Triclosan (TCS) Phase I: OH-TCS
Phase II: TCS-Gluc, TCS-Sulf
Phase II: TCS-Sulf,
TCS-Hex,
TCS-Hex-Sulf, TCS-Hex-Hex,
TCS-Hex-Mal, TCS-DeOHex-Mal-HexSulf, TCS-DeOHex-Hex-Sulf,
TSC-Hex-Mal-diSulf, TCS-DeOHexHex-Sulf, TCS-Hex-Mal-Sulf,
TCS-DeOHex-Hex, TCS-acetyl-Hex;
OH-TCS-Hex-Mal, OH-TCS-Hex-MalSulf, and more
Radish in vitro
[52]
Trimethoprim
(TMP)
Phase I: 3-NO-TMP, 1-NO-TMP,
3-Desmethyl-TMP, 4-Desmethyl-TMP,
Cα-OH-TMP,
Phase II: Cα-NAC-TMP
Phase I: (2,4-diaminopyrimidin-5- yl)(3,4,5-trimethoxyphenyl)methanone
(oxo-TMP)
Tomato and lettuce
[50]
Gluc
glucuronide conjugate, AGluc
acyl glucuronide conjugate, Sulf
sulfate conjugate, GSH
glutathione conjugate
Glucoside conjugates, Hex
hexose; DeOHex
desoxyhexose. Amino acid conjugates: Ala
alanine; Cys
cysteine; Gln
glutamine; Glu
glutamic acid; Gly
glycine;
Ile
isoleucine; Leu
leucine; Phe
phenylalanine; Ser
serine; Thr
threonine; Tyr
tyrosine; Val
valine; Mal
malonyl. Bold font indicate metabolites detected in both
human and plants
Metabolism of Pharmaceuticals in Plants and Their Associated Microbiota
237