xv
Acknowledgement
The editors would like to express their warm thanks especially to the authors of
every chapter in this book who supported us and cooperated with us at every point
and without whom it would have been impossible to accomplish this task. It is
wholeheartedly expressed that the contribution of each author proved to be a milestone in the accomplishment of our end goal.
The support and the technical contribution of “Higher Education Commission”
(HEC) of Pakistan are highly appreciable. Without their provision and funding, it
would have been impossible to reach the objective. The credit for the accomplishment of this work goes to the research grants (21-667/SRGP/R&D/HEC/2016,
21-1061/SRGP/R&D/HEC/2016, 5661/Punjab/RPU/R&D/HEC/2016, 6429/Punjab/
NRPU/R&D/HEC/2016, and 8365/Punjab/RPU/R&D/HEC/2017) awarded by HEC
to the editors of this book, as these projects and their outcomes have provided us the
importance and significant health consequences of environmental pollutants/toxicants including heavy metals and endocrine-disrupting chemicals (EDCs). These
projects have helped us to determine the positive relation of diabetic parameters with
heavy metal exposure and influence on antioxidant status (Project# 21-667/SRGP/
R&D/HEC/2016); they have also helped us to explore the new pathways and factors
like smoking involved in the pathogenesis of metabolic disorders like diabetes and
obesity and extent of at-risk patients in our community (Project# 6429/Punjab/
NRPU/R&D/HEC/2016). Similarly, the sources for EDCs exposure and introduction
of the cost-effective treatment for EDCs-induced metabolic disturbance have been
also focused (Project#5661/Punjab/RPU/R&D/HEC/2016, 6429/Punjab/NRPU/
R&D/HEC/2016, and 8365/Punjab/RPU/R&D/HEC/2017). Nevertheless, gender
differences have also been identified to influence the inflammatory biomarkers of
insulin resistance in diabetes mellitus (Project#21-1061/SRGP/R&D/HEC/2016).
Interestingly, as in this book, many chapters have also highlighted the therapeutic impact of bioactive compounds to be a cutting-edge treatment approach for many
metabolic diseases caused by EDCs. This reflects the positive work done by the
editors of this book under HEC-funded projects for which the editors are highly
indebted to, as this funding proved to be a landmark effort towards the success of
the project.
Acknowledgement
The editors would like to express their warm thanks especially to the authors of
every chapter in this book who supported us and cooperated with us at every point
and without whom it would have been impossible to accomplish this task. It is
wholeheartedly expressed that the contribution of each author proved to be a milestone in the accomplishment of our end goal.
The support and the technical contribution of “Higher Education Commission”
(HEC) of Pakistan are highly appreciable. Without their provision and funding, it
would have been impossible to reach the objective. The credit for the accomplishment of this work goes to the research grants (21-667/SRGP/R&D/HEC/2016,
21-1061/SRGP/R&D/HEC/2016, 5661/Punjab/RPU/R&D/HEC/2016, 6429/Punjab/
NRPU/R&D/HEC/2016, and 8365/Punjab/RPU/R&D/HEC/2017) awarded by HEC
to the editors of this book, as these projects and their outcomes have provided us the
importance and significant health consequences of environmental pollutants/toxicants including heavy metals and endocrine-disrupting chemicals (EDCs). These
projects have helped us to determine the positive relation of diabetic parameters with
heavy metal exposure and influence on antioxidant status (Project# 21-667/SRGP/
R&D/HEC/2016); they have also helped us to explore the new pathways and factors
like smoking involved in the pathogenesis of metabolic disorders like diabetes and
obesity and extent of at-risk patients in our community (Project# 6429/Punjab/
NRPU/R&D/HEC/2016). Similarly, the sources for EDCs exposure and introduction
of the cost-effective treatment for EDCs-induced metabolic disturbance have been
also focused (Project#5661/Punjab/RPU/R&D/HEC/2016, 6429/Punjab/NRPU/
R&D/HEC/2016, and 8365/Punjab/RPU/R&D/HEC/2017). Nevertheless, gender
differences have also been identified to influence the inflammatory biomarkers of
insulin resistance in diabetes mellitus (Project#21-1061/SRGP/R&D/HEC/2016).
Interestingly, as in this book, many chapters have also highlighted the therapeutic impact of bioactive compounds to be a cutting-edge treatment approach for many
metabolic diseases caused by EDCs. This reflects the positive work done by the
editors of this book under HEC-funded projects for which the editors are highly
indebted to, as this funding proved to be a landmark effort towards the success of
the project.