281
[73]. That is why EDCs accumulating in plasma cause insulin resistance and consider as risk factor to cause metabolic disorders leading to type 2 diabetes [74].
Effect on Proteins
Protein damage caused by ROS in blood, tissues, and cells can be indicated by measuring the protein carbonyls (PCs) that are biomarkers of protein oxidation [75].
The effect of MDCs on protein peroxidation has rarely studied. It has been studied
that commercial chemicals containing FIP has lethal effect on carp tissues when
applied under rice field conditions. It increases the number of protein carbonyls just
after 30–90 days with small dose (0–0.65 mg/L) under rice field conditions [73].
Fig. 17.10 Effect of pesticide on DNA
Fig. 17.11 Effect of pesticide as MDCs on obesity
17 Role of Pesticides as EDCs in Metabolic Disorders
[73]. That is why EDCs accumulating in plasma cause insulin resistance and consider as risk factor to cause metabolic disorders leading to type 2 diabetes [74].
Effect on Proteins
Protein damage caused by ROS in blood, tissues, and cells can be indicated by measuring the protein carbonyls (PCs) that are biomarkers of protein oxidation [75].
The effect of MDCs on protein peroxidation has rarely studied. It has been studied
that commercial chemicals containing FIP has lethal effect on carp tissues when
applied under rice field conditions. It increases the number of protein carbonyls just
after 30–90 days with small dose (0–0.65 mg/L) under rice field conditions [73].
Fig. 17.10 Effect of pesticide on DNA
Fig. 17.11 Effect of pesticide as MDCs on obesity
17 Role of Pesticides as EDCs in Metabolic Disorders