UV (330 - 365 nM)
Cu (5 mol%)
O 2 (air), solvent, base
N
H
O
N
R
R 1
N N
O
R
R 1
Scheme 58 Intramolecular imine C–H bond activation
Visible light
72 h
Ph
COOH
O
(30 mol%)
CO 2 Bn
CO 2 Bn
R 1
OH
R 2
O
O
R 1
R 2
BnO 2 C
Scheme 59 C–H alkylation/lactonization of alcohols to γ-lactones
Kessil Lamp 456 nm
UO 2 (NO3)2 6H 2 O (8 mol%)
Me 2CO, rt, air, 24 h
Z
Y
X
W
W
X
Z
Y
Scheme 60 Uranyl-photocatalysed C−H to C−C bond conversion
H
N
S
O
O
CO 2 Et
Cu(BF4)2. H 2 O (10 mol%)
Ligand (11 mol %)
PT (2 mol%)
Argon, -20°C
24 W blue LEDs
( max = 455 nm
HN
S
O
O
CO 2 Et
N
O
O
N
Me Me
Ligand
Scheme 61 C(sp3)–H activation of allylic and benzylic hydrocarbons
Blue LEDs
[RuCl2(p-cymene)] 2 (10 mol%)
KOAc (2.0 equiv)
2Me-THF
H 2 O (5.0 equiv)
RT, N 2
N
R 1
R 2
I
N
R 1
R 2
Scheme 62 Ruthenium-catalysed C–H activation reaction of arenes with aliphatic halides
CuI (0.06 mmol)
cyclohexyl isocyanide (0.06 mmol)
toluene (1.5 mL), 80 °C
O
N X
AQ
O
R 1
R 2
R 3
AQ
O
R 1
R 3
X
R 2
N
O
X = Cl or Br
Scheme 63 Copper-catalysed aminative difunctionalization of non-activated alkenes