Table 13.3
(continued)
S.
No.
Cell lines
Effect and mechanism
IC
50
(µM/l)/dose
Reference
20
Human cervical cancer cell lines,
HeLa and SiHa
"Cytotoxicity, "apoptosis, "DNA fragmentation
HeLa : 50
± 5.95 mg/l
SiHa: 50
± 3.89 mg/l
Mehdi et al. (2011
21
Human HepG2 cells
Carvacrol protected cells against DNA-damaging
effects of H
2 O
2 was unambiguous
200
lM dose
Slamenova et al.
(2013)
22
Human breast cancer cell line: MCF-7
" Cytotoxicity,
"apoptosis, "caspase-3,
"caspase-9, "caspase-6, "p53, "Bax
MCF-7:244.7
± 0.71
lM
Al-Fatlawi and
Ahmad (2014)
23
Pparental and drug-resistant human
lung cancer cell lines (H1299)
" Cytotoxicity and
" membrane and DNA
damage
H1299: 380 and 244
lM
Ozkan and Erdogan
(2012)
24
Human colon carcinoma cell line
Caco-2
"Oxidative stress at higher concentration
Caco-2: 1832
± 0.11
lM
Llana-Ruiz-Cabello
et al. (2015)
25
V79 Chinese hamster lung
fibroblast
cells
DNA damage at higher concentration
Not specified
Ündeğer et al.
(2009)
450
A. Mondal et al.