338
20. Buratti M, Campo L, Fustinoni S, Cirla P, Martinotti I, Cavallo D, et al. Urinary hydroxylated
metabolites of polycyclic aromatic hydrocarbons as biomarkers of exposure in asphalt workers. Biomarkers. 2007;12(3):221–39.
21. Harris KL, Banks LD, Mantey JA, Huderson AC, Ramesh A. Bioaccessibility of polycyclic
aromatic hydrocarbons: relevance to toxicity and carcinogenesis. Expert Opin Drug Metab
Toxicol. 2013;9(11):1465–80.
22. McClean MD, Rinehart R, Sapkota A, Cavallari J, Herrick R. Dermal exposure and urinary
1-hydroxypyrene among asphalt roofing workers. J Occup Environ Hyg. 2007;4(S1):118–26.
23. Pampanin DM, Larssen E, Øysæd KB, Sundt RC, Sydnes MO. Study of the bile proteome of
Atlantic cod (Gadus morhua): multi-biological markers of exposure to polycyclic aromatic
hydrocarbons. Mar Environ Res. 2014;101:161–8.
24. Boffetta P, Jourenkova N, Gustavsson P. Cancer risk from occupational and environmental
exposure to polycyclic aromatic hydrocarbons. Cancer Causes Control. 1997;8(3):444–72.
25. Tollefsen K, Sundt R, Beyer J, Meier S, Hylland K. Endocrine modulation in Atlantic cod
(Gadus morhua L.) exposed to alkylphenols, polyaromatic hydrocarbons, produced water, and
dispersed oil. J Toxic Environ Health A. 2011;74(7–9):529–42.
26. Wagner M, Bolm-Audorff U, Hegewald J, Fishta A, Schlattmann P, Schmitt J, et al.
Occupational polycyclic aromatic hydrocarbon exposure and risk of larynx cancer: a systematic review and meta-analysis. Occup Environ Med. 2015;72(3):226–33.
27. Koganti A, Singh R, Ma B-L, Weyand EH. Comparative analysis of PAH: DNA adducts
formed in lung of mice exposed to neat coal tar and soils contaminated with coal tar. Environ
Sci Technol. 2001;35(13):2704–9.
28. Stegeman JJ, Lech JJ. Cytochrome P-450 monooxygenase systems in aquatic species: carcinogen metabolism and biomarkers for carcinogen and pollutant exposure. Environ Health
Perspect. 1991;90:101–9.
29. Grimmer G, Brune H, Dettbarn G, Naujack K-W, Mohr U, Wenzel-Hartung R. Contribution
of polycyclic aromatic compounds to the carcinogenicity of sidestream smoke of cigarettes
evaluated by implantation into the lungs of rats. Cancer Lett. 1988;43(3):173–7.
30. Piccardo MT, Stella A, Valerio F. Is the smokers exposure to environmental tobacco smoke
negligible? Environ Health. 2010;9(1):5.
31. Hansen ÅM, Olsen ILB, Poulsen OM. Polycyclic aromatic hydrocarbons in air samples of
meat smokehouses. Sci Total Environ. 1992;126(1–2):17–26.
32. Mottier P, Parisod V, Turesky RJ. Quantitative determination of polycyclic aromatic hydrocarbons in barbecued meat sausages by gas chromatography coupled to mass spectrometry. J
Agric Food Chem. 2000;48(4):1160–6.
33. Šimko P. Determination of polycyclic aromatic hydrocarbons in smoked meat products and
smoke flavouring food additives. J Chromatogr B. 2002;770(1–2):3–18.
34. Billiard SM, Hahn ME, Franks DG, Peterson RE, Bols NC, Hodson PV. Binding of polycyclic
aromatic hydrocarbons (PAHs) to teleost aryl hydrocarbon receptors (AHRs). Comp Biochem
Physiol B Biochem Mol Biol. 2002;133(1):55–68.
35. Barron MG, Heintz R, Rice SD. Relative potency of PAHs and heterocycles as aryl hydrocarbon receptor agonists in fish. Mar Environ Res. 2004;58(2–5):95–100.
36. Shimada T, Fujii-Kuriyama Y. Metabolic activation of polycyclic aromatic hydrocarbons to
carcinogens by cytochromes P450 1A1 and1B1. Cancer Sci. 2004;95(1):1–6.
37. Kummer V, Mašková J, Zralý Z, Faldyna M. Ovarian disorders in immature rats after postnatal
exposure to environmental polycyclic aromatic hydrocarbons. J Appl Toxicol. 2013;33(2):90–9.
38. Zhang Y, Dong S, Wang H, Tao S, Kiyama R. Biological impact of environmental polycyclic
aromatic hydrocarbons (ePAHs) as endocrine disruptors. Environ Pollut. 2016;213:809–24.
39. Yin S, Tang M, Chen F, Li T, Liu W. Environmental exposure to polycyclic aromatic hydrocarbons (PAHs): the correlation with and impact on reproductive hormones in umbilical cord
serum. Environ Pollut. 2017;220:1429–37.
40. Moorthy B, Chu C, Carlin DJ. Polycyclic aromatic hydrocarbons: from metabolism to lung
cancer. Toxicol Sci. 2015;145(1):5–15.
A. Khan et al.
20. Buratti M, Campo L, Fustinoni S, Cirla P, Martinotti I, Cavallo D, et al. Urinary hydroxylated
metabolites of polycyclic aromatic hydrocarbons as biomarkers of exposure in asphalt workers. Biomarkers. 2007;12(3):221–39.
21. Harris KL, Banks LD, Mantey JA, Huderson AC, Ramesh A. Bioaccessibility of polycyclic
aromatic hydrocarbons: relevance to toxicity and carcinogenesis. Expert Opin Drug Metab
Toxicol. 2013;9(11):1465–80.
22. McClean MD, Rinehart R, Sapkota A, Cavallari J, Herrick R. Dermal exposure and urinary
1-hydroxypyrene among asphalt roofing workers. J Occup Environ Hyg. 2007;4(S1):118–26.
23. Pampanin DM, Larssen E, Øysæd KB, Sundt RC, Sydnes MO. Study of the bile proteome of
Atlantic cod (Gadus morhua): multi-biological markers of exposure to polycyclic aromatic
hydrocarbons. Mar Environ Res. 2014;101:161–8.
24. Boffetta P, Jourenkova N, Gustavsson P. Cancer risk from occupational and environmental
exposure to polycyclic aromatic hydrocarbons. Cancer Causes Control. 1997;8(3):444–72.
25. Tollefsen K, Sundt R, Beyer J, Meier S, Hylland K. Endocrine modulation in Atlantic cod
(Gadus morhua L.) exposed to alkylphenols, polyaromatic hydrocarbons, produced water, and
dispersed oil. J Toxic Environ Health A. 2011;74(7–9):529–42.
26. Wagner M, Bolm-Audorff U, Hegewald J, Fishta A, Schlattmann P, Schmitt J, et al.
Occupational polycyclic aromatic hydrocarbon exposure and risk of larynx cancer: a systematic review and meta-analysis. Occup Environ Med. 2015;72(3):226–33.
27. Koganti A, Singh R, Ma B-L, Weyand EH. Comparative analysis of PAH: DNA adducts
formed in lung of mice exposed to neat coal tar and soils contaminated with coal tar. Environ
Sci Technol. 2001;35(13):2704–9.
28. Stegeman JJ, Lech JJ. Cytochrome P-450 monooxygenase systems in aquatic species: carcinogen metabolism and biomarkers for carcinogen and pollutant exposure. Environ Health
Perspect. 1991;90:101–9.
29. Grimmer G, Brune H, Dettbarn G, Naujack K-W, Mohr U, Wenzel-Hartung R. Contribution
of polycyclic aromatic compounds to the carcinogenicity of sidestream smoke of cigarettes
evaluated by implantation into the lungs of rats. Cancer Lett. 1988;43(3):173–7.
30. Piccardo MT, Stella A, Valerio F. Is the smokers exposure to environmental tobacco smoke
negligible? Environ Health. 2010;9(1):5.
31. Hansen ÅM, Olsen ILB, Poulsen OM. Polycyclic aromatic hydrocarbons in air samples of
meat smokehouses. Sci Total Environ. 1992;126(1–2):17–26.
32. Mottier P, Parisod V, Turesky RJ. Quantitative determination of polycyclic aromatic hydrocarbons in barbecued meat sausages by gas chromatography coupled to mass spectrometry. J
Agric Food Chem. 2000;48(4):1160–6.
33. Šimko P. Determination of polycyclic aromatic hydrocarbons in smoked meat products and
smoke flavouring food additives. J Chromatogr B. 2002;770(1–2):3–18.
34. Billiard SM, Hahn ME, Franks DG, Peterson RE, Bols NC, Hodson PV. Binding of polycyclic
aromatic hydrocarbons (PAHs) to teleost aryl hydrocarbon receptors (AHRs). Comp Biochem
Physiol B Biochem Mol Biol. 2002;133(1):55–68.
35. Barron MG, Heintz R, Rice SD. Relative potency of PAHs and heterocycles as aryl hydrocarbon receptor agonists in fish. Mar Environ Res. 2004;58(2–5):95–100.
36. Shimada T, Fujii-Kuriyama Y. Metabolic activation of polycyclic aromatic hydrocarbons to
carcinogens by cytochromes P450 1A1 and1B1. Cancer Sci. 2004;95(1):1–6.
37. Kummer V, Mašková J, Zralý Z, Faldyna M. Ovarian disorders in immature rats after postnatal
exposure to environmental polycyclic aromatic hydrocarbons. J Appl Toxicol. 2013;33(2):90–9.
38. Zhang Y, Dong S, Wang H, Tao S, Kiyama R. Biological impact of environmental polycyclic
aromatic hydrocarbons (ePAHs) as endocrine disruptors. Environ Pollut. 2016;213:809–24.
39. Yin S, Tang M, Chen F, Li T, Liu W. Environmental exposure to polycyclic aromatic hydrocarbons (PAHs): the correlation with and impact on reproductive hormones in umbilical cord
serum. Environ Pollut. 2017;220:1429–37.
40. Moorthy B, Chu C, Carlin DJ. Polycyclic aromatic hydrocarbons: from metabolism to lung
cancer. Toxicol Sci. 2015;145(1):5–15.
A. Khan et al.