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examples and research perspectives. In: Flipo N, Labadie P, Lestel L (eds) The Seine River
basin. Handbook of environmental chemistry. Springer, Cham. https://doi.org/10.1007/698_
2019_384
Open Access This chapter is licensed under the terms of the Creative Commons Attribution 4.0
International License (http://creativecommons.org/licenses/by/4.0/), which permits use, sharing,
adaptation, distribution and reproduction in any medium or format, as long as you give appropriate
credit to the original author(s) and the source, provide a link to the Creative Commons licence and
indicate if changes were made.
The images or other third party material in this chapter are included in the chapter's Creative
Commons licence, unless indicated otherwise in a credit line to the material. If material is not
included in the chapter's Creative Commons licence and your intended use is not permitted by
statutory regulation or exceeds the permitted use, you will need to obtain permission directly from
the copyright holder.
380
P. Labadie et al.
community composition in a river influenced by a wastewater treatment plant. PLoS One 8:
e78906. https://doi.org/10.1371/journal.pone.0078906
78. Koczura R, Mokracka J, Taraszewska A, Łopacinska N (2016) Abundance of Class 1 IntegronIntegrase and sulfonamide resistance genes in river water and sediment is affected by anthropogenic pressure and environmental factors. Microb Ecol 72:909–916. https://doi.org/10.1007/
s00248-016-0843-4
79. Gillings MR, Gaze WH, Pruden A et al (2015) Using the class 1 integron-integrase gene as a
proxy for anthropogenic pollution. ISME J 9:1269–1279
80. Borruso L, Harms K, Johnsen PJ et al (2016) Distribution of class 1 integrons in a highly
impacted catchment. Sci Total Environ 566–567:1588–1594. https://doi.org/10.1016/j.
scitotenv.2016.06.054
81. Seiler C, Berendonk TU (2012) Heavy metal driven co-selection of antibiotic resistance in soil
and water bodies impacted by agriculture and aquaculture. Front Microbiol 3:399. https://doi.
org/10.3389/fmicb.2012.00399
82. Di Cesare A, Eckert E, Corno G (2016) Co-selection of antibiotic and heavy metal resistance in
freshwater bacteria. J Limnol 75. https://doi.org/10.4081/jlimnol.2016.1198
83. Fechner LC, Gourlay-Francé C, Bourgeault A, Tusseau-Vuillemin M-H (2012) Diffuse urban
pollution increases metal tolerance of natural heterotrophic biofilms. Environ Pollut 162:311–
318. https://doi.org/10.1016/j.envpol.2011.11.033
84. Bonnard M, Barijhoux L, Dedrouge-Geffard O et al (2020) Experience gained from ecotoxicological studies in the Seine River and its drainage basin over the last decade: applicative
examples and research perspectives. In: Flipo N, Labadie P, Lestel L (eds) The Seine River
basin. Handbook of environmental chemistry. Springer, Cham. https://doi.org/10.1007/698_
2019_384
Open Access This chapter is licensed under the terms of the Creative Commons Attribution 4.0
International License (http://creativecommons.org/licenses/by/4.0/), which permits use, sharing,
adaptation, distribution and reproduction in any medium or format, as long as you give appropriate
credit to the original author(s) and the source, provide a link to the Creative Commons licence and
indicate if changes were made.
The images or other third party material in this chapter are included in the chapter's Creative
Commons licence, unless indicated otherwise in a credit line to the material. If material is not
included in the chapter's Creative Commons licence and your intended use is not permitted by
statutory regulation or exceeds the permitted use, you will need to obtain permission directly from
the copyright holder.
380
P. Labadie et al.