406
properties. Polyphenols antioxidant properties can bring about the prevention and
treatment of disease resulting from the imbalance in ROS and RNS that bring about
oxidative stress and tissue degenerative diseases. Polyphenols are also promising
nutraceutical agents; their inherent benefits should be exploited more for their bioactivity and nutraceutical applications.
References
Abusnina A, Keravis T, Yougbaré I, Bronner C, Lugnier C (2011) Anti-proliferative effect of curcumin on melanoma cells is mediated by PDE1A inhibition that regulates the epigenetic integrator UHRF1. Mol Nutr Food Res 55:1677–1689
Adlercreutz H (2007) Lignans and human health. Crit Rev Clin Lab Sci 2007(44):483–525
Aggarwal BB, Kumar A, Bharti AC (2003) Anticancer potential of curcumin: preclinical and clinical studies. Anticancer Res 23:363–398
Aguirre L, Fernández-Quintela A, Arias N, Portillo MP (2014) Resveratrol: anti-obesity mechanisms of action. Molecules 19(11):18632–18655
Ahmed SI, Hayat MQ, Tahir M, Mansoor Q, Ismail M, Keck K, Bates RB (2016) Pharmacologically
active flavonoids from the anticancer, antioxidant and antimicrobial extracts of Cassia angustifolia Vahl. BMC Complement Altern Med 16:460
Akbari M, Rasouli H, Bahdor T (2012) Physiological and pharmaceutical effect of fenugreek: a
review. IOSR J Pharm 2(4):49–53
Alhaider IA, Mohamed ME, Ahmed KKM, Kumar AHS (2017) Date palm (Phoenix dactylifera)
fruits as a potential cardioprotective agent: the role of circulating progenitor cells. Front
Pharmacol 8:592
Al-Jabban S, Zhang X, Chen G, Mekuria EA, Rakotondraibe LH, Chen Q-H (2015) Synthesis and
anti-proliferative effects of quercetin derivatives. Nat Prod Commun 10(12):2113–2118
Andarwulan N, Batari R, Sandrasari DA, Bolling B, Wijaya H (2010) Flavonoid content and antioxidant activity of vegetables from Indonesia. Food Chem 121(4):1231–1235
Andreu L, Nuncio-Jáuregui N, Carbonell-Barrachina ÁA, Legua P, Hernández F (2018) Antioxidant
properties and chemical characterization of Spanish Opuntia ficus-indica Mill. Cladodes and
fruits. J Sci Food Agric 98:1566–1573
Arts IC, Hollman PC, Feskens EJ, De Mesquita HBB, Kromhout D (2001) Catechin intake might
explain the inverse relation between tea consumption and Ischemic heart disease: the Zutphen
elderly study. Am J Clin Nutr 74(2):227–232
Barros L, Dueñas M, Pinela J, Carvalho AM, Buelga CS, Ferreira IC (2012) Characterization and
quantification of phenolic compounds in four tomato (Lycopersicon esculentum L.) farmers’
varieties in northeastern Portugal homegardens. Plant Foods Hum Nutr 67(3):229–234
Baur JA, Sinclair DA (2006) Therapeutic potential of resveratrol: the in vivo evidence. Nat Rev
Drug Discov 5(6):493–506
Beckman CH (2000) Phenolic-storing cells: keys to programmed cell death and periderm formation in wilt disease resistance and in general defence responses in plants? Physiol Mol Plant
Pathol 57:101–110
Bhat KP, Kosmeder JW, Pezzuto JM (2001) Biological effects of resveratrol. Antioxid Redox
Signal 3(6):1041–1064
Bijak M (2017) Silybin, a major bioactive component of milk thistle (Silybum marianum
L. Gaernt.) chemistry, bioavailability, and metabolism. Molecules 22:1942
Block V, Patterson B, Subar A (1992) Fruit, vegetables, and cancer prevention: a review of the
epidemiological evidence. Nutr Cancer 18:1–29
Bohm BA (1998) Introduction to flavonoids. Harwood Academic Publishers, Amsterdam
H. Tijjani et al.
properties. Polyphenols antioxidant properties can bring about the prevention and
treatment of disease resulting from the imbalance in ROS and RNS that bring about
oxidative stress and tissue degenerative diseases. Polyphenols are also promising
nutraceutical agents; their inherent benefits should be exploited more for their bioactivity and nutraceutical applications.
References
Abusnina A, Keravis T, Yougbaré I, Bronner C, Lugnier C (2011) Anti-proliferative effect of curcumin on melanoma cells is mediated by PDE1A inhibition that regulates the epigenetic integrator UHRF1. Mol Nutr Food Res 55:1677–1689
Adlercreutz H (2007) Lignans and human health. Crit Rev Clin Lab Sci 2007(44):483–525
Aggarwal BB, Kumar A, Bharti AC (2003) Anticancer potential of curcumin: preclinical and clinical studies. Anticancer Res 23:363–398
Aguirre L, Fernández-Quintela A, Arias N, Portillo MP (2014) Resveratrol: anti-obesity mechanisms of action. Molecules 19(11):18632–18655
Ahmed SI, Hayat MQ, Tahir M, Mansoor Q, Ismail M, Keck K, Bates RB (2016) Pharmacologically
active flavonoids from the anticancer, antioxidant and antimicrobial extracts of Cassia angustifolia Vahl. BMC Complement Altern Med 16:460
Akbari M, Rasouli H, Bahdor T (2012) Physiological and pharmaceutical effect of fenugreek: a
review. IOSR J Pharm 2(4):49–53
Alhaider IA, Mohamed ME, Ahmed KKM, Kumar AHS (2017) Date palm (Phoenix dactylifera)
fruits as a potential cardioprotective agent: the role of circulating progenitor cells. Front
Pharmacol 8:592
Al-Jabban S, Zhang X, Chen G, Mekuria EA, Rakotondraibe LH, Chen Q-H (2015) Synthesis and
anti-proliferative effects of quercetin derivatives. Nat Prod Commun 10(12):2113–2118
Andarwulan N, Batari R, Sandrasari DA, Bolling B, Wijaya H (2010) Flavonoid content and antioxidant activity of vegetables from Indonesia. Food Chem 121(4):1231–1235
Andreu L, Nuncio-Jáuregui N, Carbonell-Barrachina ÁA, Legua P, Hernández F (2018) Antioxidant
properties and chemical characterization of Spanish Opuntia ficus-indica Mill. Cladodes and
fruits. J Sci Food Agric 98:1566–1573
Arts IC, Hollman PC, Feskens EJ, De Mesquita HBB, Kromhout D (2001) Catechin intake might
explain the inverse relation between tea consumption and Ischemic heart disease: the Zutphen
elderly study. Am J Clin Nutr 74(2):227–232
Barros L, Dueñas M, Pinela J, Carvalho AM, Buelga CS, Ferreira IC (2012) Characterization and
quantification of phenolic compounds in four tomato (Lycopersicon esculentum L.) farmers’
varieties in northeastern Portugal homegardens. Plant Foods Hum Nutr 67(3):229–234
Baur JA, Sinclair DA (2006) Therapeutic potential of resveratrol: the in vivo evidence. Nat Rev
Drug Discov 5(6):493–506
Beckman CH (2000) Phenolic-storing cells: keys to programmed cell death and periderm formation in wilt disease resistance and in general defence responses in plants? Physiol Mol Plant
Pathol 57:101–110
Bhat KP, Kosmeder JW, Pezzuto JM (2001) Biological effects of resveratrol. Antioxid Redox
Signal 3(6):1041–1064
Bijak M (2017) Silybin, a major bioactive component of milk thistle (Silybum marianum
L. Gaernt.) chemistry, bioavailability, and metabolism. Molecules 22:1942
Block V, Patterson B, Subar A (1992) Fruit, vegetables, and cancer prevention: a review of the
epidemiological evidence. Nutr Cancer 18:1–29
Bohm BA (1998) Introduction to flavonoids. Harwood Academic Publishers, Amsterdam
H. Tijjani et al.