Table 1
Substrate scope of continuous-flow hydrogenation
Entry
Substrate
Substrate
flow [μL min
À1
]
H
2 [equiv.]
T [
C]
Product
Yield
a
[g]
TON/TOF [h
À1
]
1
300
1.5
30
91.8
b
16,475/3,295
2
300
1.5
30
86.5
b
16,839/3,368
3
100
1.5
30
26.5
b
6,016/1,203
4
50
2.0
70
12.7
b
2,516/498
5
c
40
15.0
120
6.5
b
304/101
6
100
3.0
30
23.2
b
3,951/790
a
Yield of isolated product
b
Quant
c
Reaction time: 3 h
Nanoparticle Catalysts in Flow Systems
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