Bourbon AI, Cerqueira MA, Vicente AA (2016) Encapsulation and controlled release of bioactive
compounds in lactoferrin-glycomacropeptide nanohydrogels: Curcumin and caffeine as model
compounds. J Food Eng 180:110–119
Bustamante A, Hinojosa A, Robert P, Escalona V (2017) Extraction and microencapsulation of
bioactive compounds from pomegranate (Punica granatum var. Wonderful) residues. Int J
Food Sci Technol 52:1452–1462
Champagne CP, Fustier P (2007) Microencapsulation for the improved delivery of bioactive
compounds into foods. Curr Opin Biotechnol 18:184–190
Chan E, Yim Z, Phan S, Mansa RF, Ravindra P (2010) Encapsulation of herbal aqueous extract
through absorption with ca-alginate hydrogel beads. Food Bioprod Process 88:195–201
Chen X, McClements DJ, Zhu Y, Zou L, Li Z, Liu W et al (2018) Gastrointestinal fate of fluid and
gelled nutraceutical emulsions: impact on proteolysis, lipolysis, and quercetin bioaccessibility.
J Agric Food Chem 66:9087–9096
Choi AY, Kim CT, Park HY, Kim HO, Lee NR, Lee KE et al (2013) Pharmacokinetic
characteristics of capsaicin-loaded nanoemulsions fabricated with alginate and chitosan.
J Agric Food Chem 61:2096–2102
Chu Z, Chen JS, Liau CT, Wang HM, Lin YC, Yang MH et al (2008) Oral bioavailability of a
novel paclitaxel formulation (Genetaxyl) administered with cyclosporin a in cancer patients.
Anticancer Drugs 19:275–281
Chuah LH, Roberts CJ, Billa N, Abdullah S, Rosli R (2014) Cellular uptake and anticancer effects
of mucoadhesive curcumin-containing chitosan nanoparticles. Colloid Surface B 116:228–236
Coimbra M, Isacchi B, van Bloois L, Torano JS, Ket A, Wu X et al (2011) Improving solubility
and chemical stability of natural compounds for medicinal use by incorporation into liposomes.
Int J Pharm 416:433–442
Cragg GM, Newman DJ (2013) Natural products: a continuing source of novel drug leads.
Biochim Biophys Acta - General Subjects 1830:3670–3695
Cui J, Yu B, Zhao Y, Zhu W, Li H, Lou H et al (2009) Enhancement of oral absorption of
curcumin by self-microemulsifying drug delivery systems. Int J Pharm 371:148–155
Da Silva BV, Barreira JCM, Oliveira MBPP (2016) Natural phytochemicals and probiotics as
bioactive ingredients for functional foods: extraction, biochemistry and protected-delivery
technologies. Trends Food Sci Technol 50:144–158
David B, Wolfender J, Dias DA (2015) The pharmaceutical industry and natural products:
historical status and new trends. Phytochem Rev 14:299–315
De Souza VB, Thomazini M, Chaves IE, Ferro-Furtado R, Favaro-Trindade CS (2020)
Microencapsulation by complex coacervation as a tool to protect bioactive compounds and
to reduce astringency and strong flavor of vegetable extracts. Food Hydrocoll 98:105244
Dias DR, Botrel DA, De Barros Fernandes VR, Borges SV (2017) Encapsulation as a tool for
bioprocessing of functional foods. Curr Opin Food Sci 13:31–37
Dima C, Patraşcu L, Cantaragiu A, Alexe P, Dima S (2016) The kinetics of the swelling process
and the release mechanisms of Coriandrum sativum L. essential oil from chitosan/alginate/
inulin microcapsules. Food Chem 195:39–48
Donsi F, Annunziata M, Sessa M, Ferrari G (2011) Nanoencapsulation of essential oils to enhance
their antimicrobial activity in foods. LWT-Food Sci Technol 44:1908–1914
Dos Santosa PP, Flores SH, Rios AO, Chiste RC (2016) Biodegradable polymers as wall materials
to the synthesis of bioactive compound nanocapsules. Trend Food Sci Technol 53:23–33
Drosou CG, Krokida MK, Biliaderis CG (2017) Encapsulation of bioactive compounds through
electrospinning/electrospraying and spray drying: a comparative assessment of food-related
applications. Drying Technol 35:139–162
Dutta RS, Hauzel L, Roy PK, Kalita P, Devi TB, Deka D et al (2018) Nanoprecipitated
ethylcellulose-curcumin particles for controlled release and enhanced antioxidant activity. Curr
Nanosci 14:298–306
Dwivedi P, Khatik R, Khandelwal K, Srivastava R, Taneja I, Rama Raju KS et al (2014)
Self-nanoemulsifying drug delivery system (SNEDDS) for oral delivery of arteether:
pharmacokinetics, toxicity and antimalarial activity in mice. RSC Adv 4:64905–64918
20 Encapsulation of Bioactive Compound and Its Therapeutic Potential
707
compounds in lactoferrin-glycomacropeptide nanohydrogels: Curcumin and caffeine as model
compounds. J Food Eng 180:110–119
Bustamante A, Hinojosa A, Robert P, Escalona V (2017) Extraction and microencapsulation of
bioactive compounds from pomegranate (Punica granatum var. Wonderful) residues. Int J
Food Sci Technol 52:1452–1462
Champagne CP, Fustier P (2007) Microencapsulation for the improved delivery of bioactive
compounds into foods. Curr Opin Biotechnol 18:184–190
Chan E, Yim Z, Phan S, Mansa RF, Ravindra P (2010) Encapsulation of herbal aqueous extract
through absorption with ca-alginate hydrogel beads. Food Bioprod Process 88:195–201
Chen X, McClements DJ, Zhu Y, Zou L, Li Z, Liu W et al (2018) Gastrointestinal fate of fluid and
gelled nutraceutical emulsions: impact on proteolysis, lipolysis, and quercetin bioaccessibility.
J Agric Food Chem 66:9087–9096
Choi AY, Kim CT, Park HY, Kim HO, Lee NR, Lee KE et al (2013) Pharmacokinetic
characteristics of capsaicin-loaded nanoemulsions fabricated with alginate and chitosan.
J Agric Food Chem 61:2096–2102
Chu Z, Chen JS, Liau CT, Wang HM, Lin YC, Yang MH et al (2008) Oral bioavailability of a
novel paclitaxel formulation (Genetaxyl) administered with cyclosporin a in cancer patients.
Anticancer Drugs 19:275–281
Chuah LH, Roberts CJ, Billa N, Abdullah S, Rosli R (2014) Cellular uptake and anticancer effects
of mucoadhesive curcumin-containing chitosan nanoparticles. Colloid Surface B 116:228–236
Coimbra M, Isacchi B, van Bloois L, Torano JS, Ket A, Wu X et al (2011) Improving solubility
and chemical stability of natural compounds for medicinal use by incorporation into liposomes.
Int J Pharm 416:433–442
Cragg GM, Newman DJ (2013) Natural products: a continuing source of novel drug leads.
Biochim Biophys Acta - General Subjects 1830:3670–3695
Cui J, Yu B, Zhao Y, Zhu W, Li H, Lou H et al (2009) Enhancement of oral absorption of
curcumin by self-microemulsifying drug delivery systems. Int J Pharm 371:148–155
Da Silva BV, Barreira JCM, Oliveira MBPP (2016) Natural phytochemicals and probiotics as
bioactive ingredients for functional foods: extraction, biochemistry and protected-delivery
technologies. Trends Food Sci Technol 50:144–158
David B, Wolfender J, Dias DA (2015) The pharmaceutical industry and natural products:
historical status and new trends. Phytochem Rev 14:299–315
De Souza VB, Thomazini M, Chaves IE, Ferro-Furtado R, Favaro-Trindade CS (2020)
Microencapsulation by complex coacervation as a tool to protect bioactive compounds and
to reduce astringency and strong flavor of vegetable extracts. Food Hydrocoll 98:105244
Dias DR, Botrel DA, De Barros Fernandes VR, Borges SV (2017) Encapsulation as a tool for
bioprocessing of functional foods. Curr Opin Food Sci 13:31–37
Dima C, Patraşcu L, Cantaragiu A, Alexe P, Dima S (2016) The kinetics of the swelling process
and the release mechanisms of Coriandrum sativum L. essential oil from chitosan/alginate/
inulin microcapsules. Food Chem 195:39–48
Donsi F, Annunziata M, Sessa M, Ferrari G (2011) Nanoencapsulation of essential oils to enhance
their antimicrobial activity in foods. LWT-Food Sci Technol 44:1908–1914
Dos Santosa PP, Flores SH, Rios AO, Chiste RC (2016) Biodegradable polymers as wall materials
to the synthesis of bioactive compound nanocapsules. Trend Food Sci Technol 53:23–33
Drosou CG, Krokida MK, Biliaderis CG (2017) Encapsulation of bioactive compounds through
electrospinning/electrospraying and spray drying: a comparative assessment of food-related
applications. Drying Technol 35:139–162
Dutta RS, Hauzel L, Roy PK, Kalita P, Devi TB, Deka D et al (2018) Nanoprecipitated
ethylcellulose-curcumin particles for controlled release and enhanced antioxidant activity. Curr
Nanosci 14:298–306
Dwivedi P, Khatik R, Khandelwal K, Srivastava R, Taneja I, Rama Raju KS et al (2014)
Self-nanoemulsifying drug delivery system (SNEDDS) for oral delivery of arteether:
pharmacokinetics, toxicity and antimalarial activity in mice. RSC Adv 4:64905–64918
20 Encapsulation of Bioactive Compound and Its Therapeutic Potential
707