm scale study. Sci Total Environ 609:38–45
92. Petrie B et al (2018) Biotic phase micropollutant distribution in horizontal sub-surface flow
constructed wetlands. Sci Total Environ 630:648–657
93. He Y et al (2017) Metabolism of ibuprofen by Phragmites australis: uptake and
phytodegradation. Environ Sci Technol 51(8):4576–4584
94. Sauvêtre A et al (2018) Metabolism of carbamazepine in plant roots and endophytic
rhizobacteria isolated from Phragmites australis. J Hazard Mater 342:85–95
95. Villette C et al (2019) Xenobiotics metabolization in Salix alba leaves uncovered by mass
spectrometry imaging. Metabolomics 15(9):122
96. Hijosa-Valsero M et al (2011) Removal of antibiotics from urban wastewater by constructed
wetland optimization. Chemosphere 83(5):713–719
97. Hijosa-Valsero M et al (2011) Evaluation of primary treatment and loading regimes in the
removal of pharmaceuticals and personal care products from urban wastewaters by subsurfaceflow constructed wetlands. Int J Environ Anal Chem 91(7-8):632–653
98. Tai Y et al (2017) Assessment of rhizosphere processes for removing water-borne macrolide
antibiotics in constructed wetlands. Plant Soil 419(1):489–502
99. Weber KP et al (2011) Effect of ciprofloxacin on microbiological development in wetland
mesocosms. Water Res 45(10):3185–3196
100. Fernandes JP et al (2015) Microbial community dynamics associated with veterinary antibiotics removal in constructed wetlands microcosms. Bioresour Technol 182:26–33
101. Zhang Y et al (2019) Microbial community metabolic profiles in saturated constructed
wetlands treating iohexol and ibuprofen. Sci Total Environ 651:1926–1934
102. Falås P et al (2018) Transformation, CO2 formation and uptake of four organic
micropollutants by carrier-attached microorganisms. Water Res 141:405–416
103. Balcom IN et al (2016) Metagenomic analysis of an ecological wastewater treatment plant’s
microbial communities and their potential to metabolize pharmaceuticals [version 1; peer
review: 1 approved, 1 approved with reservations]. F1000Res 5:1881
412
P. N. Carvalho