Ali AM, Ronning HT, Alarif W, Kallenborn R, Al-Lihaibi SS (2017a) Occurrence of pharmaceuticals and personal care products in effluent-dominated Saudi Arabian coastal waters of the Red
Sea. Chemosphere 175:505–513
Ali AMM, Kallenborn R, Sydnes LK, Ronning HT, Alarif WM, Al-Lihaibi S (2017b) Photolysis of
pharmaceuticals and personal care products in the marine environment under simulated sunlight
conditions: irradiation and identification. Environ Sci Pollut Res 24(17):14657–14668
Alkadi H, Jbeily R (2018) Role of chirality in drugs: an overview. Infect Disord Drug Targets 18
(2):88–95
Amitai G, Gaidukov L, Adani R, Yishay S, Yacov G, Kushnir M, Teitlboim S, Lindenbaum M,
Bel P, Khersonsky O, Tawfik DS, Meshulam H (2006) Enhanced stereoselective hydrolysis of
toxic organophosphates by directly evolved variants of mammalian serum paraoxonase. FEBS J
273(9):1906–1919
Andres-Costa MJ, Proctor K, Sabatini MT, Gee AP, Lewis SE, Pico Y, Kasprzyk-Hordern B (2017)
Enantioselective transformation of fluoxetine in water and its ecotoxicological relevance. Sci
Rep 7(1):15777
Armstrong RN, Levin W, Ryan DE, Thomas PE, Mah HD, Jerina DM (1981) Stereoselectivity of
rat liver cytochrome P-450c on formation of benzo[a]pyrene 4,5-oxide. Biochem Biophys Res
Commun 100(3):1077–1084
Asher BJ, Ross MS, Wong CS (2012) Tracking chiral polychlorinated biphenyl sources near a
hazardous waste incinerator: fresh emissions or weathered revolatilization? Environ Toxicol
Chem 31(7):1453–1460
Asp V, Cantillana T, Bergman A, Brandt I (2010) Chiral effects in adrenocorticolytic action of o,
p
0 -DDD (mitotane) in human adrenal cells. Xenobiotica 40(3):177–183
Atkin PA, Veitch PC, Veitch EM, Ogle SJ (1999) The epidemiology of serious adverse drug
reactions among the elderly. Drugs Aging 14(2):141–152
Balasubramanian S, Gunasekaran K, Sasidharan S, Jeyamanickavel Mathan V, Perumal E (2020)
MicroRNAs and xenobiotic toxicity: an overview. Toxicol Rep 7:583–595
Ballard A, Narduolo S, Ahmad HO, Cosgrove DA, Leach AG, Buurma NJ (2019) The problem of
racemization in drug discovery and tools to predict it. Expert Opin Drug Discov 14(6):527–539
Basheer AA (2018) Chemical chiral pollution: impact on the society and science and need of the
regulations in the 21(st) century. Chirality 30(4):402–406
Basheer AA, Ali I (2018) Stereoselective uptake and degradation of (+/-)-o,p-DDD pesticide
stereomers in water-sediment system. Chirality 30(9):1088–1095
Bates HA, Rapoport H (1975) A chemical assay for saxitoxin, the paralytic shellfish poison. J Agric
Food Chem 23(2):237–239
Battiti FO, Cemaj SL, Guerrero AM, Shaik AB, Lam J, Rais R, Slusher BS, Deschamps JR, Imler
GH, Newman AH, Bonifazi A (2019) The significance of chirality in drug design and synthesis
of bitopic ligands as D3 receptor (D3R) selective agonists. J Med Chem 62(13):6287–6314
Beary 3rd JF, Eaton CR (1992) Chirality and drug development. Science 257(5067):145
Benschop HP, Konings CAG, Van Genderen J, De Jong LPA (1984) Isolation, anticholinesterase
properties, and acute toxicity in mice of the four stereoisomers of the nerve agent soman.
Toxicol Appl Pharmacol 72(1):61–74
Bidleman TF, Leone AD, Falconer RL, Harner T, Jantunen LM, Wiberg K, Helm PA, Diamond
ML, Loo B (2002) Chiral pesticides in soil and water and exchange with the atmosphere.
ScientificWorldJournal 2:357–373
Birnbaum LS, Staskal-Wikoff DS (2010) 5th international PCB workshop—summary and implications. Environ Int 36(8):814–818
Blunt JW, Copp BR, Keyzers RA, Munro MHG, Prinsep MR (2015) Marine natural products. Nat
Prod Rep 32(2):116–211
Boyd DR, Gadaginamath GS, Kher A, Malone JF, Yagi H, Jerina DM (1980) (+)- and (–)-Benzo[a]
pyrene 7,8-oxide : synthesis, absolute stereochemistry, and stereochemical correlation with
other mammalian metabolites of benzo[a]pyrene. J Chem Soc Perkin Trans 1(0):2112–2116
294
10 Chirality in Environmental Toxicity and Fate Assessments
Sea. Chemosphere 175:505–513
Ali AMM, Kallenborn R, Sydnes LK, Ronning HT, Alarif WM, Al-Lihaibi S (2017b) Photolysis of
pharmaceuticals and personal care products in the marine environment under simulated sunlight
conditions: irradiation and identification. Environ Sci Pollut Res 24(17):14657–14668
Alkadi H, Jbeily R (2018) Role of chirality in drugs: an overview. Infect Disord Drug Targets 18
(2):88–95
Amitai G, Gaidukov L, Adani R, Yishay S, Yacov G, Kushnir M, Teitlboim S, Lindenbaum M,
Bel P, Khersonsky O, Tawfik DS, Meshulam H (2006) Enhanced stereoselective hydrolysis of
toxic organophosphates by directly evolved variants of mammalian serum paraoxonase. FEBS J
273(9):1906–1919
Andres-Costa MJ, Proctor K, Sabatini MT, Gee AP, Lewis SE, Pico Y, Kasprzyk-Hordern B (2017)
Enantioselective transformation of fluoxetine in water and its ecotoxicological relevance. Sci
Rep 7(1):15777
Armstrong RN, Levin W, Ryan DE, Thomas PE, Mah HD, Jerina DM (1981) Stereoselectivity of
rat liver cytochrome P-450c on formation of benzo[a]pyrene 4,5-oxide. Biochem Biophys Res
Commun 100(3):1077–1084
Asher BJ, Ross MS, Wong CS (2012) Tracking chiral polychlorinated biphenyl sources near a
hazardous waste incinerator: fresh emissions or weathered revolatilization? Environ Toxicol
Chem 31(7):1453–1460
Asp V, Cantillana T, Bergman A, Brandt I (2010) Chiral effects in adrenocorticolytic action of o,
p
0 -DDD (mitotane) in human adrenal cells. Xenobiotica 40(3):177–183
Atkin PA, Veitch PC, Veitch EM, Ogle SJ (1999) The epidemiology of serious adverse drug
reactions among the elderly. Drugs Aging 14(2):141–152
Balasubramanian S, Gunasekaran K, Sasidharan S, Jeyamanickavel Mathan V, Perumal E (2020)
MicroRNAs and xenobiotic toxicity: an overview. Toxicol Rep 7:583–595
Ballard A, Narduolo S, Ahmad HO, Cosgrove DA, Leach AG, Buurma NJ (2019) The problem of
racemization in drug discovery and tools to predict it. Expert Opin Drug Discov 14(6):527–539
Basheer AA (2018) Chemical chiral pollution: impact on the society and science and need of the
regulations in the 21(st) century. Chirality 30(4):402–406
Basheer AA, Ali I (2018) Stereoselective uptake and degradation of (+/-)-o,p-DDD pesticide
stereomers in water-sediment system. Chirality 30(9):1088–1095
Bates HA, Rapoport H (1975) A chemical assay for saxitoxin, the paralytic shellfish poison. J Agric
Food Chem 23(2):237–239
Battiti FO, Cemaj SL, Guerrero AM, Shaik AB, Lam J, Rais R, Slusher BS, Deschamps JR, Imler
GH, Newman AH, Bonifazi A (2019) The significance of chirality in drug design and synthesis
of bitopic ligands as D3 receptor (D3R) selective agonists. J Med Chem 62(13):6287–6314
Beary 3rd JF, Eaton CR (1992) Chirality and drug development. Science 257(5067):145
Benschop HP, Konings CAG, Van Genderen J, De Jong LPA (1984) Isolation, anticholinesterase
properties, and acute toxicity in mice of the four stereoisomers of the nerve agent soman.
Toxicol Appl Pharmacol 72(1):61–74
Bidleman TF, Leone AD, Falconer RL, Harner T, Jantunen LM, Wiberg K, Helm PA, Diamond
ML, Loo B (2002) Chiral pesticides in soil and water and exchange with the atmosphere.
ScientificWorldJournal 2:357–373
Birnbaum LS, Staskal-Wikoff DS (2010) 5th international PCB workshop—summary and implications. Environ Int 36(8):814–818
Blunt JW, Copp BR, Keyzers RA, Munro MHG, Prinsep MR (2015) Marine natural products. Nat
Prod Rep 32(2):116–211
Boyd DR, Gadaginamath GS, Kher A, Malone JF, Yagi H, Jerina DM (1980) (+)- and (–)-Benzo[a]
pyrene 7,8-oxide : synthesis, absolute stereochemistry, and stereochemical correlation with
other mammalian metabolites of benzo[a]pyrene. J Chem Soc Perkin Trans 1(0):2112–2116
294
10 Chirality in Environmental Toxicity and Fate Assessments