3.4 Conclusion
Since long, plant polysaccharides have gained much more attention as pharmaceutical as excipients in a variety of pharmaceutical dosage forms due to some
important advantages for the uses of plant polysaccharides include easy availability
from the nature as plant resources are abundant, sustainable and low cost production, biodegradability, biocompatibility, water solubility, swelling ability, etc. Plant
polysaccharides have extensively been utilized as thickeners, suspending agents,
emulsifiers, stabilizers, gel forming agents, binders, disintegrating agents, matrix
formers, release retardants, film formers, coating materials, mucoadhesive agents,
etc., in various common pharmaceutical dosage forms, such as suspensions,
emulsions, gels, tablets, capsules, beads, microparticles, nanoparticles, liposomes,
transdermal formulations, buccal formulations, nasal formulations, ophthalmic
formulations, etc. It is anticipated that a variety of high-quality and multipurpose
pharmaceutical dosage forms will possible be formulated in the near future as a
result of the continuous research and development in the field of pharmaceutical
formulation with the successful uses of new plant polysaccharides as advanced
pharmaceutical excipient. Therefore, the future outlook in exploration and
exploitation of new plant polysaccharides as useful and multipurpose pharmaceutical excipient is extremely promising.
References
Adhikari SNR, Panda S (2017) Buccal patches of atenolol formulated using fenugreek (Trigonella
foenum-graecum L.) seed mucilage. Polim Med 47:5–11
Ahuja M, Kumar A, Yadav P, Singh K (2013) Mimosa pudica seed mucilage: Isolation,
characterization and evaluation as tablet disintegrant and binder. Int J Biol Macromol 57:
105–110
Ahuja M, Kumar S, Kumar A (2013) Evaluation of mucoadhesive potential of gum cordia, an
anionic polysaccharide. Int J Biol Macromol 55:109–112
Ali SA, Nayak AK, Sen KK, Prabhakar T (2019) Preparation and characterization of vetiver oil
encapsulated polymeric microcapsules for sedative and hypnotic activity. Int J Res Pharm Sci
10:3616–3625
Avachat A, Gujar KN, Wagh KV (2013) Development and evaluation of tamarind seed
glucan-based mucoadhesive buccal films of rizatriptan benzoate. Carbohydr Polym 91:
537–542
Avachat AM, Dash RR, Shrotriya SN (2011) Recent investigations of plant based natural gums,
mucilages and resins in novel drug delivery systems. Indian J Pharm Educ Res 45:86–99
Avlani D, Agarwal V, Khattry V, Biswas GR, Majee SB (2019) Exploring properties of sweet
basil seed mucilage in development of pharmaceutical suspensions and surfactant-free stable
emulsions. Int J Appl Pharm 11:124–129
Basu S, Chakraborty S, Bandyopadhyay AK (2007) Development and evaluation of a
mucoadhesive nasal gel of midazolam prepared with Linum usitatissimum L. seed mucilage.
Sci Pharm 77:899–910
118
A. K. Nayak et al.
Since long, plant polysaccharides have gained much more attention as pharmaceutical as excipients in a variety of pharmaceutical dosage forms due to some
important advantages for the uses of plant polysaccharides include easy availability
from the nature as plant resources are abundant, sustainable and low cost production, biodegradability, biocompatibility, water solubility, swelling ability, etc. Plant
polysaccharides have extensively been utilized as thickeners, suspending agents,
emulsifiers, stabilizers, gel forming agents, binders, disintegrating agents, matrix
formers, release retardants, film formers, coating materials, mucoadhesive agents,
etc., in various common pharmaceutical dosage forms, such as suspensions,
emulsions, gels, tablets, capsules, beads, microparticles, nanoparticles, liposomes,
transdermal formulations, buccal formulations, nasal formulations, ophthalmic
formulations, etc. It is anticipated that a variety of high-quality and multipurpose
pharmaceutical dosage forms will possible be formulated in the near future as a
result of the continuous research and development in the field of pharmaceutical
formulation with the successful uses of new plant polysaccharides as advanced
pharmaceutical excipient. Therefore, the future outlook in exploration and
exploitation of new plant polysaccharides as useful and multipurpose pharmaceutical excipient is extremely promising.
References
Adhikari SNR, Panda S (2017) Buccal patches of atenolol formulated using fenugreek (Trigonella
foenum-graecum L.) seed mucilage. Polim Med 47:5–11
Ahuja M, Kumar A, Yadav P, Singh K (2013) Mimosa pudica seed mucilage: Isolation,
characterization and evaluation as tablet disintegrant and binder. Int J Biol Macromol 57:
105–110
Ahuja M, Kumar S, Kumar A (2013) Evaluation of mucoadhesive potential of gum cordia, an
anionic polysaccharide. Int J Biol Macromol 55:109–112
Ali SA, Nayak AK, Sen KK, Prabhakar T (2019) Preparation and characterization of vetiver oil
encapsulated polymeric microcapsules for sedative and hypnotic activity. Int J Res Pharm Sci
10:3616–3625
Avachat A, Gujar KN, Wagh KV (2013) Development and evaluation of tamarind seed
glucan-based mucoadhesive buccal films of rizatriptan benzoate. Carbohydr Polym 91:
537–542
Avachat AM, Dash RR, Shrotriya SN (2011) Recent investigations of plant based natural gums,
mucilages and resins in novel drug delivery systems. Indian J Pharm Educ Res 45:86–99
Avlani D, Agarwal V, Khattry V, Biswas GR, Majee SB (2019) Exploring properties of sweet
basil seed mucilage in development of pharmaceutical suspensions and surfactant-free stable
emulsions. Int J Appl Pharm 11:124–129
Basu S, Chakraborty S, Bandyopadhyay AK (2007) Development and evaluation of a
mucoadhesive nasal gel of midazolam prepared with Linum usitatissimum L. seed mucilage.
Sci Pharm 77:899–910
118
A. K. Nayak et al.