12 Trends and Innovations in Biosensors for COVID-19 …
293
blood sample which contains the virus against antibodies. Thevarajan et al. (2020)
says that the basic finding report says that five days or about after the early infection
stage, the virus usually activates the immune response that stimulates the building
of both Immunoglobulin G and Immunoglobulin M in the blood which is fighting
against the virus. This body’s immune system could be found in the infected person
plasma, serum, or blood [20]. The present Point of Care biosensors and the available
devices in the market for coronavirus 2 are tabulated in Table 12.1. While, compared
to the clinical sensitivity and relatively unique, which are 79–97 which is higher than
already available POC biosensors commercially, quantitative real-time polymerase
chain reaction (qRT-PCR), COVID-19 gold standard. The 86.43–93.75 and 90.63–
100%, Immunoglobulin G/Immunoglobulin M lateral flow test strip, respectively.
12.5 Role of Biosensor in COVID-19
12.5.1 Possible Origins of Virus
Any tiny/small organism, which includes viruses/bacteria, can become airborne.
Contamination in the material can be aerosolized by various methods/ways; it
depends on air to person and animal doing things like coughing, daily activity,
sleeping, its breed, etc. [21]. If an infectious particle is clear and proper, it can
stay as an airborne, there are so many to come into proximity neither with animal
nor person and possibly form a disease. The statistical ratio of an airborne tiny
organism—microorganism causing a spread based on its spreading nature and its
capability to withstand the stress of aerosolization [22]. The latest Chinese health
statement suggested that this new coronavirus may spread quickly than what we
thought, through an “airborne route.” This microorganism is now called severe acute
respiratory syndrome coronavirus 2, disease (SARS-CoV-2), and the infection it
creates are now titled as COVID-19 [23, 24].
This virus can quickly spread over in an open/dirty environment because it tends
to grow larger and larger by joining with the airborne particles when compared with
the particles in a clean/controlled environment. After all, in clean space, the virus is
more likely to remain small and it’s hard to inhale by animals and humans. The main
spread/cause of this disease is mainly due to sneezing, coughing, talking, hugging
each other at that we sneeze, or spread the particles in a large size. The CDCP
of china almost right away changed the announcement, nothing Corona virus-2
was not considered to be an airborne virus [25, 26].
Wet/sticky droplets greater than 5–10 millionths of a meter or micrometer which is
bigger easily have the nature of falling to the land within minutes/fraction of time or
stay on a different surface. These sultry droplets are considered to be the travel risky
largest routes for the coronavirus 2 [27]. But tiny organisms haven’t been involved
in the process of CovidVirus-2. Tiny particles tend to evaporate quickly in the air
so it won’t create high-risk factors (i.e., less than 1/10 of a second is not wet air).
Précédent

- 298/437

Suivant