263
49. Misso ML, Murata Y, Boon WC, Jones ME, Britt KL, Simpson ER. Cellular and molecular
characterization of the adipose phenotype of the aromatase-deficient mouse. Endocrinology.
2003;144(4):1474–80. Epub 2003/03/18. eng.
50. Masuno H, Kidani T, Sekiya K, Sakayama K, Shiosaka T, Yamamoto H, et al. Bisphenol A in
combination with insulin can accelerate the conversion of 3T3-L1 fibroblasts to adipocytes. J
Lipid Res. 2002;43(5):676–84. Epub 2002/04/25. eng.
51. Sakurai K, Kawazuma M, Adachi T, Harigaya T, Saito Y, Hashimoto N, et al. Bisphenol A
affects glucose transport in mouse 3T3-F442A adipocytes. Br J Pharmacol. 2004;141(2):209–
14. Epub 2004/01/07. eng.
52. Song S, Zhang L, Zhang H, Wei W, Jia L. Perinatal BPA exposure induces hyperglycemia,
oxidative stress and decreased adiponectin production in later life of male rat offspring. Int J
Environ Res Public Health. 2014;11(4):3728–42. Epub 2014/04/08. eng.
53. Heindel JJ, vom Saal FS. Role of nutrition and environmental endocrine disrupting chemicals
during the perinatal period on the aetiology of obesity. Mol Cell Endocrinol. 2009;304(12):90–6. Epub 2009/05/13. eng.
54. Nadal A, Alonso-Magdalena P, Soriano S, Quesada I, Ropero AB. The pancreatic beta-cell
as a target of estrogens and xenoestrogens: implications for blood glucose homeostasis and
diabetes. Mol Cell Endocrinol. 2009;304(1-2):63–8. Epub 2009/05/13. eng.
55. McGarry JD. Banting lecture 2001: dysregulation of fatty acid metabolism in the etiology of
type 2 diabetes. Diabetes. 2002;51(1):7–18. Epub 2002/01/05. eng.
56. Alonso-Magdalena P, Ropero AB, Carrera MP, Cederroth CR, Baquie M, Gauthier BR,
et al. Pancreatic insulin content regulation by the estrogen receptor ER alpha. PLoS One.
2008;3(4):e2069. Epub 2008/05/01. eng.
57. Garcia-Arevalo M, Alonso-Magdalena P, Rebelo Dos Santos J, Quesada I, Carneiro EM,
Nadal A. Exposure to bisphenol-A during pregnancy partially mimics the effects of a highfat diet altering glucose homeostasis and gene expression in adult male mice. PLoS One.
2014;9(6):e100214. Epub 2014/06/25. eng.
58. Lin Y, Sun X, Qiu L, Wei J, Huang Q, Fang C, et al. Exposure to bisphenol A induces dysfunction of insulin secretion and apoptosis through the damage of mitochondria in rat insulinoma
(INS-1) cells. Cell Death Dis. 2013;4:e460. Epub 2013/01/19. eng.
59. Saltiel AR, Kahn CR. Insulin signalling and the regulation of glucose and lipid metabolism.
Nature. 2001;414(6865):799–806. Epub 2001/12/14. eng.
60. Fritsche L, Weigert C, Haring HU, Lehmann R. How insulin receptor substrate proteins regulate the metabolic capacity of the liver—implications for health and disease. Curr Med Chem.
2008;15(13):1316–29. Epub 2008/06/10. eng.
61. Alonso-Magdalena P, Vieira E, Soriano S, Menes L, Burks D, Quesada I, et al. Bisphenol A
exposure during pregnancy disrupts glucose homeostasis in mothers and adult male offspring.
Environ Health Perspect. 2010;118(9):1243–50. Epub 2010/05/22. eng.
62. Indumathi D, Jayashree S, Selvaraj J, Sathish S, Mayilvanan C, Akilavalli N, et al. Effect of
bisphenol-A on insulin signal transduction and glucose oxidation in skeletal muscle of adult
male albino rat. Hum Exp Toxicol. 2013;32(9):960–71. Epub 2013/02/21. eng.
63. Leon-Olea M, Martyniuk CJ, Orlando EF, Ottinger MA, Rosenfeld C, Wolstenholme J, et al.
Current concepts in neuroendocrine disruption. Gen Comp Endocrinol. 2014;203:158–73.
Epub 2014/02/18. eng.
64. Diano S, Horvath TL. Mitochondrial uncoupling protein 2 (UCP2) in glucose and lipid metabolism. Trends Mol Med. 2012;18(1):52–8. Epub 2011/09/16. eng.
65. Gao Q, Horvath TL. Cross-talk between estrogen and leptin signaling in the hypothalamus.
Am J Physiol Endocrinol Metab. 2008;294(5):E817–26. Epub 2008/03/13. eng.
66. Mackay H, Patterson ZR, Khazall R, Patel S, Tsirlin D, Abizaid A. Organizational effects
of perinatal exposure to bisphenol-A and diethylstilbestrol on arcuate nucleus circuitry controlling food intake and energy expenditure in male and female CD-1 mice. Endocrinology.
2013;154(4):1465–75. Epub 2013/03/16. eng.
16 Bisphenol A as an EDC in Metabolic Disorders
49. Misso ML, Murata Y, Boon WC, Jones ME, Britt KL, Simpson ER. Cellular and molecular
characterization of the adipose phenotype of the aromatase-deficient mouse. Endocrinology.
2003;144(4):1474–80. Epub 2003/03/18. eng.
50. Masuno H, Kidani T, Sekiya K, Sakayama K, Shiosaka T, Yamamoto H, et al. Bisphenol A in
combination with insulin can accelerate the conversion of 3T3-L1 fibroblasts to adipocytes. J
Lipid Res. 2002;43(5):676–84. Epub 2002/04/25. eng.
51. Sakurai K, Kawazuma M, Adachi T, Harigaya T, Saito Y, Hashimoto N, et al. Bisphenol A
affects glucose transport in mouse 3T3-F442A adipocytes. Br J Pharmacol. 2004;141(2):209–
14. Epub 2004/01/07. eng.
52. Song S, Zhang L, Zhang H, Wei W, Jia L. Perinatal BPA exposure induces hyperglycemia,
oxidative stress and decreased adiponectin production in later life of male rat offspring. Int J
Environ Res Public Health. 2014;11(4):3728–42. Epub 2014/04/08. eng.
53. Heindel JJ, vom Saal FS. Role of nutrition and environmental endocrine disrupting chemicals
during the perinatal period on the aetiology of obesity. Mol Cell Endocrinol. 2009;304(12):90–6. Epub 2009/05/13. eng.
54. Nadal A, Alonso-Magdalena P, Soriano S, Quesada I, Ropero AB. The pancreatic beta-cell
as a target of estrogens and xenoestrogens: implications for blood glucose homeostasis and
diabetes. Mol Cell Endocrinol. 2009;304(1-2):63–8. Epub 2009/05/13. eng.
55. McGarry JD. Banting lecture 2001: dysregulation of fatty acid metabolism in the etiology of
type 2 diabetes. Diabetes. 2002;51(1):7–18. Epub 2002/01/05. eng.
56. Alonso-Magdalena P, Ropero AB, Carrera MP, Cederroth CR, Baquie M, Gauthier BR,
et al. Pancreatic insulin content regulation by the estrogen receptor ER alpha. PLoS One.
2008;3(4):e2069. Epub 2008/05/01. eng.
57. Garcia-Arevalo M, Alonso-Magdalena P, Rebelo Dos Santos J, Quesada I, Carneiro EM,
Nadal A. Exposure to bisphenol-A during pregnancy partially mimics the effects of a highfat diet altering glucose homeostasis and gene expression in adult male mice. PLoS One.
2014;9(6):e100214. Epub 2014/06/25. eng.
58. Lin Y, Sun X, Qiu L, Wei J, Huang Q, Fang C, et al. Exposure to bisphenol A induces dysfunction of insulin secretion and apoptosis through the damage of mitochondria in rat insulinoma
(INS-1) cells. Cell Death Dis. 2013;4:e460. Epub 2013/01/19. eng.
59. Saltiel AR, Kahn CR. Insulin signalling and the regulation of glucose and lipid metabolism.
Nature. 2001;414(6865):799–806. Epub 2001/12/14. eng.
60. Fritsche L, Weigert C, Haring HU, Lehmann R. How insulin receptor substrate proteins regulate the metabolic capacity of the liver—implications for health and disease. Curr Med Chem.
2008;15(13):1316–29. Epub 2008/06/10. eng.
61. Alonso-Magdalena P, Vieira E, Soriano S, Menes L, Burks D, Quesada I, et al. Bisphenol A
exposure during pregnancy disrupts glucose homeostasis in mothers and adult male offspring.
Environ Health Perspect. 2010;118(9):1243–50. Epub 2010/05/22. eng.
62. Indumathi D, Jayashree S, Selvaraj J, Sathish S, Mayilvanan C, Akilavalli N, et al. Effect of
bisphenol-A on insulin signal transduction and glucose oxidation in skeletal muscle of adult
male albino rat. Hum Exp Toxicol. 2013;32(9):960–71. Epub 2013/02/21. eng.
63. Leon-Olea M, Martyniuk CJ, Orlando EF, Ottinger MA, Rosenfeld C, Wolstenholme J, et al.
Current concepts in neuroendocrine disruption. Gen Comp Endocrinol. 2014;203:158–73.
Epub 2014/02/18. eng.
64. Diano S, Horvath TL. Mitochondrial uncoupling protein 2 (UCP2) in glucose and lipid metabolism. Trends Mol Med. 2012;18(1):52–8. Epub 2011/09/16. eng.
65. Gao Q, Horvath TL. Cross-talk between estrogen and leptin signaling in the hypothalamus.
Am J Physiol Endocrinol Metab. 2008;294(5):E817–26. Epub 2008/03/13. eng.
66. Mackay H, Patterson ZR, Khazall R, Patel S, Tsirlin D, Abizaid A. Organizational effects
of perinatal exposure to bisphenol-A and diethylstilbestrol on arcuate nucleus circuitry controlling food intake and energy expenditure in male and female CD-1 mice. Endocrinology.
2013;154(4):1465–75. Epub 2013/03/16. eng.
16 Bisphenol A as an EDC in Metabolic Disorders