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of the particles due to agglomeration. The selection of an appropriate stabilizer is
required to prevent this phenomenon, for example, phospholipids, dimethylamine
borane (DMAB), PVA, and pluronic.
Chemical Stability
The features affecting the stability of NPs are the chemical stability of encapsulated
moieties, the molecular weight of the polymer, polymer nature, and the storage
conditions, including temperature and pH. The temperature of 4–50 °C is considPolymer solution
Polymer solution
Dialysis
Polymer solution
Non-solvent
Stirrer bar
Fig. 25.9 Diagrammatic illustration of an osmosis-based method for the preparation of PNPs
Z. Iqbal et al.