250
29. Johns LE, Ferguson KK, Soldin OP, Cantonwine DE, Rivera-González LO, Del Toro LVA,
et al. Urinary phthalate metabolites in relation to maternal serum thyroid and sex hormone
levels during pregnancy: a longitudinal analysis. Reprod Biol Endocrinol. 2015;13(1):4.
30. Yang X, Liu H, Liu J, Li F, Li X, Shi L, et al. Rational selection of the 3D structure of biomacromolecules for molecular docking studies on the mechanism of endocrine disruptor action.
Chem Res Toxicol. 2016;29(9):1565–70.
31. Roglic G. WHO Global report on diabetes: a summary. Int J Noncommun Dis. 2016;1(1):3.
32. Bhatia V, Viswanathan P. Insulin resistance and PPAR insulin sensitizers. Curr Opin Investig
Drugs. 2006;7(10):891–7.
33. Dales RE, Kauri LM, Cakmak S. The associations between phthalate exposure and insulin
resistance, β-cell function and blood glucose control in a population-based sample. Sci Total
Environ. 2018;612:1287–92.
34. Weldingh NM, Jørgensen-Kaur L, Becher R, Holme JA, Bodin J, Nygaard UC, et al. Bisphenol
A is more potent than phthalate metabolites in reducing pancreatic β-cell function. Biomed
Res Int. 2017;2017:1.
35. Rajesh P, Balasubramanian K. Gestational exposure to di (2-ethylhexyl) phthalate (DEHP)
impairs pancreatic β-cell function in F1 rat offspring. Toxicol Lett. 2015;232(1):46–57.
36. Lapinskas PJ, Brown S, Leesnitzer LM, Blanchard S, Swanson C, Cattley RC, et al. Role
of PPARα in mediating the effects of phthalates and metabolites in the liver. Toxicology.
2005;207(1):149–63.
37. Sarath Josh M, Pradeep S, Vijayalekshmi Amma K, Balachandran S, Abdul Jaleel U, Doble
M, et al. Phthalates efficiently bind to human peroxisome proliferator activated receptor and
retinoid X receptor α, β, γ subtypes: an in silico approach. J Appl Toxicol. 2014;34(7):754–65.
38. Sarath Josh M, Pradeep S, Adarsh V, Vijayalekshmi Amma K, Sudha Devi R, Balachandran
S, et al. In silico evidences for the binding of phthalates onto human estrogen receptor α, β
subtypes and human estrogen-related receptor γ. Mol Simul. 2014;40(5):408–17.
39. Carbone V, Velkov T. Interaction of phthalates and phenoxy acid herbicide environmental pollutants with intestinal intracellular lipid binding proteins. Chem Res Toxicol.
2013;26(8):1240–50.
40. Huang H, McIntosh AL, Martin GG, Landrock KK, Landrock D, Gupta S, et al. Structural
and functional interaction of fatty acids with human liver fatty acid-binding protein (L-FABP)
T94A variant. FEBS J. 2014;281(9):2266–83.
41. Joensen UN, Jørgensen N, Meyts ERD, Skakkebæk NE. Testicular dysgenesis syndrome and
Leydig cell function. Basic Clin Pharmacol Toxicol. 2008;102(2):155–61.
42. Lottrup G, Andersson AM, Leffers H, Mortensen G, Toppari J, Skakkebaek N, et al. Possible
impact of phthalates on infant reproductive health. Int J Androl. 2006;29(1):172–80.
43. Whyatt RM, Liu X, Rauh VA, Calafat AM, Just AC, Hoepner L, et al. Maternal prenatal
urinary phthalate metabolite concentrations and child mental, psychomotor, and behavioral
development at 3 years of age. Environ Health Perspect. 2012;120(2):290–5.
44. Bamai YA, Shibata E, Saito I, Araki A, Kanazawa A, Morimoto K, et al. Exposure to house
dust phthalates in relation to asthma and allergies in both children and adults. Sci Total
Environ. 2014;485:153–63.
45. North ML, Takaro TK, Diamond ML, Ellis AK. Effects of phthalates on the development and
expression of allergic disease and asthma. Ann Allergy Asthma Immunol. 2014;112(6):496–502.
T. Farooq et al.
29. Johns LE, Ferguson KK, Soldin OP, Cantonwine DE, Rivera-González LO, Del Toro LVA,
et al. Urinary phthalate metabolites in relation to maternal serum thyroid and sex hormone
levels during pregnancy: a longitudinal analysis. Reprod Biol Endocrinol. 2015;13(1):4.
30. Yang X, Liu H, Liu J, Li F, Li X, Shi L, et al. Rational selection of the 3D structure of biomacromolecules for molecular docking studies on the mechanism of endocrine disruptor action.
Chem Res Toxicol. 2016;29(9):1565–70.
31. Roglic G. WHO Global report on diabetes: a summary. Int J Noncommun Dis. 2016;1(1):3.
32. Bhatia V, Viswanathan P. Insulin resistance and PPAR insulin sensitizers. Curr Opin Investig
Drugs. 2006;7(10):891–7.
33. Dales RE, Kauri LM, Cakmak S. The associations between phthalate exposure and insulin
resistance, β-cell function and blood glucose control in a population-based sample. Sci Total
Environ. 2018;612:1287–92.
34. Weldingh NM, Jørgensen-Kaur L, Becher R, Holme JA, Bodin J, Nygaard UC, et al. Bisphenol
A is more potent than phthalate metabolites in reducing pancreatic β-cell function. Biomed
Res Int. 2017;2017:1.
35. Rajesh P, Balasubramanian K. Gestational exposure to di (2-ethylhexyl) phthalate (DEHP)
impairs pancreatic β-cell function in F1 rat offspring. Toxicol Lett. 2015;232(1):46–57.
36. Lapinskas PJ, Brown S, Leesnitzer LM, Blanchard S, Swanson C, Cattley RC, et al. Role
of PPARα in mediating the effects of phthalates and metabolites in the liver. Toxicology.
2005;207(1):149–63.
37. Sarath Josh M, Pradeep S, Vijayalekshmi Amma K, Balachandran S, Abdul Jaleel U, Doble
M, et al. Phthalates efficiently bind to human peroxisome proliferator activated receptor and
retinoid X receptor α, β, γ subtypes: an in silico approach. J Appl Toxicol. 2014;34(7):754–65.
38. Sarath Josh M, Pradeep S, Adarsh V, Vijayalekshmi Amma K, Sudha Devi R, Balachandran
S, et al. In silico evidences for the binding of phthalates onto human estrogen receptor α, β
subtypes and human estrogen-related receptor γ. Mol Simul. 2014;40(5):408–17.
39. Carbone V, Velkov T. Interaction of phthalates and phenoxy acid herbicide environmental pollutants with intestinal intracellular lipid binding proteins. Chem Res Toxicol.
2013;26(8):1240–50.
40. Huang H, McIntosh AL, Martin GG, Landrock KK, Landrock D, Gupta S, et al. Structural
and functional interaction of fatty acids with human liver fatty acid-binding protein (L-FABP)
T94A variant. FEBS J. 2014;281(9):2266–83.
41. Joensen UN, Jørgensen N, Meyts ERD, Skakkebæk NE. Testicular dysgenesis syndrome and
Leydig cell function. Basic Clin Pharmacol Toxicol. 2008;102(2):155–61.
42. Lottrup G, Andersson AM, Leffers H, Mortensen G, Toppari J, Skakkebaek N, et al. Possible
impact of phthalates on infant reproductive health. Int J Androl. 2006;29(1):172–80.
43. Whyatt RM, Liu X, Rauh VA, Calafat AM, Just AC, Hoepner L, et al. Maternal prenatal
urinary phthalate metabolite concentrations and child mental, psychomotor, and behavioral
development at 3 years of age. Environ Health Perspect. 2012;120(2):290–5.
44. Bamai YA, Shibata E, Saito I, Araki A, Kanazawa A, Morimoto K, et al. Exposure to house
dust phthalates in relation to asthma and allergies in both children and adults. Sci Total
Environ. 2014;485:153–63.
45. North ML, Takaro TK, Diamond ML, Ellis AK. Effects of phthalates on the development and
expression of allergic disease and asthma. Ann Allergy Asthma Immunol. 2014;112(6):496–502.
T. Farooq et al.