Table 16.1
(continued)
Bioactivities
Gedunin/Derivatives
Experimental model
Efficacy
References
Pancrease cell line
5.0
lM
1a-hydroxy-1,2-dihydrogedunin
Leukemia cell line HL60
>20
lM
a
Kikuchi
et al. (2011)
7-deacetylgedunin
Lung cancer cell line A549
>20
lM
a
Kikuchi
et al. (2011)
Stomach cancer cell line AZ521
16.9
lM
a
Kikuchi
et al. (2011)
Breast cancer cell line SK-BR-3
12
lM
a
Kikuchi
et al. (2011)
Melanoma cell line CRL1579
>20
lM
a
Akihisa et al.
(2009),
Kikuchi
et al. (2011)
In vitro epstein-bar virus early antigen
(EBV-EA) activation assay
488 mol ratio/32 pmol TPA
a
Akihisa et al.
(2009)
Leukemia cell line HL60
2.9
lM
a
Kikuchi
et al. (2011)
7-deacetyl-7-benzoylgedunin
Lung cancer cell line A549
>20
lM
a
Kikuchi
et al. (2011)
Stomach cancer cell line AZ521
>20
lM
a
Kikuchi
et al. (2011)
Breast cancer cell line SK-BR-3
>20
lM
a
Kikuchi
et al. (2011)
Melanoma cell line CRL1579
>20
lM
a
Kikuchi
et al. (2011)
Neuroblastoma cell line SH-SY5Y
38.95
± 3.225
Lu et al.
(2009)
(continued)
568
Y. S. Ong et al.