and trans-chlordane on several cyclodextrin derivatives (e.g. heptakis(3-O-methyl2,6-di-O-n-pentyl)-β-cyclodextrin or per-O-methyl-β-cyclodextrin), the simultaneous separation of all four stereoisomers was possible only on heptakis(2-Omethyl-3,6-di-O-n-pentyl)-β-cyclodextrin.
Meanwhile, several authors applied this new experimental approach to the investigation of enzymatic transformation of cyclodiene pesticides and their metabolites
in marine and freshwater biota; see Tables 8.11 and 8.12 (Buser et al. 1992; Oehme
Cl
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H H
H H
cis-chlordane
trans-chlordane
Oxy-chlordane
Heptachlor
cis-heptachlorepoxid
trans-heptachlorepoxid
Enantiomers
Fig. 8.14 The molecular structures of cis- and trans-chlordane, oxychlordane, heptachlor, heptachlor exoepoxide, the chiral MC compounds MC 4, MC 5, MC 6, MC 7 (Miyazaki et al. 1985) and
the achiral trans- and cis-nonachlor
146
8 Enantiomer-Specific Fate and Behaviour of Chiral Contaminants