265
© The Editor(s) (if applicable) and The Author(s), under exclusive license
to Springer Nature Switzerland AG 2021
M. S. H. Akash et al. (eds.), Endocrine Disrupting Chemicals-induced
Metabolic Disorders and Treatment Strategies, Emerging Contaminants
and Associated Treatment Technologies,
https://doi.org/10.1007/978-3-030-45923-9_17
Chapter 17
Role of Pesticides as EDCs in Metabolic
Disorders
Shagufta Kamal, Muhammad Junaid, Ismat Bibi, Saima Rehman,
Kanwal Rehman, and Muhammad Sajid Hamid Akash
Abstract Pesticides or environmental chemicals have superiority of speed control
in conditions of massive pest outbreak against biological and cultural control practices which remained active for extended span. Nevertheless, there are severe ecological and environmental problems with reliance on pesticides. Persistence of
pesticides in the food chain and the development of resistance in pests are the two
main challenges. The unprotected populations present deleterious health effects.
Chronic effects of these environmental contaminants are neurotoxicity, carcinogenesis, developmental and reproductive disorders. In this chapter we tried to summarize the need of pesticides, history, methods of exposure. The chapter also focuses
on the metabolic disorders, interaction of recalcitrant with complex enzyme systems and influence on genders. Precautionary measures are also discussed in details.
Keywords Environmental chemicals · Deleterious health effects · Carcinogenicity
· Neurotoxicity
S. Kamal (*) · M. Junaid
Department of Biochemistry, Government College University Faisalabad,
Faisalabad, Pakistan
e-mail: shaguftakamal@gcuf.edu.pk
I. Bibi
Department of Chemistry, Islamia University, Bahawalpur, Pakistan
S. Rehman
Department of Chemistry, Government College University Faisalabad, Faisalabad, Pakistan
K. Rehman
Department of Pharmacy, University of Agriculture Faisalabad, Faisalabad, Pakistan
M. S. H. Akash
Department of Pharmaceutical Chemistry, Government College University Faisalabad,
Faisalabad, Pakistan
© The Editor(s) (if applicable) and The Author(s), under exclusive license
to Springer Nature Switzerland AG 2021
M. S. H. Akash et al. (eds.), Endocrine Disrupting Chemicals-induced
Metabolic Disorders and Treatment Strategies, Emerging Contaminants
and Associated Treatment Technologies,
https://doi.org/10.1007/978-3-030-45923-9_17
Chapter 17
Role of Pesticides as EDCs in Metabolic
Disorders
Shagufta Kamal, Muhammad Junaid, Ismat Bibi, Saima Rehman,
Kanwal Rehman, and Muhammad Sajid Hamid Akash
Abstract Pesticides or environmental chemicals have superiority of speed control
in conditions of massive pest outbreak against biological and cultural control practices which remained active for extended span. Nevertheless, there are severe ecological and environmental problems with reliance on pesticides. Persistence of
pesticides in the food chain and the development of resistance in pests are the two
main challenges. The unprotected populations present deleterious health effects.
Chronic effects of these environmental contaminants are neurotoxicity, carcinogenesis, developmental and reproductive disorders. In this chapter we tried to summarize the need of pesticides, history, methods of exposure. The chapter also focuses
on the metabolic disorders, interaction of recalcitrant with complex enzyme systems and influence on genders. Precautionary measures are also discussed in details.
Keywords Environmental chemicals · Deleterious health effects · Carcinogenicity
· Neurotoxicity
S. Kamal (*) · M. Junaid
Department of Biochemistry, Government College University Faisalabad,
Faisalabad, Pakistan
e-mail: shaguftakamal@gcuf.edu.pk
I. Bibi
Department of Chemistry, Islamia University, Bahawalpur, Pakistan
S. Rehman
Department of Chemistry, Government College University Faisalabad, Faisalabad, Pakistan
K. Rehman
Department of Pharmacy, University of Agriculture Faisalabad, Faisalabad, Pakistan
M. S. H. Akash
Department of Pharmaceutical Chemistry, Government College University Faisalabad,
Faisalabad, Pakistan