594
A. Singhal et al.
products being used at the human scale could provide unmatched opportunities for
nanobio-constructs. In this chapter, we have examined the context of the application
of nucleic acid-based nanoconstructs in terms of orthodox environmental analysis.
Further, we provide proof-of-concept of novel nucleic acid-based nanoconstructs
toward adsorption and reuse of a clinically relevant dye. The work provides perspective to the use of nucleic acid (or other biomolecule-based) nanoconstructs for
environmental analysis in atypical contexts.
Acknowledgements The authors are grateful to the Ministry of Human Resource and Development
(MHRD), Govt. of India for financial support of this work through IMPRINT grant no. 6349.
References
Amine A, Arduini F, Moscone D, Palleschi G (2016) Recent advances in biosensors based on
enzyme inhibition. Biosens Bioelectron 76:180–194
Camacho AS, Martin-Garcia I, Contreras-Celedon C, Chacon-Garcial L, Alonso F (2017) DNAsupported palladium nanoparticles as a reusable catalyst for the copper- and ligand-free
Sonogashira reaction. Catal Sci Technol 7:2262–2273
Chilka P, Reddy PR, Datta B (2018) Dimeric carbocyanine dye and nucleic acid aptamer mediated
detection of food borne toxin. Indian J Chem 57B:281–286
Datta S, Rene CL, Sriramulu RYR (2013) Enzyme immobilization: an overview on techniques and
support materials. Biotech 3:1–9
Fu J, Liu M, Liu Y, Woodbury NW, Yan H (2012) Interenzyme substrate diffusion for an enzyme
cascade organized on spatially addressable DNA nanostructures. J Am Chem Soc 134:5516–5519
Fu J, Yang YR, Johnson-Buck A, Liu M, Liu Y, Walter NG, Woodbury NW, Yan H (2014) Multienzyme complexes on DNA scaffolds capable of substrate channeling with an artificial swinging
arm. Nat Nanotechnol 9:531–536
Gurung N, Ray S, Bose S, Rai V (2013) A broader view: microbial enzymes and their relevance in
industries, medicine and beyond. Biomed Res Int 329121
Hai H, Yang F, Li J (2013) Electrochemiluminescence sensor using quantum dots based on a
G-quadruplex aptamer for the detection of Pb 2+ . RSC Adv 3:13144–13148
Hasegawa H, Savory N, Abe K, Ikebukuro K (2016) Methods for improving aptamer binding affinity.
Molecules 21:421
Hirsch JD, Eslamizar L, Filanoski BJ, Lalekzadeh N, Haugland RP, Beecham JM, Haugland RP
(2002) Easily reversible desthiobiotin binding to streptavidin, avidin, and other biotin-binding
proteins: uses for protein labeling, detection, and isolation. Anal Biochem 308:343–357
Homaei AA, Sariri R, Vianello F, Stevanato R (2013) Enzyme immobilization: an update. J Chem
Biol 6:185–205
Hytonen VP (2017) Optimized streptavidin for fluorescent labeling of biotinylated targets. Cell
Chem Biol 24:921–922
Kirk O, Borchert TV, Fuglsang CC (2002) Industrial enzyme applications. Curr Opin Biotechnol
13:345–351
Klibanov AM, Tu TM, Scott KP (1983) Peroxidase-catalyzed removal of phenols from coalconversion waste waters. Science 221:259–261
Kumar S, Sharma P, Ratrey P, Datta B (2016) Reusable nanobiocatalysts for the efficient extraction
of pigments from orange peel. J Food Sci Technol 53:3013–3019
Li J, Lu Y (2000) A highly sensitive and selective catalytic DNA biosensor for lead ions. J Am
Chem Soc 122:10466–10467
A. Singhal et al.
products being used at the human scale could provide unmatched opportunities for
nanobio-constructs. In this chapter, we have examined the context of the application
of nucleic acid-based nanoconstructs in terms of orthodox environmental analysis.
Further, we provide proof-of-concept of novel nucleic acid-based nanoconstructs
toward adsorption and reuse of a clinically relevant dye. The work provides perspective to the use of nucleic acid (or other biomolecule-based) nanoconstructs for
environmental analysis in atypical contexts.
Acknowledgements The authors are grateful to the Ministry of Human Resource and Development
(MHRD), Govt. of India for financial support of this work through IMPRINT grant no. 6349.
References
Amine A, Arduini F, Moscone D, Palleschi G (2016) Recent advances in biosensors based on
enzyme inhibition. Biosens Bioelectron 76:180–194
Camacho AS, Martin-Garcia I, Contreras-Celedon C, Chacon-Garcial L, Alonso F (2017) DNAsupported palladium nanoparticles as a reusable catalyst for the copper- and ligand-free
Sonogashira reaction. Catal Sci Technol 7:2262–2273
Chilka P, Reddy PR, Datta B (2018) Dimeric carbocyanine dye and nucleic acid aptamer mediated
detection of food borne toxin. Indian J Chem 57B:281–286
Datta S, Rene CL, Sriramulu RYR (2013) Enzyme immobilization: an overview on techniques and
support materials. Biotech 3:1–9
Fu J, Liu M, Liu Y, Woodbury NW, Yan H (2012) Interenzyme substrate diffusion for an enzyme
cascade organized on spatially addressable DNA nanostructures. J Am Chem Soc 134:5516–5519
Fu J, Yang YR, Johnson-Buck A, Liu M, Liu Y, Walter NG, Woodbury NW, Yan H (2014) Multienzyme complexes on DNA scaffolds capable of substrate channeling with an artificial swinging
arm. Nat Nanotechnol 9:531–536
Gurung N, Ray S, Bose S, Rai V (2013) A broader view: microbial enzymes and their relevance in
industries, medicine and beyond. Biomed Res Int 329121
Hai H, Yang F, Li J (2013) Electrochemiluminescence sensor using quantum dots based on a
G-quadruplex aptamer for the detection of Pb 2+ . RSC Adv 3:13144–13148
Hasegawa H, Savory N, Abe K, Ikebukuro K (2016) Methods for improving aptamer binding affinity.
Molecules 21:421
Hirsch JD, Eslamizar L, Filanoski BJ, Lalekzadeh N, Haugland RP, Beecham JM, Haugland RP
(2002) Easily reversible desthiobiotin binding to streptavidin, avidin, and other biotin-binding
proteins: uses for protein labeling, detection, and isolation. Anal Biochem 308:343–357
Homaei AA, Sariri R, Vianello F, Stevanato R (2013) Enzyme immobilization: an update. J Chem
Biol 6:185–205
Hytonen VP (2017) Optimized streptavidin for fluorescent labeling of biotinylated targets. Cell
Chem Biol 24:921–922
Kirk O, Borchert TV, Fuglsang CC (2002) Industrial enzyme applications. Curr Opin Biotechnol
13:345–351
Klibanov AM, Tu TM, Scott KP (1983) Peroxidase-catalyzed removal of phenols from coalconversion waste waters. Science 221:259–261
Kumar S, Sharma P, Ratrey P, Datta B (2016) Reusable nanobiocatalysts for the efficient extraction
of pigments from orange peel. J Food Sci Technol 53:3013–3019
Li J, Lu Y (2000) A highly sensitive and selective catalytic DNA biosensor for lead ions. J Am
Chem Soc 122:10466–10467