91
5.3 Conclusion
BAPs are organic substances of immense importance that are concealed between
structures of proteins from various natural sources. Enzymatic actions coupled with
other physical techniques can liberate these biologically active peptides during certain processes like digestion or fermentation. The BAPs have wide ranging biological activities like anti-thrombotic, antimicrobial, opioid, antihypertensive,
immuno-modulatory, antioxidative and mineral binding. Owing to these and several
other biological activities, BAPs are being used extensively in pharmaceuticals and
food industry. They are also being employed for cure and prevention of several
medical conditions. BAPs are being isolated from several natural sources such as
animals, plants, marine life, fungi etc. Natural sources are the major sources for
isolation of bioactive peptides. This chapter provides a descriptive study on the
sources from which BAPs have been isolated. Different natural sources of BAPs
like meat, collagen, dairy, hemoglobin, plants, marine and fungi along with their
potential biological importance were also discussed.
References
Abdou AM, Higashiguchi S, Aboueleinin A, Kim M, Ibrahim HR (2007) Antimicrobial peptides
derived from hen egg lysozyme with inhibitory effect against Bacillus species. Food Control
18(2):173–178
Alemán A, Gómez-Guillén MC, Montero P (2013) Identification of ace-inhibitory peptides from
squid skin collagen after in vitro gastrointestinal digestion. Food Res Int 54(1):790–795
Aneiros A, Garateix A (2004) Bioactive peptides from marine sources: pharmacological properties
and isolation procedures. J Chromatogr B 803(1):41–53
Anke H, Laatsch H (2018) Cyclic peptides and depsipeptides from fungi. In: Physiology and
genetics. Springer, Cham, pp 331–365
Arrutia F, Puente Á, Riera FA, Menéndez C, González UA (2016a) Influence of heat pre-treatment
on BSA tryptic hydrolysis and peptide release. Food Chem 202:40–48
Arrutia F, Rubio R, Riera FA (2016b) Production and membrane fractionation of bioactive peptides from a whey protein concentrate. J Food Eng 184:1–9
Bai R, Verdier-Pinard P, Gangwar S, Stessman CC, McClure KJ, Sausville EA, Pettit GR, Bates
RB, Hamel E (2001) Dolastatin 11, a marine depsipeptide, arrests cells at cytokinesis and
induces hyperpolymerization of purified actin. Mol Pharmacol 59(3):462–469
Bamdad F, Wu J, Chen L (2011) Effects of enzymatic hydrolysis on molecular structure and antioxidant activity of barley hordein. J Cereal Sci 54(1):20–28
Bertuzzi M, Hayes G, Icheoku U, van Rhijn N, Denning D, Osherov N, Bignell E (2018) AntiAspergillus activities of the respiratory epithelium in health and disease. J Fungi 4(1):8
Bhat HF, Kumar S, Bhat ZF (2015a) Bioactive peptides from egg: a review. Nutr Food Sci
45(2):190–212
Bhat ZF, Kumar S, Bhat HF (2015b) Bioactive peptides of animal origin: a review. J Food Sci
Technol 52(9):5377–5392
Bondia-Pons I, Aura A-M, Vuorela S, Kolehmainen M, Mykkänen H, Poutanen K (2009) Rye
phenolics in nutrition and health. J Cereal Sci 49(3):323–336
Boutrou R, Henry G, Sanchez-Rivera L (2015) On the trail of milk bioactive peptides in human
and animal intestinal tracts during digestion: a review. Dairy Sci Technol 95(6):815–829
5 Bioactive Peptides and Their Natural Sources
5.3 Conclusion
BAPs are organic substances of immense importance that are concealed between
structures of proteins from various natural sources. Enzymatic actions coupled with
other physical techniques can liberate these biologically active peptides during certain processes like digestion or fermentation. The BAPs have wide ranging biological activities like anti-thrombotic, antimicrobial, opioid, antihypertensive,
immuno-modulatory, antioxidative and mineral binding. Owing to these and several
other biological activities, BAPs are being used extensively in pharmaceuticals and
food industry. They are also being employed for cure and prevention of several
medical conditions. BAPs are being isolated from several natural sources such as
animals, plants, marine life, fungi etc. Natural sources are the major sources for
isolation of bioactive peptides. This chapter provides a descriptive study on the
sources from which BAPs have been isolated. Different natural sources of BAPs
like meat, collagen, dairy, hemoglobin, plants, marine and fungi along with their
potential biological importance were also discussed.
References
Abdou AM, Higashiguchi S, Aboueleinin A, Kim M, Ibrahim HR (2007) Antimicrobial peptides
derived from hen egg lysozyme with inhibitory effect against Bacillus species. Food Control
18(2):173–178
Alemán A, Gómez-Guillén MC, Montero P (2013) Identification of ace-inhibitory peptides from
squid skin collagen after in vitro gastrointestinal digestion. Food Res Int 54(1):790–795
Aneiros A, Garateix A (2004) Bioactive peptides from marine sources: pharmacological properties
and isolation procedures. J Chromatogr B 803(1):41–53
Anke H, Laatsch H (2018) Cyclic peptides and depsipeptides from fungi. In: Physiology and
genetics. Springer, Cham, pp 331–365
Arrutia F, Puente Á, Riera FA, Menéndez C, González UA (2016a) Influence of heat pre-treatment
on BSA tryptic hydrolysis and peptide release. Food Chem 202:40–48
Arrutia F, Rubio R, Riera FA (2016b) Production and membrane fractionation of bioactive peptides from a whey protein concentrate. J Food Eng 184:1–9
Bai R, Verdier-Pinard P, Gangwar S, Stessman CC, McClure KJ, Sausville EA, Pettit GR, Bates
RB, Hamel E (2001) Dolastatin 11, a marine depsipeptide, arrests cells at cytokinesis and
induces hyperpolymerization of purified actin. Mol Pharmacol 59(3):462–469
Bamdad F, Wu J, Chen L (2011) Effects of enzymatic hydrolysis on molecular structure and antioxidant activity of barley hordein. J Cereal Sci 54(1):20–28
Bertuzzi M, Hayes G, Icheoku U, van Rhijn N, Denning D, Osherov N, Bignell E (2018) AntiAspergillus activities of the respiratory epithelium in health and disease. J Fungi 4(1):8
Bhat HF, Kumar S, Bhat ZF (2015a) Bioactive peptides from egg: a review. Nutr Food Sci
45(2):190–212
Bhat ZF, Kumar S, Bhat HF (2015b) Bioactive peptides of animal origin: a review. J Food Sci
Technol 52(9):5377–5392
Bondia-Pons I, Aura A-M, Vuorela S, Kolehmainen M, Mykkänen H, Poutanen K (2009) Rye
phenolics in nutrition and health. J Cereal Sci 49(3):323–336
Boutrou R, Henry G, Sanchez-Rivera L (2015) On the trail of milk bioactive peptides in human
and animal intestinal tracts during digestion: a review. Dairy Sci Technol 95(6):815–829
5 Bioactive Peptides and Their Natural Sources