27. Chen Z-F, Ying G-G, Ma Y-B, Lai H-J, Chen F, Pan C-G (2013) Typical azole biocides in
biosolid-amended soils and plants following biosolid applications. J Agric Food Chem
61:6198–6206
28. Li Y, Sallach B, Zhang W, Boyd SA, Li H (2019) Insight into the distribution of pharmaceuticals in soil-water-plant systems. Water Res 152:38–46
29. Kodešová R, Klement A, Golovko O, Fér M, Nikodem A, Kočárek M, Grabic R (2019) Root
uptake of atenolol, sulfamethoxazole and carbamazepine, and their transformation in three
soils and four plants. Environ Sci Pollut Res 26(10):9876–9891
30. Ben Mordechay E, Tarchitzky J, Chen Y, Shenker M, Chefetz B (2018) Composted biosolids
and treated wastewater as sources of pharmaceuticals and personal care products for plant
uptake: a case study with carbamazepine. Environ Pollut 232:164–172
31. Cortés JM, Larsson E, Jönsson JÅ (2013) Study of the uptake of non-steroid anti-inflammatory
drugs in wheat and soybean after application of sewage sludge as a fertilizer. Sci Total Environ
449:385–389
32. Fussell RJ, Garcia Lopez M, Mortimer DN, Wright S, Sehnalova M, Sinclair CJ, Fernandes A,
Sharman M (2014) Investigation into the occurrence in food of veterinary medicines, pharmaceuticals, and chemicals used in personal care products. J Agric Food Chem 62:3651–3659
33. Holling CS, Bailey JL, Heuvel BV, Kinney CA (2012) Uptake of human pharmaceuticals and
personal care products by cabbage (Brassica campestris) from fortified and biosolids-amended
soils. J Environ Monit 14:3029–3036
34. Chuang Y-H, Liu C-H, Sallach JB, Hammerschmidt R, Zhang W, Boyd SA, Li H (2019)
Mechanistic study on uptake and transport of pharmaceuticals in lettuce from water. Environ
Int 131:104976
35. Wu X, Fu Q, Gan J (2016) Metabolism of pharmaceutical and personal care products by carrot
cell cultures. Environ Pollut 211:141–147
36. Carter LJ, Williams M, Martin S, Kamaludeen SPB, Kookana RS (2018) Sorption, plant
uptake and metabolism of benzodiazepines. Sci Total Environ 628-629:18–25
37. Kong W, Liang Y, Zhang J, Smith F, Yang A (2007) Uptake of oxytetracycline and its
phytotoxicity to alfalfa (Medicago sativa L.). Environ Pollut 147:187–193
38. Kurwadkar S, Struckhoff G, Pugh K, Singh O (2017) Uptake and translocation of
sulfamethazine by alfalfa grown under hydroponic conditions. J Environ Sci 53:217–223
39. Mathews S, Henderson S, Reinhold D (2014) Uptake and accumulation of antimicrobials,
triclocarban and triclosan, by food crops in a hydroponic system. Environ Sci Pollut Res Int 21
(9):6025–6033
40. Zhang C, Xue J, Cheng D, Feng Y, Liu Y, Aly HM, Li Z (2019) Uptake, translocation and
distribution of three veterinary antibiotics in Zea mays L. Environ Pollut 250:47–57
41. Aga DS, Lenczewski M, Snow D, Muurinen J, Sallach JB, Wallace JS (2016) Challenges in
the measurement of antibiotics and in evaluating their impacts in agroecosystems: a critical
review. J Environ Qual 45(2):407–419
42. Dodgen LK, Li J, Parker D, Gan JJ (2013) Uptake and accumulation of four PPCP/EDCs in
two leafy vegetables. Environ Pollut 182:150–156
43. Wu X, Ernst F, Conkle JL, Gan J (2013) Comparative uptake and translocation of pharmaceutical and personal care products (PPCPs) by common vegetables. Environ Int 60:15–22
44. Tanoue R, Sato Y, Motoyama M, Nakagawa S, Shinohara R, Nomiyama K (2012) Plant
uptake of pharmaceutical chemicals detected in recycled organic manure and reclaimed
wastewater. J Agric Food Chem 60:10203–10211
45. Nason SL, Miller EL, Karthikeyan KG, Pedersen JA (2019) Effects of binary mixtures and
transpiration on accumulation of pharmaceuticals by spinach. Environ Sci Technol 53
(9):4850–4859
46. Dodgen LK, Ueda A, Wu X, Parker DR, Gan J (2015) Effect of transpiration on plant
accumulation and translocation of PPCP/EDCs. Environ Pollut 198:144–153
47. Emhofer L, Himmelsbach M, Buchberger W, Klampfl CW (2017) High-performance liquid
chromatography – mass spectrometry analysis of the parent drugs and their metabolites in
214
L. J. Carter et al.
biosolid-amended soils and plants following biosolid applications. J Agric Food Chem
61:6198–6206
28. Li Y, Sallach B, Zhang W, Boyd SA, Li H (2019) Insight into the distribution of pharmaceuticals in soil-water-plant systems. Water Res 152:38–46
29. Kodešová R, Klement A, Golovko O, Fér M, Nikodem A, Kočárek M, Grabic R (2019) Root
uptake of atenolol, sulfamethoxazole and carbamazepine, and their transformation in three
soils and four plants. Environ Sci Pollut Res 26(10):9876–9891
30. Ben Mordechay E, Tarchitzky J, Chen Y, Shenker M, Chefetz B (2018) Composted biosolids
and treated wastewater as sources of pharmaceuticals and personal care products for plant
uptake: a case study with carbamazepine. Environ Pollut 232:164–172
31. Cortés JM, Larsson E, Jönsson JÅ (2013) Study of the uptake of non-steroid anti-inflammatory
drugs in wheat and soybean after application of sewage sludge as a fertilizer. Sci Total Environ
449:385–389
32. Fussell RJ, Garcia Lopez M, Mortimer DN, Wright S, Sehnalova M, Sinclair CJ, Fernandes A,
Sharman M (2014) Investigation into the occurrence in food of veterinary medicines, pharmaceuticals, and chemicals used in personal care products. J Agric Food Chem 62:3651–3659
33. Holling CS, Bailey JL, Heuvel BV, Kinney CA (2012) Uptake of human pharmaceuticals and
personal care products by cabbage (Brassica campestris) from fortified and biosolids-amended
soils. J Environ Monit 14:3029–3036
34. Chuang Y-H, Liu C-H, Sallach JB, Hammerschmidt R, Zhang W, Boyd SA, Li H (2019)
Mechanistic study on uptake and transport of pharmaceuticals in lettuce from water. Environ
Int 131:104976
35. Wu X, Fu Q, Gan J (2016) Metabolism of pharmaceutical and personal care products by carrot
cell cultures. Environ Pollut 211:141–147
36. Carter LJ, Williams M, Martin S, Kamaludeen SPB, Kookana RS (2018) Sorption, plant
uptake and metabolism of benzodiazepines. Sci Total Environ 628-629:18–25
37. Kong W, Liang Y, Zhang J, Smith F, Yang A (2007) Uptake of oxytetracycline and its
phytotoxicity to alfalfa (Medicago sativa L.). Environ Pollut 147:187–193
38. Kurwadkar S, Struckhoff G, Pugh K, Singh O (2017) Uptake and translocation of
sulfamethazine by alfalfa grown under hydroponic conditions. J Environ Sci 53:217–223
39. Mathews S, Henderson S, Reinhold D (2014) Uptake and accumulation of antimicrobials,
triclocarban and triclosan, by food crops in a hydroponic system. Environ Sci Pollut Res Int 21
(9):6025–6033
40. Zhang C, Xue J, Cheng D, Feng Y, Liu Y, Aly HM, Li Z (2019) Uptake, translocation and
distribution of three veterinary antibiotics in Zea mays L. Environ Pollut 250:47–57
41. Aga DS, Lenczewski M, Snow D, Muurinen J, Sallach JB, Wallace JS (2016) Challenges in
the measurement of antibiotics and in evaluating their impacts in agroecosystems: a critical
review. J Environ Qual 45(2):407–419
42. Dodgen LK, Li J, Parker D, Gan JJ (2013) Uptake and accumulation of four PPCP/EDCs in
two leafy vegetables. Environ Pollut 182:150–156
43. Wu X, Ernst F, Conkle JL, Gan J (2013) Comparative uptake and translocation of pharmaceutical and personal care products (PPCPs) by common vegetables. Environ Int 60:15–22
44. Tanoue R, Sato Y, Motoyama M, Nakagawa S, Shinohara R, Nomiyama K (2012) Plant
uptake of pharmaceutical chemicals detected in recycled organic manure and reclaimed
wastewater. J Agric Food Chem 60:10203–10211
45. Nason SL, Miller EL, Karthikeyan KG, Pedersen JA (2019) Effects of binary mixtures and
transpiration on accumulation of pharmaceuticals by spinach. Environ Sci Technol 53
(9):4850–4859
46. Dodgen LK, Ueda A, Wu X, Parker DR, Gan J (2015) Effect of transpiration on plant
accumulation and translocation of PPCP/EDCs. Environ Pollut 198:144–153
47. Emhofer L, Himmelsbach M, Buchberger W, Klampfl CW (2017) High-performance liquid
chromatography – mass spectrometry analysis of the parent drugs and their metabolites in
214
L. J. Carter et al.