substrate stream in a T-piece mixer that contains a titanium frit to ensure efficient gas
dispersion (Fig. 14). The hydrogen is generated internally on demand by the
electrolysis of water and the gas–liquid mixture is pumped through a suitable
catalyst contained in an interchangeable metal cartridge. An integral Peltier heater
Scheme 12 Continuous-flow reductive amination
Fig. 14 Photographic image of H-Cube
®
Scheme 11 Two synthetic schemes to access tertiary amine
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H. Miyamura and S. Kobayashi
dispersion (Fig. 14). The hydrogen is generated internally on demand by the
electrolysis of water and the gas–liquid mixture is pumped through a suitable
catalyst contained in an interchangeable metal cartridge. An integral Peltier heater
Scheme 12 Continuous-flow reductive amination
Fig. 14 Photographic image of H-Cube
®
Scheme 11 Two synthetic schemes to access tertiary amine
226
H. Miyamura and S. Kobayashi