16 Green Economy Approach to Develop Bioactive …
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Grafting of ILs on MNPs
Fig. 16.7 Immobilization of ILs on Fe 3 O 4 MNPs coated by silica NPs
synthesis are their less toxicity, recyclability, shorter reaction time, simplicity of
product isolation from media, reusability, relatively high product yield with good
purity, and environmental benignity which are in close proximity of green chemistry approach. Titano-magnetite was reported for easy grafting of IL on its surface
with the help of a spacer. Therefore, spacer also plays a key role in immobilization
of ILs on MNPs surface [105]. In this context, tetrabutylammonium asparaginate
(TBAAsp) with the help of organo-silane compound (spacer) was easily grafted on
Titano-magnetite (Fe 3 –xTixO 4 ) NPs surface. Thus modified Titano-magnetite NPs
with spacer was utilised as green catalyst for one-pot three-component synthesis
of 1,4-dihydropyrano[2,3-c]pyrazole derivatives. The efficiency of green modified
Titano-magnetite catalyst was subsequently decreased after six consecutive reaction
cycles; as a result, the product yield was in the range of 94–86% within 10–35 min
425
s
e
g
a
m
I
M
E
S
Grafting of ILs on MNPs
Fig. 16.7 Immobilization of ILs on Fe 3 O 4 MNPs coated by silica NPs
synthesis are their less toxicity, recyclability, shorter reaction time, simplicity of
product isolation from media, reusability, relatively high product yield with good
purity, and environmental benignity which are in close proximity of green chemistry approach. Titano-magnetite was reported for easy grafting of IL on its surface
with the help of a spacer. Therefore, spacer also plays a key role in immobilization
of ILs on MNPs surface [105]. In this context, tetrabutylammonium asparaginate
(TBAAsp) with the help of organo-silane compound (spacer) was easily grafted on
Titano-magnetite (Fe 3 –xTixO 4 ) NPs surface. Thus modified Titano-magnetite NPs
with spacer was utilised as green catalyst for one-pot three-component synthesis
of 1,4-dihydropyrano[2,3-c]pyrazole derivatives. The efficiency of green modified
Titano-magnetite catalyst was subsequently decreased after six consecutive reaction
cycles; as a result, the product yield was in the range of 94–86% within 10–35 min