(MIC = 31.6 µg/mL each). The remaining antifungal strains were not susceptible to
the reported alkaloids (MIC > 62.5 µg/mL). The MIC values of griseofulvin were
in the range of 3.9–7.8 µg/mL.
Wang et al. isolated various pentacyclic triterpenoids (Fig. 14.18) from the
methanolic extract of A. scholaris leaves and evaluated its antibacterial efficacy
(Wang et al. 2016) against Bacillus cereus (ATCC 9139), E. faecalis (ATCC
29212), Listeria monocytogenes (ATCC 7644), methicillin-sensitive S. aureus
(MSSA, ATCC 29213), methicillin-resistant S. aureus (MRSA, ATCC 43300),
N
H
N
H
OH
COOH
H
R
H
N
H
N
H
OH
COOH
H
MeO
O
H
N
H
N
H
OH
COO
H
MeO
H
N
H
N
H
OH
COO
H
H
H
HN
N
H
HOOC
OH
HN
N
H
OOC
OH
HN
N
H
HOOC
OH
O
N
H
O
N
OOC
N
H
N
O
OEt
HOOC
H
Alstoniascholarine A (79)
Alstoniascholarine B (80)
Alstoniascholarine C (81)
Alstoniascholarine D (82)
Alstoniascholarine E (83)
Alstoniascholarine F (84); R = H
Alstoniascholarine G (85); R = OH
Alstoniascholarine H (86); R = OMe
Alstoniascholarine I (87)
Alstoniascholarine J (88)
Alstoniascholarine K (89)
Fig. 14.17 Chemical structures of Alstoniascholarines A-K (79–89)
3-Hydroxy-11-ursen-28,13-olide (90)
O
O
HO
Fig. 14.18 Chemical structure of 3-hydroxy-11-ursen-28,13-olide (90)
480
A. T. Paul et al.